US6036687A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for treating venous insufficiency
Assignee: VNUS Medical Technologies LLC
•
Filing: 1996-03-05
•
Granted: 2000-03-14
•
Expires: 2016-03-05
Abstract
Abstract A catheter delivers an electrode within a vein for a minimally invasive treatment of varicose veins and venous insufficiency using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein may be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned intraluminally within the vein to treat different sections of the vein until all desired venous sections and valves are repaired and rendered functionally competent.
Inventors
- 👤 Michael D. Laufer
- 👤 Brian E. Farley
- 👤 Grace Y. Schulz
- 👤 Arthur W. Zikorus
- 👤 Mark P. Parker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:13
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/08; A61B18/12; A61B18/14; A61B18/1492; A61B17/00; A61B17/22; A61B2017/22051; A61B2017/22097; A61B2018/00053; A61B2018/00059; A61B2018/00071; A61B2018/00083; A61B2018/00214; A61B2018/0022; A61B2018/00267; A61B2018/00273; A61B2018/00279; A61B2018/00285; A61B2018/00315; A61B2018/00345; A61B2018/00404; A61B2018/00482; A61B2018/00488; A61B2018/00636; A61B2018/00696; A61B2018/00755; A61B2018/00773; A61B2018/00791; A61B2018/00797; A61B2018/00875; A61B18/1206; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1465; A61B2018/1497
Claims Analysis
Total Claims: 103
Claim 1
Independent Claim
101 words
A method of applying energy to cause shrinkage of a vein for restoring the competency of a venous valve, the method comprising the steps of: introducing a catheter having a working end and means for heating located at the working end, to a treatment site in a vein; positioning the means for heating at the treatment site in the vein; applying energy from the means for heating to heat the treatment site and cause shrinkage of the vein; terminating the emission of energy from the means for heating after sufficient shrinkage of the vein so as to restore venous valve competency.
Claim 2
Independent Claim
101 words
A method of applying energy to cause shrinkage of a vein for restoring the competency of a venous valve, the method comprising the steps of: introducing a catheter having a working end and means for heating located at the working end, to a treatment site in a vein; positioning the means for heating at the treatment site in the vein; applying energy from the means for heating to heat the treatment site and cause shrinkage of the vein; terminating the emission of energy from the means for heating after sufficient shrinkage of the vein so as to restore venous valve competency.
Claim 3
Dependent Claim
23 words
The method of claim 1, wherein the step of introducing the catheter includes the step of advancing the catheter through the saphenous vein.
Claim 4
Dependent Claim
41 words
The method of claim 1, wherein the step of positioning the means for heating at the treatment site further includes the step of placing the means for heating at the treatment site so as to minimize heating of the venous valve.
Claim 5
Dependent Claim
36 words
The method of claim 1, wherein the step of positioning the means for heating at the treatment site further includes the step of placing the means for heating across the venous valves at the treatment site.
Claim 6
Dependent Claim
39 words
The method of claim 1, wherein the step of positioning the means for heating at the treatment site further includes the step of placing the means for heating at a position below the venous valves at the treatment site.
Claim 7
Dependent Claim
46 words
The method of claim 1, wherein the step of positioning the means for heating at the treatment site further includes the steps of introducing the catheter retrograde to venous blood flow and advancing the catheter to the cusps of the venous valve at the treatment site.
Claim 8
Dependent Claim
35 words
The method of claim 1, wherein the step of positioning the means for heating further includes the step of arranging the means for heating for achieving circumferential shrinkage of the vein and minimizing axial shortening.
Claim 9
Dependent Claim
34 words
The method of claim 1, wherein the step of positioning the means for heating further includes the step of moving the means for heating into apposition with the vein wall at the treatment site.
Claim 10
Dependent Claim
83 words
The method of claim 1, wherein the step of positioning further includes the step of increasing an effective diameter of the catheter to place the means for heating into apposition with the vein wall; and the step of applying energy further includes the step of reducing the effective diameter of the catheter in a controlled manner so as to maintain apposition with the vein wall as the vein wall shrinks, until a diameter for the vein is achieved for restoring venous valve competency.
Claim 11
Dependent Claim
24 words
The method of claim 1, further comprising the step of limiting the shrinkage of the vein to an outer diameter of the heating means.
Claim 12
Dependent Claim
32 words
The method of claim 1, wherein the step of applying energy further includes the step of controlling the energy from the means for heating so as to minimize coagulation in the vein.
Claim 13
Dependent Claim
39 words
The method of claim 1, wherein the step of applying energy further includes the step of controlling the energy from the means for heating so as to control the depth of heating at the treatment site of the vein.
Claim 14
Dependent Claim
18 words
The method of claim 1, further comprising the step of determining the extent of shrinkage of the vein.
Claim 15
Dependent Claim
20 words
The method of claim 1, further comprising the step of determining the extent of shrinkage of the vein using fluoroscopy.
Claim 16
Independent Claim
108 words
A method of applying energy to cause the shrinkage of a vein for restoring the competency of a venous valve, the method comprising the steps of: introducing a catheter having a working end and at least one electrode located at the working end, to a treatment site in the vein; positioning the at least one electrode at the treatment site in the vein; applying high frequency energy from the at least one electrode to heat the treatment site and cause shrinkage of the vein; terminating the application of energy from the at least one electrode after sufficient shrinkage of the vein so as to restore venous valve competency.
Claim 17
Independent Claim
108 words
A method of applying energy to cause the shrinkage of a vein for restoring the competency of a venous valve, the method comprising the steps of: introducing a catheter having a working end and at least one electrode located at the working end, to a treatment site in the vein; positioning the at least one electrode at the treatment site in the vein; applying high frequency energy from the at least one electrode to heat the treatment site and cause shrinkage of the vein; terminating the application of energy from the at least one electrode after sufficient shrinkage of the vein so as to restore venous valve competency.
Claim 18
Dependent Claim
23 words
The method of claim 15, wherein the step of introducing the catheter includes the step of advancing the catheter through the saphenous vein.
Claim 19
Dependent Claim
37 words
The method of claim 15, wherein the step of positioning the electrode at the treatment site further includes the step of placing the electrode at the treatment site so as to minimize heating of the venous valve.
Claim 20
Dependent Claim
32 words
The method of claim 15, wherein the step of positioning the electrode at the treatment site further includes the step of placing the electrode across the venous valves at the treatment site.
Claim 21
Dependent Claim
35 words
The method of claim 15, wherein the step of positioning the electrode at the treatment site further includes the step of placing the electrode at a position below the venous valves at the treatment site.
Claim 22
Dependent Claim
43 words
The method of claim 15, wherein the step of positioning the electrode at the treatment site further includes the step of introducing the catheter retrograde to venous flow and advancing the catheter to the cusps of the venous valves at the treatment site.
Claim 23
Dependent Claim
36 words
The method of claim 15, wherein the step of positioning the electrode further includes the step of arranging a plurality of electrodes on the catheter for achieving circumferential shrinkage of the vein and minimizing axial shortening.
Claim 24
Dependent Claim
62 words
The method of claim 15, wherein the step of positioning further comprises the step of inflating a balloon with an inflation medium so that the balloon engages the vein; wherein the step of applying energy further includes the step of heating the inflation medium by the heating means, wherein the treatment site is heated by the conduction of heat from the balloon.
Claim 25
Dependent Claim
30 words
The method of claim 15, wherein the step of positioning the electrode further includes the step of moving the electrode into apposition with the vein wall at the treatment site.
Claim 26
Dependent Claim
38 words
The method of claim 15, wherein the step of positioning further includes the step of deflecting an elongate member radially outward from the catheter to place the electrode in apposition with the vein wall at the treatment site.
Claim 27
Dependent Claim
46 words
The method of claim 15, wherein the step of positioning further includes the step of inflating a balloon on the catheter to engage an elongate member, wherein the elongate member is deflected to place the electrode in apposition with the vein wall at the treatment site.
Claim 28
Dependent Claim
37 words
The method of claim 15, wherein the step of positioning the electrode at the treatment site further includes the step of inflating a balloon on the catheter to move the electrode into apposition with the vein wall.
Claim 29
Dependent Claim
53 words
The method of claim 15, wherein the step of positioning further includes the step of driving a shaft having a wedge tip through the catheter to radially deflect the electrodes on the working end of the catheter outwardly so as to place the electrode in apposition with the vein at the treatment site.
Claim 30
Dependent Claim
38 words
The method of claim 15, wherein the step of positioning further includes the step of providing an external tourniquet to compress the vein so that the electrode is placed in apposition with the vein at the treatment site.
Claim 31
Dependent Claim
40 words
The method of claim 15, wherein the step of positioning further includes the step of moving a bent deflection wire through the catheter to deflect the catheter and the electrode to one side of the vein at the treatment site.
Claim 32
Dependent Claim
51 words
The method of claim 15, wherein the step of positioning further includes the step of actuating a bowable deflection wire on one side of the catheter so as to move the catheter, and the electrode on the side of the catheter opposite the deflection wire to one side of the vein.
Claim 33
Dependent Claim
52 words
The method of claim 15, wherein the step of positioning further includes the step of inflating a balloon on one side of the catheter so as to move the catheter, and the electrode on the side of the catheter opposite the balloon, to one side of the vein at the treatment site.
Claim 34
Dependent Claim
31 words
The method of claim 15, wherein the step of positioning further includes the step of inflating a balloon on the catheter to center the catheter and the electrode within the vein.
Claim 35
Dependent Claim
56 words
The method of claim 15, wherein the step of positioning further includes the step of inflating a balloon on the catheter to occlude the vein so as to limit blood flow within the vein between the balloon and the venous valve of the vein, wherein the working end is between the balloon and the venous valve.
Claim 36
Dependent Claim
26 words
The method of claim 15, wherein the step of applying energy further includes the step of limiting the shrinkage of the vein to a selected diameter.
Claim 37
Dependent Claim
43 words
The method of claim 15, wherein the step of applying energy further includes the step of limiting the shrinkage of the vein by inflating a balloon to a selected diameter; wherein the inflated balloon prevents shrinkage of the vein beyond the selected diameter.
Claim 38
Dependent Claim
76 words
The method of claim 15, wherein the step of positioning the electrode further includes the step of placing the electrode into apposition with the vein wall; and the step of applying energy further includes the step of reducing an effective diameter of the catheter in a controlled manner so as to maintain apposition with the vein wall as the vein wall shrinks, until a selected diameter for the vein is achieved for restoring venous valve competency.
Claim 39
Dependent Claim
84 words
The method of claim 34, wherein the step of positioning the electrode further includes the step of placing the electrode into apposition with the vein by increasing an effective diameter of the catheter, wherein the shrinkage of the vein reduces the effective diameter of the catheter; and the step of limiting the shrinkage of the vein further includes the step of preventing the effective diameter of the catheter from being reduced to less than a selected diameter representing the sufficient shrinkage of the vein.
Claim 40
Dependent Claim
33 words
The method of claim 15, wherein the step of applying energy further includes the step of limiting the shrinkage of the vein to the fixed diameter of the catheter at the working end.
Claim 41
Dependent Claim
35 words
The method of claim 15, wherein the step of applying high frequency energy further includes the step of controlling the frequency of the energy from the electrode so as to minimize coagulation in the vein.
Claim 42
Dependent Claim
42 words
The method of claim 15, wherein the step of applying high frequency energy further includes the step of controlling the frequency of the energy from the electrode so as to control the spread of heating at the treatment site of the vein.
Claim 43
Dependent Claim
61 words
The method of claim 15, wherein the electrode includes a plurality of longitudinal electrode, and the step of applying the high frequency energy further includes the step of providing the high frequency energy to the longitudinal electrode along the circumference of the working end of the catheter; wherein the vein is shrunk circumferentially and axial shrinkage of the vein is minimized.
Claim 44
Dependent Claim
44 words
The method of claim 15, wherein the step of applying the high frequency energy further includes the step of providing an inert cap at the working end of the catheter past the electrode to prevent vein shrinkage past the working end of the catheter.
Claim 45
Dependent Claim
37 words
The method of claim 15, wherein the step of applying energy further includes the step of providing the catheter with a bend towards the working end; and rotating the catheter so as to create a stirring effect.
Claim 46
Dependent Claim
22 words
The method of claim 15, further comprising the step of delivering a cooling fluid to the treatment site for preventing thermal coagulation.
Claim 47
Dependent Claim
18 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein.
Claim 48
Dependent Claim
20 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein using fluoroscopy.
Claim 49
Dependent Claim
21 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein using ultrasound imaging.
Claim 50
Dependent Claim
21 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein using pulse-echo ultrasound.
Claim 51
Dependent Claim
21 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein using external ultrasound.
Claim 52
Dependent Claim
26 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein by measuring the impedance of the treatment site.
Claim 53
Dependent Claim
26 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein by measuring the temperature of the treatment site.
Claim 54
Dependent Claim
21 words
The method of claim 15, further comprising the step of determining the extent of shrinkage of the vein using an angioscope.
Claim 55
Dependent Claim
62 words
The method of claim 15, wherein the step of positioning further comprises the step of inflating a balloon with an inflation medium so that the balloon engages the vein; wherein the step of applying energy further includes the step of heating the inflation medium by the heating means, wherein the treatment site is heated by the conduction of heat from the balloon.
Claim 56
Independent Claim
93 words
A method of applying energy to cause shrinkage of a dilated vein, the method comprising the steps of: introducing a catheter having a working end and means for heating located at the working end, to a treatment site in a vein; positioning the means for heating at the treatment site in the vein; applying energy from the means for heating to heat the treatment site and cause shrinkage of the vein; terminating the emission of energy from the means for heating after sufficient shrinkage of the vein so that the vein remains patent.
Claim 57
Independent Claim
93 words
A method of applying energy to cause shrinkage of a dilated vein, the method comprising the steps of: introducing a catheter having a working end and means for heating located at the working end, to a treatment site in a vein; positioning the means for heating at the treatment site in the vein; applying energy from the means for heating to heat the treatment site and cause shrinkage of the vein; terminating the emission of energy from the means for heating after sufficient shrinkage of the vein so that the vein remains patent.
Claim 58
Dependent Claim
23 words
The method of claim 54, wherein the step of introducing the catheter includes the step of advancing the catheter through the saphenous vein.
Claim 59
Dependent Claim
41 words
The method of claim 54, wherein the step of positioning the means for heating at the treatment site further includes the step of placing the means for heating at the treatment site so as to minimize heating of the venous valve.
Claim 60
Dependent Claim
35 words
The method of claim 54, wherein the step of positioning the means for heating further includes the step of arranging the means for heating for achieving circumferential shrinkage of the vein and minimizing axial shortening.
Claim 61
Dependent Claim
34 words
The method of claim 54, wherein the step of positioning the means for heating further includes the step of moving the means for heating into apposition with the vein wall at the treatment site.
Claim 62
Dependent Claim
79 words
The method of claim 54, wherein the step of positioning further includes the step of increasing an effective diameter of the catheter to place the means for heating into apposition with the vein wall; and the step of applying energy further includes the step of reducing the effective diameter of the catheter so as to maintain apposition with the vein wall as the vein wall shrinks, until a diameter for the vein is achieved for restoring venous valve competency.
Claim 63
Dependent Claim
26 words
The method of claim 54, wherein the step of applying energy further includes the step of limiting the shrinkage of the vein to a selected diameter.
Claim 64
Dependent Claim
32 words
The method of claim 54, wherein the step of applying energy further includes the step of controlling the energy from the means for heating so as to minimize coagulation in the vein.
Claim 65
Dependent Claim
39 words
The method of claim 54, wherein the step of applying energy further includes the step of controlling the energy from the means for heating so as to control the spread of heating at the treatment site of the vein.
Claim 66
Dependent Claim
18 words
The method of claim 54, further comprising the step of determining the extent of shrinkage of the vein.
Claim 67
Dependent Claim
20 words
The method of claim 54, further comprising the step of determining the extent of shrinkage of the vein using fluoroscopy.
Claim 68
Independent Claim
93 words
A method of applying energy to cause the shrinkage of a dilated vein, the method comprising the steps of: introducing a catheter having a working end and at least one electrode located at the working end, to a treatment site in the vein; positioning the electrode at the treatment site in the vein; applying radiant high frequency energy from the electrode to heat the treatment site and cause shrinkage of the vein; terminating the applying of radiant energy from the electrode after sufficient shrinkage of the vein so that the vein remains patent.
Claim 69
Independent Claim
93 words
A method of applying energy to cause the shrinkage of a dilated vein, the method comprising the steps of: introducing a catheter having a working end and at least one electrode located at the working end, to a treatment site in the vein; positioning the electrode at the treatment site in the vein; applying radiant high frequency energy from the electrode to heat the treatment site and cause shrinkage of the vein; terminating the applying of radiant energy from the electrode after sufficient shrinkage of the vein so that the vein remains patent.
Claim 70
Dependent Claim
23 words
The method of claim 65, wherein the step of introducing the catheter includes the step of advancing the catheter through the saphenous vein.
Claim 71
Dependent Claim
37 words
The method of claim 65, wherein the step of positioning the electrode at the treatment site further includes the step of placing the electrode at the treatment site so as to minimize heating of the venous valve.
Claim 72
Dependent Claim
36 words
The method of claim 65, wherein the step of positioning the electrode further includes the step of arranging a plurality of electrodes on the catheter for achieving circumferential shrinkage of the vein and minimizing axial shortening.
Claim 73
Dependent Claim
30 words
The method of claim 64, wherein the step of positioning the electrode further includes the step of moving the electrode into apposition with the vein wall at the treatment site.
Claim 74
Dependent Claim
33 words
The method of claim 64, wherein the step of positioning further includes the step of deflecting an elongate member to place the electrode in apposition with the vein wall at the treatment site.
Claim 75
Dependent Claim
46 words
The method of claim 64, wherein the step of positioning further includes the step of inflating a balloon on the catheter to engage an elongate member, wherein the elongate member is deflected to place the electrode in apposition with the vein wall at the treatment site.
Claim 76
Dependent Claim
37 words
The method of claim 64, wherein the step of positioning the electrode at the treatment site further includes the step of inflating a balloon on the catheter to move the electrode into apposition with the vein wall.
Claim 77
Dependent Claim
53 words
The method of claim 64, wherein the step of positioning further includes the step of driving a shaft having a wedge tip through the catheter to radially deflect the electrodes on the working end of the catheter outwardly so as to place the electrode in apposition with the vein at the treatment site.
Claim 78
Dependent Claim
38 words
The method of claim 64, wherein the step of positioning further includes the step of providing an external tourniquet to compress the vein so that the electrode is placed in apposition with the vein at the treatment site.
Claim 79
Dependent Claim
40 words
The method of claim 64, wherein the step of positioning further includes the step of moving a bent deflection wire through the catheter to deflect the catheter and the electrode to one side of the vein at the treatment site.
Claim 80
Dependent Claim
50 words
The method of claim 64, wherein the step of positioning further includes the step of actuating a deflection wire on one side of the catheter so as to move the catheter and the electrode on the side of the catheter opposite the deflection wire to one side of the vein.
Claim 81
Dependent Claim
50 words
The method of claim 64, wherein the step of positioning further includes the step of inflating a balloon on one side of the catheter so as to move the catheter and the electrode on the other side of the catheter to one side of the vein at the treatment site.
Claim 82
Dependent Claim
31 words
The method of claim 64, wherein the step of positioning further includes the step of inflating a balloon on the catheter to center the catheter and the electrode within the vein.
Claim 83
Dependent Claim
56 words
The method of claim 64, wherein the step of positioning further includes the step of inflating a balloon on the catheter to occlude the vein so as to limit blood flow within the vein between the balloon and the venous valve of the vein, wherein the working end is between the balloon and the venous valve.
Claim 84
Dependent Claim
29 words
The method of claim 64, wherein the step of applying radiant high frequency energy further includes the step of limiting the shrinkage of the vein to a selected diameter.
Claim 85
Dependent Claim
84 words
The method of claim 80, wherein the step of positioning the electrode further includes the step of placing the electrode into apposition with the vein by increasing an effective diameter of the catheter, wherein the shrinkage of the vein reduces the effective diameter of the catheter; and the step of limiting the shrinkage of the vein further includes the step of preventing the effective diameter of the catheter from being reduced to less than a selected diameter representing the sufficient shrinkage of the vein.
Claim 86
Dependent Claim
44 words
The method of claim 65, wherein the step of applying radiant energy further includes the step of limiting the shrinkage of the vein by inflating a balloon to a selected diameter; wherein the inflated balloon prevents shrinkage of the vein beyond the selected diameter.
Claim 87
Dependent Claim
76 words
The method of claim 65, wherein the step of positioning the electrode further includes the step of placing the electrode into apposition with the vein wall; and the step of applying energy further includes the step of reducing an effective diameter of the catheter in a controlled manner so as to maintain apposition with the vein wall as the vein wall shrinks until a diameter for the vein is achieved, wherein the vein continues to function.
Claim 88
Dependent Claim
33 words
The method of claim 65, wherein the step of applying energy further includes the step of limiting the shrinkage of the vein to the fixed diameter of the catheter at the working end.
Claim 89
Dependent Claim
36 words
The method of claim 65, wherein the step of applying radiant high frequency energy further includes the step of controlling the frequency of the energy from the electrode so as to minimize coagulation in the vein.
Claim 90
Dependent Claim
43 words
The method of claim 65, wherein the step of applying radiant high frequency energy further includes the step of controlling the frequency of the energy from the electrode so as to control the spread of heating at the treatment site of the vein.
Claim 91
Dependent Claim
61 words
The method of claim 65, wherein the electrode includes a plurality of longitudinal electrodes, and the step of applying the high frequency energy further includes the step of providing the high frequency energy to the longitudinal electrodes along the circumference of the working end of the catheter; wherein the vein is shrunk circumferentially and axial shrinkage of the vein is minimized.
Claim 92
Dependent Claim
42 words
The method of claim 65, wherein the electrode is a ring electrode, and the step of applying the high frequency energy further includes the step of providing the high frequency energy to the ring electrode at the working end of the catheter.
Claim 93
Dependent Claim
44 words
The method of claim 65, wherein the step of applying the high frequency energy further includes the step of providing an inert cap at the working end of the catheter past the electrode to prevent vein shrinkage past the working end of the catheter.
Claim 94
Dependent Claim
37 words
The method of claim 65, wherein the step of applying energy further includes the step of providing the catheter with a bend towards the working end; and rotating the catheter so as to create a stirring effect.
Claim 95
Dependent Claim
22 words
The method of claim 65, further comprising the step of delivering a cooling fluid to the treatment site for preventing thermal coagulation.
Claim 96
Dependent Claim
18 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein.
Claim 97
Dependent Claim
20 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein using fluoroscopy.
Claim 98
Dependent Claim
21 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein using ultrasound imaging.
Claim 99
Dependent Claim
21 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein using pulse-echo ultrasound.
Claim 100
Dependent Claim
21 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein using external ultrasound.
Claim 101
Dependent Claim
26 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein by measuring the impedance of the treatment site.
Claim 102
Dependent Claim
26 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein by measuring the temperature of the treatment site.
Claim 103
Dependent Claim
21 words
The method of claim 65, further comprising the step of determining the extent of shrinkage of the vein using an angioscope.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-03-14 | 2003-09-13 | 2004-03-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-03-14 | 2007-09-13 | 2008-03-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-03-14 | 2011-09-13 | 2012-03-14 | $7700.00 | Window Closed / Lapsed |