US5472441A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for treating cancer and non-malignant tumors and methods
Assignee: Angiodynamics Inc
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Filing: 1994-03-11
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Granted: 1995-12-05
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Expires: 2014-03-11
Abstract
Abstract A method of this invention for treating body tissues containing cancerous cells or non-malignant tumors with RF ablation, alone or in combination with systemic or localized chemotherapy comprising introducing a stylet comprising an electrode surface and a sleeve longitudinally moveable thereon into the vicinity of the body tissues, retracting the sleeve from a portion of the electrode surface, and supplying RF power to the electrode surface sufficient to heat the tissue to a temperature of above about 45° C. for a time to cause reduction of tissue mass in the vicinity of the electrode. The RF power supplied to the electrode surface is sufficient to effect a desiccated fluid diffusion barrier capsule surrounding the body tissue being treated. The stylet can include a hollow tube having fluid distribution ports therein, and the method can include the step of passing fluid through one or more distribution ports into the body tissue being treated. The fluid can be saline or a chemotherapeutic fluid such as liquid or gas containing a cytotoxic agent, for example. The fluid can be administered in a variety of procedures. The fluid can be passed through a distribution port into the body tissue before, during and/or after the RF power is supplied to the electrode surface, for example. Preferably, the fluid is introduced after a barrier capsule has been formed. The devices comprises electrodes havming a hollow core and a closed sharpened distal tip. The electrode has a plurality of fluid distribution ports therein for distribution of fluid treatment agents into the tissue.
Inventors
- 👤 Stuart D. Edwards
- 👤 Ronald G. Lax
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:29
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1477; A61B18/1482; A61B18/18; A61B18/1815; A61N; A61N5/00; A61N5/02; A61N5/04; A61N5/045; A61B18/1402; A61B18/1492; A61B2018/00005; A61B2018/00011; A61B2018/00053; A61B2018/00184; A61B2018/00196; A61B2018/00315; A61B2018/00452; A61B2018/00476; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00702; A61B2018/00708; A61B2018/00726; A61B2018/00761; A61B2018/00773; A61B2018/00779; A61B2018/00791; A61B2018/00875; A61B18/1206; A61B2018/124; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1405; A61B2018/1425; A61B2018/1435; A61B18/16; A61B2018/162; A61B2218/00; A61B2218/001; A61B2218/002; A61M; A61M25/00; A61M25/0067; A61M25/0068; A61M25/007
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
128 words
A method for ablating tissue at a tissue treatment site where dehydration of tissue at the tissue treatment site is reduced, the method comprising the steps of: a) introducing an Rf ablation device into a tissue treatment site, the device including a hollow tubular Rf electrode having a closed, sharpened distal tip, an electrode conductive surface for conducting Rf ablation, and a plurality of fluid distribution ports distributed along the length of the electrode for delivering chemotherapeutic agents to the tissue treatment site; and b) supplying Rf power to the electrode to produce a diffusion barrier capsule at the tissue treatment site wherein the position of the electrode relative to the tissue treatment site is varied sufficiently frequently to reduce dehydration of tissue at the tissue treatment site.
Claim 2
Independent Claim
128 words
A method for ablating tissue at a tissue treatment site where dehydration of tissue at the tissue treatment site is reduced, the method comprising the steps of: a) introducing an Rf ablation device into a tissue treatment site, the device including a hollow tubular Rf electrode having a closed, sharpened distal tip, an electrode conductive surface for conducting Rf ablation, and a plurality of fluid distribution ports distributed along the length of the electrode for delivering chemotherapeutic agents to the tissue treatment site; and b) supplying Rf power to the electrode to produce a diffusion barrier capsule at the tissue treatment site wherein the position of the electrode relative to the tissue treatment site is varied sufficiently frequently to reduce dehydration of tissue at the tissue treatment site.
Claim 3
Dependent Claim
30 words
The method according to claim 1, further including the step of passing fluid through the fluid distribution ports during ablation to reduce dehydration of tissue at the tissue treatment site.
Claim 4
Dependent Claim
30 words
The method according to claim 1 further including the step of varying the position of the electrode relative to the tissue treatment site by at least 1 mm during ablation.
Claim 5
Dependent Claim
29 words
The method according to claim 2 further including the step of varying the position of the electrode relative to the tissue treatment site between about 1 and 3 mm.
Claim 6
Dependent Claim
30 words
The method according to claim 1 further including the step of varying the position of the electrode relative to the tissue treatment site along a longitudinal axis of the electrode.
Claim 7
Dependent Claim
47 words
The method according to claim 1 wherein the device further includes an electrode position modifier and further including the step of varying the position of the electrode relative to the tissue treatment site sufficiently frequently during ablation to reduce dehydration of tissue at the tissue treatment site.
Claim 8
Dependent Claim
30 words
The method according to claim 5 further including the step of passing fluid through the fluid distribution ports during ablation to reduce dehydration of tissue at the tissue treatment site.
Claim 9
Dependent Claim
31 words
The method according to claim 7 further including the step of varying the position of the electrode relative to the tissue treatment site is by at least 1 mm during ablation.
Claim 10
Dependent Claim
30 words
The method according to claim 8 further including the step of varying the position of the electrode relative to the tissue treatment site by between about 1 and 3 mm.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-12-04 | 1999-06-05 | 1999-12-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-12-04 | 2003-06-05 | 2003-12-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-12-04 | 2007-06-05 | 2007-12-05 | $7700.00 | Window Closed / Lapsed |