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US5843172A Expired / Lapsed US ⏱️ 0.0 years remaining

Porous medicated stent

Assignee: Abbott Cardiovascular Systems Inc
•
Filing: 1997-04-15
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Granted: 1998-12-01
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Expires: 2017-04-15
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Abstract

Abstract A medicated prosthesis, such as a stent, is deployed in a human vessel. A metallic stent has a plurality of pores in the metal which are loaded with medication. When the stent is implanted into the vasculature of a patient, the medication in the stent dissipates into the tissue of the vasculature proximate the stent. The stent may be formed from a porous metal in the form of a wire, tube, or metal sheet. The present invention also includes a method of treating vasculature disease by delivering medication to the site of the vascular disease including the step of deploying a metal stent having a plurality of pores in the stent and further having medication in the pores and delivering the stent to the site of vasculature disease.

Inventors

  • 👤 John Y. Yan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:00
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/92; A61L; A61L31/00; A61L31/02; A61L31/022; A61L31/08; A61L31/10; A61L31/14; A61L31/146; A61L31/16; A61F2/0077; A61F2/86; A61F2/90; A61F2/91; A61F2210/00; A61F2210/0076; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2250/0068; A61L2300/00; A61L2300/40; A61L2300/416; A61L2300/42; A61L2300/60; A61L2300/602

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 67 words
A medicated stent comprising: a metallic stent configured to maintain patency of a human vessel, the metallic stent having a plurality of porous cavities; a therapeutic medication loaded into the porous cavities of the metallic stent; and a polymeric coating over the surface of the metallic stent wherein the medication in the pores of the stent is a first medication, wherein the coating contains a second medication.
Claim 2
Dependent Claim 67 words
A medicated stent comprising: a metallic stent configured to maintain patency of a human vessel, the metallic stent having a plurality of porous cavities; a therapeutic medication loaded into the porous cavities of the metallic stent; and a polymeric coating over the surface of the metallic stent wherein the medication in the pores of the stent is a first medication, wherein the coating contains a second medication.
Claim 3
Dependent Claim 20 words
The stent of claim 1, wherein the coating is approximately in the range of 0.0001 inches to 0.002 inches thick.
Claim 4
Dependent Claim 11 words
The stent of claim 1, wherein the coating is a bio-polymer.
Claim 5
Dependent Claim 13 words
The stent of claim 3, wherein the bio-polymer is polylactic acid or fibrin.
Claim 6
Dependent Claim 12 words
The stent of claim 1, wherein the coating is a synthetic polymer.
Claim 7
Dependent Claim 23 words
The stent of claim 5, wherein the coating of the group comprising polyurethane, polyethylene teraphthalate, polyethylene, ethlene vinyl acetate, silicone or polyethylene oxide.
Claim 8
Dependent Claim 11 words
The stent of claim 1, wherein the coating is a hydrogel.
Claim 9
Dependent Claim 12 words
The stent of claim 1, wherein the coating is a heparin coating.
Claim 10
Dependent Claim 17 words
The stent of claim 1, wherein the coating is an ionic heparin coating that is ionic bonded.
Claim 11
Dependent Claim 15 words
The stent of claim 1, wherein the coating is an end point attached heparin coating.
Claim 12
Dependent Claim 13 words
The stent of claim 1, wherein the coating is a photolinked heparin coating.
Claim 13
Dependent Claim 25 words
The stent of claim 1, wherein the coating is porous and the pores are sized to permit controlled release of the medication through the pores.
Claim 14
Dependent Claim 17 words
The stent of claim 1, wherein the coating is capable of being dissolved by the body fluids.
Claim 15
Dependent Claim 17 words
The stent of claim 1, wherein the coating is configured to reduce the porosity of the stent.
Claim 16
Dependent Claim 18 words
The stent of claim 1, wherein the coating is configured to improve the blood compatibility of the stent.
Claim 17
Dependent Claim 13 words
The stent of claim 1, wherein the first medication is an antithrombogenic material.
Claim 18
Dependent Claim 20 words
The stent of claim 16, wherein the first medication is of the group comprising heparin, ticlopodine, coumadin, dipyridamole, aspirin, forskolin.
Claim 19
Dependent Claim 16 words
The stent of claim 16, wherein the first medication is an GPII b III a blocker.
Claim 20
Dependent Claim 12 words
The stent of claim 16, wherein the first medication is an anti-coagulant.
Claim 21
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is an anti-fibrin agent.
Claim 22
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is an anti-thrombin agent.
Claim 23
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is an anti-platelet agent.
Claim 24
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is an anti-proliferative agent.
Claim 25
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is a radioactive material.
Claim 26
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is a vaso-active drug.
Claim 27
Dependent Claim 11 words
The stent of claim 16, wherein the first medication promotes endothelialization.
Claim 28
Dependent Claim 13 words
The stent of claim 16, wherein the first medication is an anti-inflammatory agent.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-11-30 2002-06-01 2002-12-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-11-30 2006-06-01 2006-12-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-11-30 2010-06-01 2010-12-01 $7700.00 Window Closed / Lapsed

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