US5704910A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implantable device and use therefor
Assignee: RENAMED BIOLOGICS Inc
•
Filing: 1995-06-05
•
Granted: 1998-01-06
•
Expires: 2015-06-05
Abstract
Abstract Disclosed is an implantable device for delivering a pre-selected molecule, for example, a hormone, into a mammal's systemic circulation. The device comprises a blood permeable element that can be anchored to an inner wall of an intact blood vessel. The device also comprises a capsule that is held in place within the blood vessel by the anchored blood permeable element. The capsule encloses viable cells which produce and secrete the pre-selected molecule into blood passing the capsule. The invention also provides a minimally invasive method for percutaneously introducing into a preselected blood vessel the device of the invention.
Inventors
- 👤 H. David Humes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:50
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61F; A61F2/00; A61F2/01; A61F2/0105; A61F2/02; A61F2/022; A61M; A61M31/00; A61M31/002; A61F2002/016; A61F2230/00; A61F2230/0002; A61F2230/0028; A61F2230/005; A61F2230/0063; A61F2230/0067; A61K38/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
88 words
A method for percutaneously introducing into a blood vessel a device for delivering a pre-selected molecule into systemic circulation, the method comprising the steps of: (a) anchoring a blood permeable element to an inner wall of all intact blood vessel, the element when anchored permitting blood in the vessel to pass therethrough; (b) introducing at a location upstream of the dement a capsule comprising viable calls which produce and secrete the pre-selected molecule; and (c) permitting the capsule, impelled by blood flow, to be captured by the element.
Claim 2
Independent Claim
88 words
A method for percutaneously introducing into a blood vessel a device for delivering a pre-selected molecule into systemic circulation, the method comprising the steps of: (a) anchoring a blood permeable element to an inner wall of all intact blood vessel, the element when anchored permitting blood in the vessel to pass therethrough; (b) introducing at a location upstream of the dement a capsule comprising viable calls which produce and secrete the pre-selected molecule; and (c) permitting the capsule, impelled by blood flow, to be captured by the element.
Claim 3
Dependent Claim
23 words
The method of claim 1, comprising the additional step, prior to step (a), of introducing the element into the vessel via a catheter.
Claim 4
Dependent Claim
18 words
The method of claim 1 or 2, wherein the capsule is introduced into the vessel by a catheter.
Claim 5
Dependent Claim
13 words
The method of claim 3, wherein the element is anchored in a vein.
Claim 6
Dependent Claim
30 words
The method of claim 4, wherein the vein is selected from the group consisting of an inferior vena cava, a superior vena cava, a portal vein and a renal vein.
Claim 7
Dependent Claim
12 words
The method of claim 1, wherein the pre-selected molecule is a hormone.
Claim 8
Dependent Claim
18 words
The method of claim 6, wherein the hormone is selected from the group consisting of erythropoietin and insulin.
Claim 9
Dependent Claim
22 words
The method of claim 1, wherein the element comprises a plurality of filaments anchorable to the inner wall of the blood vessel.
References Cited (Backward Citations)
US3313289A
Cited
US3952747A
Cited
US4309776A
Cited
US4393133A
Cited
US4378016A
Cited
US4586922A
Cited
US4479796A
Cited
US4494531A
Cited
US4793825A
Cited
DE3447202A1
Cited
US4771773A
Cited
US4793348A
Cited
US4781177A
Cited
US5104399A
Cited
US5026365A
Cited
US4817600A
Cited
US5182111A
Cited
WO1989004655A1
Cited
US5487739A
Cited
EP0341039A1
Cited
US5164186A
Cited
US4994069A
Cited
WO1990006997A1
Cited
US5152777A
Cited
US5059205A
Cited
DE3941873A1
Cited
US5053008A
Cited
US5147379A
Cited
WO1992015676A1
Cited
US5350398A
Cited
US5314471A
Cited
WO1993006878A1
Cited
US5383892A
Cited
US5304120A
Cited
EP0598635A1
Cited
EP0604022A1
Cited
US5383887A
Cited
WO1994015583A1
Cited
US5443508A
Cited
WO1995000654A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-01-05 | 2001-07-07 | 2002-01-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-01-05 | 2005-07-07 | 2006-01-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-01-05 | 2009-07-07 | 2010-01-06 | $7700.00 | Window Closed / Lapsed |