Patent US1890513A successfully refreshed from Google Patents.
US4479796A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Self-regenerating drug administration device
Assignee: Medtronic Inc
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Filing: 1982-11-15
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Granted: 1984-10-30
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Expires: 2002-11-15
Abstract
Abstract An implantable dispenser for infusing a desired drug into the blood stream. The dispenser is adapted to be spliced into a blood vessel so that blood flows freely through it. Within the dispenser is a replaceable biomass cartridge containing a colony of microorganisms which produce the drug.
Inventors
- 👤 Michael J. Kallok
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:19
CPC Classifications
A; A61; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
132 words
An implantable drug dispenser comprising: a dispenser body having a proximal end and a distal end and a bore running from said proximal to said distal end, said proximal end provided with a first attachment means for attaching said proximal end to a blood vessel, said distal end provided with a second attachment means for attaching said distal end to a blood vessel, said dispenser body further comprised of a cartridge comprising a cartridge body having a proximal end, a distal end, and a central bore connecting said proximal end to said distal end, the bore of said cartridge body in fluid communication with the bore of said dispenser body, wherein said cartridge further comprises retaining means for retaining a colony of drug producing microorganisms within said bore of said dispenser body.
Claim 2
Dependent Claim
132 words
An implantable drug dispenser comprising: a dispenser body having a proximal end and a distal end and a bore running from said proximal to said distal end, said proximal end provided with a first attachment means for attaching said proximal end to a blood vessel, said distal end provided with a second attachment means for attaching said distal end to a blood vessel, said dispenser body further comprised of a cartridge comprising a cartridge body having a proximal end, a distal end, and a central bore connecting said proximal end to said distal end, the bore of said cartridge body in fluid communication with the bore of said dispenser body, wherein said cartridge further comprises retaining means for retaining a colony of drug producing microorganisms within said bore of said dispenser body.
Claim 3
Dependent Claim
30 words
An implantable drug dispenser according to claim 1 wherein said retaining means comprises a semipermeable membrane of sufficient permeability to permit passage of nutrients, microorganism waste, and said drug therethrough.
Claim 4
Dependent Claim
27 words
An implantable drug dispenser according to claim 2 wherein said semipermeable membrane takes the form of a closed capsule for encapsulating said colony of drug producing microorganisms.
Claim 5
Dependent Claim
180 words
An implantable drug dispenser comprising: a dispenser body having a proximal end and a distal end and a bore running from said proximal to said distal end, said proximal end provided with a first attachment means for attaching said proximal end to a blood vessel, said distal end provided with a second attachment means for attaching said distal end to a blood vessel; and a retaining means for retaining a colony of drug producing microorganisms within the bore of said dispenser body, comprising a semipermeable membrane of sufficient permeability to permit passage of nutrients, microorganism waste, and said drug therethrough, taking the form of a closed capsule for encapsulating said coloney of drug producing microorganisms, said retaining means further comprising a first screen, spanning the bore of said dispenser body, located proximal to said capsule, said first screen having pores of sufficient size to permit passage of blood cells therethrough and a second screen, spanning the bore of said dispenser body, located distal to said capsule, said second screen having pores of sufficient size to permit passage of blood cells.
Claim 6
Dependent Claim
180 words
An implantable drug dispenser comprising: a dispenser body having a proximal end and a distal end and a bore running from said proximal to said distal end, said proximal end provided with a first attachment means for attaching said proximal end to a blood vessel, said distal end provided with a second attachment means for attaching said distal end to a blood vessel; and a retaining means for retaining a colony of drug producing microorganisms within the bore of said dispenser body, comprising a semipermeable membrane of sufficient permeability to permit passage of nutrients, microorganism waste, and said drug therethrough, taking the form of a closed capsule for encapsulating said coloney of drug producing microorganisms, said retaining means further comprising a first screen, spanning the bore of said dispenser body, located proximal to said capsule, said first screen having pores of sufficient size to permit passage of blood cells therethrough and a second screen, spanning the bore of said dispenser body, located distal to said capsule, said second screen having pores of sufficient size to permit passage of blood cells.
Claim 7
Dependent Claim
65 words
An implantable drug dispenser according to claim 4 wherein said dispenser body is further comprised of a cartridge comprising a cartridge body having a proximal end, a distal end, and a central bore connecting said proximal end to said distal end, the bore of said cartridge body in fluid communication with the bore of said dispenser body, wherein said cartridge further comprises said retaining means.
Claim 8
Dependent Claim
29 words
An implantable drug dispenser according to claim 1 or claim 2 or claim 3 or claim 4 or claim 5 wherein said cartridge is removable from said dispenser body.
Claim 9
Dependent Claim
55 words
An implantable drug dispenser according to claim 6 wherein said dispenser body further comprises a proximal dispenser body segment including the proximal end of said dispenser body and a distal dispenser body segment including the distal end of said dispenser body, said proximal dispenser body segment and said distal dispenser body segment enclosing said cartridge.
Claim 10
Dependent Claim
22 words
An implantable drug dispenser according to claim 7 wherein said proximal dispenser body segment is removeable from said distal dispenser body segment.
Claim 11
Dependent Claim
32 words
An implantable drug dispenser according to claim 8 wherein the bore of said cartridge and the bore of said dispenser body are continuous when said cartridge is installed in said dispenser body.
Claim 12
Dependent Claim
35 words
An implantable drug dispenser according to claim 9 wherein the bore of said dispenser body is flared at the proximal end of said dispenser body and flared at the distal end of said dispenser body.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-10-30 | 1988-04-30 | 1988-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-10-30 | 1992-04-30 | 1992-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-10-30 | 1996-04-30 | 1996-10-30 | $7700.00 | Window Closed / Lapsed |