US4309776A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Intravascular implantation device and method of using the same
Assignee: Individual
•
Filing: 1980-05-13
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Granted: 1982-01-12
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Expires: 2000-05-13
Abstract
Abstract An intravascular device having a chamber for containing transplanted cells. The device is adapted to be implanted in a wall of a blood vessel with a porous chamber-forming wall of the chamber providing an interface between the cells in the chamber and the blood in the vessel. The chamber-forming wall has a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells. The device may also be implanted between an artery and a vein in a wall of each so as to act as a sieve between the artery and vein subject to the differential pressure therebetween. A method is also disclosed for employing the device to introduce hormonal components into the blood stream.
Inventors
- 👤 Ramon Berguer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:10
CPC Classifications
A; A61; A61M; A61M37/00; A61M37/0069; A61F; A61F2/00; A61F2/02; A61F2/022; A61F2/04; A61F2/06; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
75 words
An intravascular device having a chamber for containing transplanted cells and having outwardly extending peripheral flange means designed and shaped for suturing in an opening made in the wall of a blood vessel with a porous chamber-forming wall thereof providing an interface between the cells in the chamber and the blood in the vessel, said porous chamber-forming wall having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells.
Claim 2
Dependent Claim
75 words
An intravascular device having a chamber for containing transplanted cells and having outwardly extending peripheral flange means designed and shaped for suturing in an opening made in the wall of a blood vessel with a porous chamber-forming wall thereof providing an interface between the cells in the chamber and the blood in the vessel, said porous chamber-forming wall having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells.
Claim 3
Dependent Claim
129 words
An intravascular device having a chamber for containing transplanted cells and adapted to be implanted between an artery and a vein and having outwardly extending peripheral flange means designed and shaped for suturing in an opening made in a wall of each with a porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the artery and another porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the vein, said porous chamber-forming walls each having a pore size permitting continous diffusion of hormonal components therethrough but blocking the diffusion of cells so that said device acts as a sieve between said artery and vein subject to the differential pressure therebetween.
Claim 4
Dependent Claim
129 words
An intravascular device having a chamber for containing transplanted cells and adapted to be implanted between an artery and a vein and having outwardly extending peripheral flange means designed and shaped for suturing in an opening made in a wall of each with a porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the artery and another porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the vein, said porous chamber-forming walls each having a pore size permitting continous diffusion of hormonal components therethrough but blocking the diffusion of cells so that said device acts as a sieve between said artery and vein subject to the differential pressure therebetween.
Claim 5
Dependent Claim
35 words
An intravascular device as defined in claim 1 or 2, wherein the pores in said chamber-forming wall or walls have a diameter in a range on the order of about 0.2 microns to 25 microns.
Claim 6
Dependent Claim
20 words
An intravascular device as defined in claim 1 or 2 wherein said device is made of a biocompatible, non-thrombus-inducing material.
Claim 7
Dependent Claim
17 words
An intravascular device as defined in claim 1 or 2, wherein said device is made of polytetrafluoroethylene.
Claim 8
Dependent Claim
39 words
An intravascular device as defined in claim 1 or 2, wherein other walls of said device not in contact with the blood will become effectively non-porous once they are healed and thereby block diffusion of cellular and hormonal components.
Claim 9
Dependent Claim
50 words
An intravascular device as defined in claim 1, wherein said device is in the form of a considerably flattened and somewhat elongated hollow body, said flange means comprising a peripheral flange on said body about a line of maximum circumference thereof for attachment to a wall of the blood vessel.
Claim 10
Dependent Claim
49 words
An intravascular device as defined in claim 2, wherein said device is in the form of a hollow body, said flange means comprising annular flanges on said body in spaced relation to one another for attachment respectively to a wall of the artery and a wall of the vein.
Claim 11
Dependent Claim
23 words
An intravascular device as defined in claim 1 or 2, including a tube communicating with said chamber for the introduction of hormone-producing cells.
Claim 12
Independent Claim
69 words
A method for introducing hormonal components into the blood stream comprising implanting in a wall of a blood vessel a device having a chamber containing transplanted cells with a porous chamber-forming wall thereof providing an interface between the cells in the chamber and the blood in the vessel, said porous chamber-forming wall having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells.
Claim 13
Independent Claim
69 words
A method for introducing hormonal components into the blood stream comprising implanting in a wall of a blood vessel a device having a chamber containing transplanted cells with a porous chamber-forming wall thereof providing an interface between the cells in the chamber and the blood in the vessel, said porous chamber-forming wall having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells.
Claim 14
Independent Claim
118 words
A method for introducing hormonal components into the blood stream comprising implanting between an artery and a vein in a wall of each a device having a chamber containing transplanted cells with a porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the artery and another porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the vein, said porous chamber-forming walls each having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells so that said device acts as a sieve between said artery and vein subject to the differential pressure therebetween.
Claim 15
Independent Claim
118 words
A method for introducing hormonal components into the blood stream comprising implanting between an artery and a vein in a wall of each a device having a chamber containing transplanted cells with a porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the artery and another porous chamber-forming wall of said device providing an interface between the cells in said chamber and the blood in the vein, said porous chamber-forming walls each having a pore size permitting continuous diffusion of hormonal components therethrough but blocking the diffusion of cells so that said device acts as a sieve between said artery and vein subject to the differential pressure therebetween.
Claim 16
Dependent Claim
34 words
A method as defined in claim 10 or 11, wherein the pores in said chamber-forming wall or walls have a diameter in a range on the order of about 0.2 microns to 25 microns.
Claim 17
Dependent Claim
19 words
A method as defined in claim 10 or 11, wherein said device is made of a biocompatible, non-thrombus-inducing material.
Claim 18
Dependent Claim
16 words
A method as defined in claim 10 or 11, wherein said device is made of polytetrafluoroethylene.
Claim 19
Dependent Claim
32 words
A method as defined in claim 10 or 11, wherein other walls of said device not in contact with the blood are effectively non-porous to block diffusion of cellular and hormonal components.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-01-11 | 1985-07-13 | 1986-01-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-01-11 | 1989-07-13 | 1990-01-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-01-11 | 1993-07-13 | 1994-01-12 | $7700.00 | Window Closed / Lapsed |