US5645084A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for spinal fusion without decortication
Assignee: SDGI Holdings Inc
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Filing: 1995-06-07
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Granted: 1997-07-08
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Expires: 2015-06-07
Abstract
Abstract Surgical procedures for stabilizing a spine include exposing a portion of each of adjacent vertebrae requiring fusion and placing an osteoinductive material within an area between the portions of the adjacent vertebrae in contact with the cortical bone of the portions. In another aspect, surgical procedures for stabilizing a spine are provided which include exposing a portion of each of adjacent vertebrae requiring fusion, adding an osteoinductive cytokine to a carrier material and placing the carrier material between the portions of the adjacent vertebrae in contact with the cortical bone of the portions.
Inventors
- 👤 William F. McKay
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:43
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/227; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/44; A61F2/4455; A61L31/00; A61L31/04; A61L31/043; A61L31/047; A61F2/442
Claims Analysis
Total Claims: 31
Claim 1
Independent Claim
62 words
A surgical procedure for stabilizing, vertebrae in a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae; and placing an osteoinductive material within an area between the portions of the adjacent vertebrae in contact with only the cortical bone of the portions.
Claim 2
Dependent Claim
62 words
A surgical procedure for stabilizing, vertebrae in a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae; and placing an osteoinductive material within an area between the portions of the adjacent vertebrae in contact with only the cortical bone of the portions.
Claim 3
Dependent Claim
23 words
The surgical procedure of claim 1 wherein said placing step includes placing strips containing the osteoinductive material within the area between the portions.
Claim 4
Dependent Claim
17 words
The surgical procedure of claim 1 wherein said portions are at a posterior aspect of the spine.
Claim 5
Dependent Claim
17 words
The surgical procedure of claim 1 wherein said portions are the transverse processes of the adjacent vertebrae.
Claim 6
Dependent Claim
18 words
The surgical procedure of claim 1 wherein said portions are the adjacent vertebral endplates of the adjacent vertebrae.
Claim 7
Dependent Claim
14 words
The surgical procedure of claim 1 wherein said osteoinductive material includes an osteoinductive cytokine.
Claim 8
Dependent Claim
23 words
The surgical procedure of claim 1 wherein said placing step includes placing sheets containing the osteoinductive material within the area between the portions.
Claim 9
Dependent Claim
24 words
The surgical procedure of claim 1 wherein said placing step includes placing an implant containing said osteoinductive material within the area between the portions.
Claim 10
Dependent Claim
17 words
The surgical procedure of claim 3 wherein said portions are the spinous processes of the adjacent vertebrae.
Claim 11
Dependent Claim
20 words
The surgical procedure of claim 3 wherein said portions are within the neural arch of each of the adjacent vertebrae.
Claim 12
Dependent Claim
15 words
The surgical procedure of claim 6 wherein said osteoinductive material includes a bone morphogenic protein.
Claim 13
Dependent Claim
33 words
The surgical procedure of claim 6 wherein said osteoinductive material further includes a carrier selected from the group consisting of calcium sulfate, polylactic acids, polyanhydrides, collagen, calcium phosphate ceramics and polymeric acrylic esters.
Claim 14
Dependent Claim
31 words
The surgical procedure of claim 11 wherein said bone morphogenic protein is selected from the group consisting of BMP-1, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-6, BMP-7, BMP-8, BMP-9, BMP-10, and BMP-11.
Claim 15
Dependent Claim
13 words
The surgical procedure of claim 13 wherein said bone morphogenic protein is BMP-2.
Claim 16
Dependent Claim
15 words
The surgical procedure of claim 12 wherein said carrier is an open-porosity polylactic acid polymer.
Claim 17
Dependent Claim
12 words
The surgical procedure of claim 12 wherein said carrier includes tricalcium phosphate.
Claim 18
Dependent Claim
15 words
The surgical procedure of claim 16 wherein said carrier is a biphasic tricalcium phosphate/hydroxyapatite ceramic.
Claim 19
Dependent Claim
11 words
The surgical procedure of claim 12 wherein said carrier includes collagen.
Claim 20
Dependent Claim
12 words
The surgical procedure of claim 18 wherein said carrier is fibrillar collagen.
Claim 21
Dependent Claim
23 words
The surgical procedure of claim 19 wherein said osteoinductive material is an admixture of the osteoinductive cytokine and a polymeric acrylic ester carrier.
Claim 22
Dependent Claim
13 words
The surgical procedure of claim 20 wherein the polymeric acrylic ester is polymethylmethacrylate.
Claim 23
Dependent Claim
49 words
A surgical procedure for stabilizing a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae in the spine; and injecting an osteoinductive material into the disc space between the adjacent vertebrae and in contact with only the cortical bone of the portions.
Claim 24
Dependent Claim
49 words
A surgical procedure for stabilizing a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae in the spine; and injecting an osteoinductive material into the disc space between the adjacent vertebrae and in contact with only the cortical bone of the portions.
Claim 25
Dependent Claim
65 words
A surgical procedure for stabilizing a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae; adding an osteoinductive cytokine to a carrier material; and placing the carrier material between said portions of the adjacent vertebrae in contact with only the nondecorticated bone of the portions.
Claim 26
Dependent Claim
65 words
A surgical procedure for stabilizing a spine, comprising the steps of: exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae; adding an osteoinductive cytokine to a carrier material; and placing the carrier material between said portions of the adjacent vertebrae in contact with only the nondecorticated bone of the portions.
Claim 27
Dependent Claim
22 words
The surgical procedure of claim 23 wherein said adding step includes injecting said cytokine into said carrier material before said placing step.
Claim 28
Dependent Claim
22 words
The surgical procedure of claim 23 wherein said adding step includes injecting said cytokine into said carrier material after said placing step.
Claim 29
Dependent Claim
17 words
The surgical procedure of claim 23 wherein said portions are the transverse processes of the adjacent vertebrae.
Claim 30
Dependent Claim
15 words
The surgical procedure of claim 23 wherein said osteoinductive cytokine includes a bone morphogenic protein.
Claim 31
Dependent Claim
31 words
The surgical procedure of claim 27 wherein said bone morphogenic protein is selected from the group consisting of BMP-1, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-6, BMP-7, BMP-8, BMP-9, BMP-10, and BMP-11.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-07-07 | 2001-01-06 | 2001-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-07-07 | 2005-01-06 | 2005-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-07-07 | 2009-01-06 | 2009-07-08 | $7700.00 | Window Closed / Lapsed |