US5106748A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dna sequences encoding 5 proteins
Assignee: Genetics Institute LLC
•
Filing: 1989-06-23
•
Granted: 1992-04-21
•
Expires: 2009-06-23
Abstract
Abstract Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
Inventors
- 👤 John M. Wozney
- 👤 Vicki A. Rosen
- 👤 Elizabeth A. Wang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 07:59
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/63; C12N15/79; C12N15/85; A; A61; A61L; A61L24/00; A61L24/04; A61L24/043; A61L27/00; A61L27/14; A61L27/22; A61L27/227; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/51; A61K; A61K38/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
77 words
An isolated DNA molecule having a sequence encoding a BMP-5 protein which is characterized by the ability to induce the formation of cartilage and/or bone said DNA comprising the DNA sequence selected from the group consisting of (a) nucleotide #1 to #102 of FIG. 3; (b) nucleotide #1665 to #2060 of FIG. 4; (c) nucleotide #699 to #2060 of FIG. 4; and (d) naturally occurring allelic sequences and equivalent degenerative condon sequences of (a), (b), and (c).
Claim 2
Dependent Claim
77 words
An isolated DNA molecule having a sequence encoding a BMP-5 protein which is characterized by the ability to induce the formation of cartilage and/or bone said DNA comprising the DNA sequence selected from the group consisting of (a) nucleotide #1 to #102 of FIG. 3; (b) nucleotide #1665 to #2060 of FIG. 4; (c) nucleotide #699 to #2060 of FIG. 4; and (d) naturally occurring allelic sequences and equivalent degenerative condon sequences of (a), (b), and (c).
Claim 3
Dependent Claim
10 words
A host cell transfomred with a DNA of claim 1.
Claim 4
Dependent Claim
18 words
A vector comprising a DNA sequence of claim 1 in operative association with an expressio control sequence therefor.
Claim 5
Dependent Claim
10 words
A host cell transformed with a vector of claim 3.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-04-21 | 1995-10-21 | 1996-04-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-04-21 | 1999-10-21 | 2000-04-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-04-21 | 2003-10-21 | 2004-04-21 | $7700.00 | Window Closed / Lapsed |