US5554120A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polymer blends for use in making medical devices including catheters and balloons for dilatation catheters
Assignee: Abbott Cardiovascular Systems Inc
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Filing: 1994-07-25
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Granted: 1996-09-10
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Expires: 2014-07-25
Abstract
Abstract A combination of polymeric components provides desired characteristics in forming medical instruments such as catheters and balloons for dilatation catheters. For example, a balloon material is formed from a blend of polymeric components, including a first crystalline polymeric component and a second softening polymeric component. Where the first two components are generally incompatible, the balloon material can also include a third compatibilizing agent to facilitate blending the first two polymeric components together. The first polymeric component can be a branched or straight chain polyamide having a molecular weight of at least about 5000, or a polyester prepared from aromatic dicarboxylic acids having 8 to 14 carbon atoms or aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol. The second polymeric component can be a polyolefin, an ethylene copolymer, a polyester block copolymer, or a polyamide block copolymer. The third polymeric component is preferably an ethylene copolymer having the formula E/X/Y where E is ethylene; X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms; and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with the first polymeric component. The polymeric blend can be irradiated to enhance the properties of the balloon material, including significantly increasing burst pressures.
Inventors
- 👤 Ziyun Chen
- 👤 Tai Cheng
- 👤 Ketan Muni
- 👤 Udayan Patel
- 👤 Robert Saltman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:14
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1027; A61M25/1029; A61L; A61L29/00; A61L29/04; A61L29/049; C; C08; C08L; C08L67/00; C08L67/02; A61M2025/1031; A61M25/0009
Claims Analysis
Total Claims: 44
Claim 1
Independent Claim
306 words
A catheter material formed from polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 2
Dependent Claim
306 words
A catheter material formed from polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 3
Dependent Claim
64 words
The catheter material of claim 1, wherein said first polymeric component comprises about 60-77% of the total blend composition, and is selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10.
Claim 4
Dependent Claim
46 words
The catheter material of claim 1, wherein said first polymeric component is a polyester having glycol segments selected from the group consisting of ethylene glycol; 1,3-trimethylene glycol; 1,4-tetramethylene glycol; 1,6-hexamethylene glycol; 1,8-octamethylene glycol; 1,10-decamethylene glycol; 2,2-dimethyl-1,3-propane diol; 1,3-propylene glycol; 1,4-butylene glycol; neopentyl glycol and cyclohexane dimethanol.
Claim 5
Dependent Claim
23 words
The catheter material of claim 1, wherein X is selected from the group consisting of vinyl acetate, methylacrylate, butylacrylate, and methyl vinyl ether.
Claim 6
Dependent Claim
30 words
The catheter material of claim 1, wherein Y is an α, β-ethylenically unsaturated monomer containing a reactive group selected from the group consisting of epoxide, maleic anhydride, isocyanate, or oxazoline.
Claim 7
Dependent Claim
31 words
The catheter material of claim 1, wherein X is a moiety derived from at least one of alkyl acrylate, alkyl methacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof.
Claim 8
Dependent Claim
23 words
The catheter material of claim 1, wherein Y is selected from the group consisting of glycidyl methacrylate, glycidyl acrylate, maleic anhydride, and isocyanato-ethylmethacrylate.
Claim 9
Dependent Claim
31 words
The catheter material of claim 1, wherein Y is a moiety derived from at least one alkyl acrylate, alkyl methacrylate, or mixtures thereof, where the alkyl groups contain 1-8 carbon atoms.
Claim 10
Dependent Claim
24 words
The catheter material of claim 1, wherein Y is selected from the group consisting of glycidyl acrylate, glycidyl methacrylate, and epoxide containing copolymerizable monomers.
Claim 11
Dependent Claim
37 words
The catheter material of claim 1, wherein the α, β-ethylenically unsaturated mono-carboxylic acid is neutralized at least partially by at least one metal ion selected from the group consisting of sodium, zinc, magnesium, calcium, potassium, and lithium.
Claim 12
Dependent Claim
67 words
The catheter material of claim 1, wherein E is ethylene, and is 67% by weight of the compatibilizing ethylene copolymer; X is selected from the group of methylacrylate, ethylacrylate and butylacrylate, and is about 15-30% by weight of the compatibilizing ethylene copolymer; and Y is selected from the group consisting of glycidyl acrylate and glycidyl methacrylate, and is about 8% by weight of the compatibilizing ethylene copolymer.
Claim 13
Dependent Claim
12 words
The catheter material of claim 1, wherein said polymeric blend is irradiated.
Claim 14
Dependent Claim
30 words
The catheter material of claim 12, wherein said polymeric blend is irradiated using ionizing radiation generated by any of an electron beam, gamma rays, ultraviolet light, or a molecular beam.
Claim 15
Dependent Claim
23 words
The catheter material of claim 12, wherein said polymeric blend is irradiated by an electron beam in the range of about 10-100 Mrads.
Claim 16
Dependent Claim
311 words
A balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer has the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 17
Dependent Claim
311 words
A balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer has the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 18
Dependent Claim
64 words
The balloon material of claim 15, wherein said first polymeric component comprises about 60-77% of the total blend composition, and is selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10.
Claim 19
Dependent Claim
43 words
The balloon material of claim 15, wherein said first polymeric component is a glycol selected from the group consisting of ethylene glycol; 1,3-trimethylene glycol; 1,4-tetramethylene glycol; 1,6-hexamethylene glycol; 1,8-octamethylene glycol; 1,10-decamethylene glycol; 2,2-dimethyl-1,3-propane diol; 1,3-propylene glycol; 1,4-butylene glycol; neopentyl glycol and cyclohexane dimethanol.
Claim 20
Dependent Claim
23 words
The balloon material of claim 15, wherein X is selected from the group consisting of vinyl acetate, methylacrylate, butylacrylate, and methyl vinyl ether.
Claim 21
Dependent Claim
30 words
The balloon material of claim 15, wherein Y is an α, β-ethylenically unsaturated monomer containing a reactive group selected from the group consisting of epoxide, maleic anhydride, isocyanate, or oxazoline.
Claim 22
Dependent Claim
31 words
The balloon material of claim 15, wherein X is a moiety derived from at least one of alkyl acrylate, alkyl methacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof.
Claim 23
Dependent Claim
23 words
The balloon material of claim 15, wherein Y is selected from the group consisting of glycidyl methacrylate, glycidyl acrylate, maleic anhydride, and isocyanato-ethylmethacrylate.
Claim 24
Dependent Claim
31 words
The balloon material of claim 15, wherein X is a moiety derived from at least one alkyl acrylate, alkyl methacrylate, or mixtures thereof, where the alkyl groups contain 1-8 carbon atoms.
Claim 25
Dependent Claim
24 words
The balloon material of claim 15, wherein Y is selected from the group consisting of glycidyl acrylate, glycidyl methacrylate, and epoxide containing copolymerizable monomers.
Claim 26
Dependent Claim
37 words
The balloon material of claim 15, wherein the α, β-ethylenically unsaturated mono-carboxylic acid is neutralized at least partially by at least one metal ion selected from the group consisting of sodium, zinc, magnesium, calcium, potassium, and lithium.
Claim 27
Dependent Claim
67 words
The balloon material of claim 15, wherein E is ethylene, and is 67% by weight of the compatibilizing ethylene copolymer; X is selected from the group of methylacrylate, ethylacrylate and butylacrylate, and is about 15-30% by weight of the compatibilizing ethylene copolymer; and Y is selected from the group consisting of glycidyl acrylate and glycidyl methacrylate, and is about 8% by weight of the compatibilizing ethylene copolymer.
Claim 28
Dependent Claim
12 words
The balloon material of claim 15, wherein said polymeric blend is irradiated.
Claim 29
Dependent Claim
30 words
The balloon material of claim 26, wherein said polymeric blend is irradiated using ionizing radiation generated by any of an electron beam, gamma rays, ultraviolet light, or a molecular beam.
Claim 30
Dependent Claim
23 words
The balloon material of claim 26, wherein said polymeric blend is irradiated by an electron beam in the range of about 10-100 Mrads.
Claim 31
Dependent Claim
278 words
A dilatation catheter balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10; about 23-40% by weight of the total blend composition of a second polymeric component comprising an ethylene copolymer containing ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, said ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of alkylacrylate, where the alkyl group contains 1-4 carbon atoms, and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and from about 0.25% to about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 32
Dependent Claim
278 words
A dilatation catheter balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10; about 23-40% by weight of the total blend composition of a second polymeric component comprising an ethylene copolymer containing ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, said ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene, and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of alkylacrylate, where the alkyl group contains 1-4 carbon atoms, and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and from about 0.25% to about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 33
Dependent Claim
25 words
The dilatation catheter balloon material of claim 29, wherein Y is selected from the group consisting of glycidyl methacrylate, glycidyl acrylate, maleic anhydride, and isocyanato-ethylmethacrylate.
Claim 34
Dependent Claim
69 words
The dilatation catheter balloon material of claim 29, wherein E is ethylene, and is 67% by weight of the compatibilizing ethylene copolymer; X is selected from the group of methylacrylate, ethylacrylate and butylacrylate, and is about 15-30% by weight of the compatibilizing ethylene copolymer; and Y is selected from the group consisting of glycidyl acrylate and glycidyl methacrylate, and is about 8% by weight of the compatibilizing ethylene copolymer.
Claim 35
Dependent Claim
289 words
A catheter material formed from a radiation cross-linked polymeric blend, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 36
Dependent Claim
289 words
A catheter material formed from a radiation cross-linked polymeric blend, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 37
Dependent Claim
289 words
A balloon material formed from a radiation cross-linked polymeric blend, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 38
Dependent Claim
289 words
A balloon material formed from a radiation cross-linked polymeric blend, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, the ethylene copolymer having the formula E'X' or E'X'Y', where E' is ethylene and is about 60-85% by weight of the ethylene copolymer, where X' is about 15-40% by weight of the ethylene copolymer, and is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate and mixtures thereof, and Y' is selected from the group consisting of α, β-ethylenically unsaturated monocarboxylic acids, α, β-ethylenically unsaturated dicarboxylic acids, and anhydrides comprising about 0.5-15% by weight of the ethylene copolymer; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 39
Dependent Claim
299 words
A catheter material formed from polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 40
Dependent Claim
299 words
A catheter material formed from polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 41
Dependent Claim
302 words
A balloon material formed from a blend composition of polymeric components, comprising: about 60-70% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 42
Dependent Claim
302 words
A balloon material formed from a blend composition of polymeric components, comprising: about 60-70% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol selected from the group consisting of glycols having the formula HO(CH 2 ) n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000; about 23-40% by weight of the total blend composition of a second polymer component having a Shore hardness less than 75 D, said second polymeric component comprising a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and less than about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 43
Dependent Claim
238 words
A dilatation catheter balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10; about 23-40% by weight of the total blend composition of a second polymeric component comprising an ethylene copolymer containing ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and from about 0.25% to about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
Claim 44
Dependent Claim
238 words
A dilatation catheter balloon material formed from a blend composition of polymeric components, comprising: about 60-77% by weight of the total blend composition of a first polymeric component selected from the group consisting of polyethylene-terephthalate, polybutylene-terephthalate, glycol modified polyethylene-terephthalate, 1,4-cyclohexylene dimethylene terephthalate/isophthalate copolymer, linear homopolymer esters derived from aromatic dicarboxylic acids and glycols of the general formula HO(CH 2 ) n OH where n is an integer from 2 to 10; about 23-40% by weight of the total blend composition of a second polymeric component comprising an ethylene copolymer containing ethylene and at least one other monomer selected from the group consisting of α, β-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and wherein when said at least one other monomer comprises an α, β-ethylenically unsaturated monomer and is an acid containing moiety, said α, β-ethylenically unsaturated monomer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, lithium, calcium, and ammonium; and from about 0.25% to about 2.5% by weight of the total blend composition of a compatibilizing ethylene copolymer having the formula E/X/Y where E is ethylene, X is an α, β-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms, and Y is an α, β-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1999-09-10 | 2000-03-11 | 2000-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-09-10 | 2004-03-11 | 2004-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-09-10 | 2008-03-11 | 2008-09-10 | $7700.00 | Window Closed / Lapsed |