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US5385940A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of stroke with nitric-oxide releasing compounds

Assignee: General Hospital Corp
•
Filing: 1992-11-05
•
Granted: 1995-01-31
•
Expires: 2012-11-05
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Abstract

Abstract A method for treatment of stroke in a patient, involving administering to the patient a nitric oxide-releasing compound. A preferred compound of the invention is L-arginine.

Inventors

  • 👤 Michael A. Moskowitz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 15:05
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 28 words
A method for treatment of an ischemic stroke patient, comprising administering intraveneously to said patient an effective amount of a nitric oxide-releasing compound for treating the ischemic stroke.
Claim 2
Independent Claim 28 words
A method for treatment of an ischemic stroke patient, comprising administering intraveneously to said patient an effective amount of a nitric oxide-releasing compound for treating the ischemic stroke.
Claim 3
Dependent Claim 12 words
The method of claim 1, wherein the nitric oxide-releasing compound is L-arginine.
Claim 4
Dependent Claim 26 words
The method of claim 1, wherein said nitric oxide-releasing compound is administered to the patient during the time period between initiation and completion of the stroke.
Claim 5
Independent Claim 33 words
A method for treatment of an ischemic stroke patient, comprising administering intravenously to said patient an effective amount for treating the stroke of a compound which is a substrate for nitric oxide synthase.
Claim 6
Independent Claim 33 words
A method for treatment of an ischemic stroke patient, comprising administering intravenously to said patient an effective amount for treating the stroke of a compound which is a substrate for nitric oxide synthase.

References Cited (Backward Citations)

US4152425A Cited
US4981691A Cited
US4764504A Cited
US4954526A Cited
US5028627A Cited
US5039705A Cited
US5081148A Cited
US5132453A Cited
WO1992018112A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-01-30 1998-08-01 1999-01-31 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2002-01-30 2002-08-01 2003-01-31 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2006-01-30 2006-08-01 2007-01-31 $7700.00 Window Closed / Lapsed

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