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US5186181A Expired / Lapsed US ⏱️ 0.0 years remaining

Radio frequency thermotherapy

Assignee: Individual
•
Filing: 1990-07-27
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Granted: 1993-02-16
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Expires: 2010-07-27
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Abstract

Abstract An electromagnetic applicator for use in hyperthermic treatments of superficial and subcutaneous tissues employing radiators integrated in a waveguide segment which is working below the cutoff frequency and supports evanscent modes of propagation which are excited by the radiators to produce a multi-modal field of controlled intensity. Additional radiators are integrated in the same waveguide to generate directly another controlled field. The multi-modal and directly emitted field are generated with a large variety of field sizes, shapes and penetration features and are combined in many ways and in any power level ratio to provide a heating field emerging from the waveguide aperture which impinges upon tissue to be heated through a noncritical air gap thereby allowing heating of a large variety of subcutaneous tumors to temperatures causing tumor necrosis without injury to the normal fat and other access tissues. Moreover, palliative treatments may be performed on subcutaneous muscle tissues and joints and on hypertrophic tissues.

Inventors

  • 👤 Cafiero Franconi
  • 👤 Jan Vrba

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:49
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/02; A61B; A61B17/00; A61B17/42; A61B2017/4216; A61B2017/4233

Claims Analysis

Total Claims: 44
Claim 1
Independent Claim 232 words
An electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: producing an electromagnetic power source with an output level, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; positioning a below cutoff waveguide segment having one end terminated by an active treatment aperture; positioning a plurality of sets of resonant radiating elements inside said waveguide segment; positioning a first set of resonant radiating elements within said waveguide segment to substantially work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; positioning a second set of resonant radiating elements within said waveguide segment to substantially work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching said sets of radiating elements to said power source; tuning said sets of radiating elements to the frequency of said power source; controlling the output level of said power source to each of said sets of resonant radiating elements; and matching electromagnetically said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 2
Dependent Claim 232 words
An electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: producing an electromagnetic power source with an output level, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; positioning a below cutoff waveguide segment having one end terminated by an active treatment aperture; positioning a plurality of sets of resonant radiating elements inside said waveguide segment; positioning a first set of resonant radiating elements within said waveguide segment to substantially work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; positioning a second set of resonant radiating elements within said waveguide segment to substantially work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching said sets of radiating elements to said power source; tuning said sets of radiating elements to the frequency of said power source; controlling the output level of said power source to each of said sets of resonant radiating elements; and matching electromagnetically said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 3
Dependent Claim 69 words
The electromagnetic heating method as claimed in claim 1 including the steps of: inserting low loss high susceptibility ferrite materials in high H-field density regions of said waveguide segment; adjusting the position of said ferrite material within said waveguide segment to produce the required time and spatial profiles of said heating fields; and automatically controlling said matching and said tuning of said resonant radiating elements to said power source.
Claim 4
Dependent Claim 69 words
The electromagnetic heating method as claimed in claim 1 including the steps of: inserting low loss high permittivity dielectric materials in high E-field density regions of said waveguide segment; adjusting the position of said dielectric material within said waveguide segment to produce the required time and spatial profiles of said heating fields; and automatically controlling said matching and said tuning of said resonant radiating elements to said power source.
Claim 5
Dependent Claim 70 words
The electromagnetic heating method as claimed in claim 1 including the step of controlling said localized heating by: constructing said waveguide segment with an aperture cross section of variable size, shape or curvature; adjusting said waveguide aperture size, shape or curvature to produce the required time and spatial profiles of said heating fields; and automatically controlling said matching and said tuning of said resonant radiating elements to said power source.
Claim 6
Dependent Claim 50 words
The electromagnetic heating method as claimed in claim 1, wherein said matching electromagnetic of said active treatment aperture to said body tissues when said body tissues present a curved anatomic surface, includes the step of: shaping said active treatment aperture to substantially conform to said curvature of said body surface.
Claim 7
Dependent Claim 73 words
The electromagnetic heating method as claimed in claim 1 wherein said localized heating comprises the additional steps of: inserting a conductive radiation shield occluding conformally said active aperture of said waveguide segment; and cutting at least one port on said radiation shield, said port acting as a secondary source generating a port-specific heating field, said secondary field being controlled by adjusting the size, shape or position of each port on said radiation shield.
Claim 8
Dependent Claim 95 words
The electromagnetic heating method as claimed in claim 1 wherein said body tissues define a body cavity and the localized heating comprises the additional steps of: providing said waveguide segment with a cross section size and shape to match the size and shape of said body cavity; and cutting at least one port in a wall of said waveguide, each port acting as a secondary source generating port-specific heating field and adjusting the size, shape or position of each port on said wall for heating specific portions of the tissues sitting in said body cavity.
Claim 9
Dependent Claim 113 words
The electromagnetic heating method as claimed in claim 1, wherein said localized heating comprises the additional steps of: providing a principal heating field generated by said hybrid passband applicator; providing at least one auxiliary and coherent heating field generated by at least one passive auxiliary electromagnetic heating device energized by an adjustable electromagnetic coupling with said hybrid passband applicator; superimposing said principal and auxiliary heating fields preferentially over said tissues to be exposed; and controlling said adjustable electromagnetic coupling to provide a relative phase, amplitude and orientation of said principal and auxiliary heating fields to generate a positive interference pattern preferentially localized over said tissues to be exposed to produce enhanced temperature elevations.
Claim 10
Dependent Claim 26 words
The electromagnetic heating method as claimed in claim 1 wherein said body tissues to be exposed include tumors to be treated to specific therapeutic temperature elevations.
Claim 11
Dependent Claim 28 words
The electromagnetic heating method as claimed in claim 1 wherein said body tissues to be exposed include superficial musculature, subcutaneous tissues and joints and said heating produces palliation.
Claim 12
Dependent Claim 26 words
The electromagnetic heating method as claimed in claim 1 wherein said body tissue to be exposed includes the hypertrophic prostatic tissue and said heating produces palliation.
Claim 13
Dependent Claim 121 words
The electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing the tissue to an EM heating field comprising the steps of; providing a principal heating field through the generating of a hybrid passband applicator; providing at least one auxiliary and coherent heating field generated by at least one active auxiliary electromagnetic heating device energized by an independent power source; superimposing said principal heating field and said at least one auxiliary and coherent heating field over said tissues to be exposed; and controlling the relative phase, amplitude and orientation of said principal and auxiliary heating fields to generate a positive interference pattern preferentially localized over said tissues to be exposed to produce enhanced temperature elevations.
Claim 14
Dependent Claim 121 words
The electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing the tissue to an EM heating field comprising the steps of; providing a principal heating field through the generating of a hybrid passband applicator; providing at least one auxiliary and coherent heating field generated by at least one active auxiliary electromagnetic heating device energized by an independent power source; superimposing said principal heating field and said at least one auxiliary and coherent heating field over said tissues to be exposed; and controlling the relative phase, amplitude and orientation of said principal and auxiliary heating fields to generate a positive interference pattern preferentially localized over said tissues to be exposed to produce enhanced temperature elevations.
Claim 15
Dependent Claim 154 words
An electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: producing an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; positioning a below cutoff waveguide segment having one end terminated by an active treatment aperture; positioning resonant radiating means inside said waveguide segment to produce multi-modal and direct heating fields; matching said resonant radiating means to said power source; turning said resonant radiating means to the frequency of said power source; controlling output level of said power source to said resonant radiating means; and matching electromagnetically said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 16
Dependent Claim 154 words
An electromagnetic heating method for the localized heating treatment of body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: producing an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; positioning a below cutoff waveguide segment having one end terminated by an active treatment aperture; positioning resonant radiating means inside said waveguide segment to produce multi-modal and direct heating fields; matching said resonant radiating means to said power source; turning said resonant radiating means to the frequency of said power source; controlling output level of said power source to said resonant radiating means; and matching electromagnetically said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 17
Dependent Claim 240 words
An electromagnetic heating apparatus for heating treatment of localized body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; a below cutoff waveguide structure having one end terminated by an active treatment aperture connected to said power source; a plurality of sets of resonant radiating elements positioned inside said waveguide structure; a first set of resonant radiating elements positioned within said waveguide structure adapted to work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; a second set of resonant radiating elements positioned within said waveguide structure adapted to work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching means matching said sets of resonant radiating elements to said power source: tuning means tuning said sets of resonant radiating elements to the frequency of said power source; control means controlling the output level of said power source to each of said sets of resonant radiating elements; and means to electromagnetically match said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 18
Dependent Claim 240 words
An electromagnetic heating apparatus for heating treatment of localized body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; a below cutoff waveguide structure having one end terminated by an active treatment aperture connected to said power source; a plurality of sets of resonant radiating elements positioned inside said waveguide structure; a first set of resonant radiating elements positioned within said waveguide structure adapted to work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; a second set of resonant radiating elements positioned within said waveguide structure adapted to work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching means matching said sets of resonant radiating elements to said power source: tuning means tuning said sets of resonant radiating elements to the frequency of said power source; control means controlling the output level of said power source to each of said sets of resonant radiating elements; and means to electromagnetically match said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue the composite heating fields resulting from the superposition of said multi-modal and direct heating fields.
Claim 19
Dependent Claim 34 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising coil radiators and lumped capacitive parts working in the low end of said frequency range.
Claim 20
Dependent Claim 35 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising magnetic dipole radiators and lumped capacitive parts working in the low end of said frequency range.
Claim 21
Dependent Claim 35 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising line current radiators and lumped capacitive parts working in the low end of said frequency range.
Claim 22
Dependent Claim 51 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising lumped capacitive parts embodied by a common variable tuning capacitor shared by lumped inductive parts connected in series, parallel or a series-parallel network working in the low end of said frequency range.
Claim 23
Dependent Claim 98 words
An electromagnetic heating apparatus as set forth in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising lumped inductive parts and lumped capacitive parts with flexible current carrying conductors; means for controlling time dependence of said localized heating, said means for controlling time dependence of said localized heating comprising: mechanical control means adjusting the position and configuration of said resonant radiating elements to produce the specific time and spatial profiles of heating fields; and control means for the automatic control of said matching and said tuning of said resonant radiating elements to said power source.
Claim 24
Dependent Claim 51 words
An electromagnetic heating apparatus as claimed in claim 14 including means for controlling said localized heating comprising electronic multi-channel modulating means for individually adjusting the output level of said power source to each of said sets of resonant radiating elements to produce specific time and spatial profiles of said heating fields.
Claim 25
Dependent Claim 88 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant radiators comprising lumped inductive parts and lumped capacitive parts, said lumped inductive parts being electromagnetically coupled together and sharing a common matching circuit to said power source, said matching circuit consisting of a loop terminating a feeding cable from said power source, said loop being magnetically coupled to said inductive parts of said lumped radiators, said matching circuit including a sliding joint means for modifying the extent of said magnetic coupling.
Claim 26
Dependent Claim 65 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are constructed as lumped constant radiating elements working in the low end of a frequency range of said power source and said matching and tuning means couple said lumped constant radiating elements to said power source, said lumped constant radiating elements being positioned inside a shielded box outside said waveguide structure.
Claim 27
Dependent Claim 55 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are constructed as lumped constant radiators working in the low end of said frequency range and said matching and tuning means for coupling said lumped resonant radiating elements to power sources are positioned beyond pure exciting range of said waveguide structure.
Claim 28
Dependent Claim 54 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are lumped constant elements working in the low end of said frequency range and consist of lumped capacitive parts and inductive parts with one electrode of said capacitive parts being grounded to a waveguide wall for limiting stray electromagnetic fields.
Claim 29
Dependent Claim 71 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said resonant radiating elements are constructed as lumped constant elements working in the low end of said frequency range and consist of symmetric lumped inductive parts and symmetric lumped capacitive parts with a mid-point of said symmetric lumped inductive parts or a central electrode of said symmetric lumped capacitive parts being grounded to a waveguide wall for limiting stray electromagnetic fields.
Claim 30
Dependent Claim 22 words
An electromagnetic heating apparatus as claimed in claim 14 wherein two radiating elements of said second set work as mixed exciter/radiating elements.
Claim 31
Dependent Claim 34 words
An electromagnetic heating apparatus as claimed in claim 14 including means for adjusting the relative configuration of said resonant radiating elements with respect to each other and to a wall of said waveguide structure.
Claim 32
Dependent Claim 27 words
An electromagnetic heating apparatus as claimed in claim 14 including means for adjusting the position of said resonant radiating elements with respect to said waveguide active aperture.
Claim 33
Dependent Claim 18 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said waveguide structure has a circular cross-sectional aperture.
Claim 34
Dependent Claim 18 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said waveguide structure has a rectangular cross-sectional aperture.
Claim 35
Dependent Claim 33 words
An electromagnetic heating apparatus as set forth in claim 14 wherein the cross section of said waveguide structure is adjusted to a selected dimensional shape by the addition of cross-sectional transition waveguide segments.
Claim 36
Dependent Claim 23 words
An electromagnetic heating apparatus as claimed in claim 14 wherein mode filters of specific symmetry and configuration are inserted inside said waveguide structure.
Claim 37
Dependent Claim 29 words
An electromagnetic heating apparatus as claimed in claim 14 including means to operate said power source so that the resonant radiating elements can work at a plurality of frequencies.
Claim 38
Dependent Claim 42 words
An electromagnetic heating apparatus as claimed in claim 14 wherein said means for controlling the electromagnetic energy to said radiating elements from said power source comprise multi-channel feeding devices incorporating power level control means and phase shifting means in each feeding channel.
Claim 39
Dependent Claim 29 words
An electromagnetic heating apparatus as claimed in claim 14 including an air gap space between said aperture and said body tissue, said air gap space being of adjustable width.
Claim 40
Dependent Claim 41 words
An electromagnetic heating apparatus as claimed in claim 14 wherein a dielectric bolus of adjustable thickness, dielectric permittivity and magnetic susceptibility covers said waveguide structure aperture, said dielectric bolus being adapted to be interposed between the aperture and said body tissue.
Claim 41
Dependent Claim 57 words
An electromagnetic heating apparatus as claimed in claim 14 for localized heating on a target volume localized inside a quasi-cylindrical body segment wherein said waveguide structure is a radial waveguide of toroidal shape, said active aperture being a circumferential aperture on an inner conductive wall of said radial waveguide and adapted to surround said quasi-cylindrical body segment.
Claim 42
Dependent Claim 53 words
An electromagnetic heating apparatus as claimed in claim 14 including: mechanical means for scanning conformally said hybrid passband applicator over said body surface; and means for programming and executing the pathway, speeds and duty cycle of said scanning while continuously keeping the heating field of said applicator aimed to tissues to be exposed.
Claim 43
Dependent Claim 318 words
An electromagnetic heating apparatus for heating treatment of localized body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; a below cutoff waveguide structure having one end terminated by an active treatment aperture connected to said power source; a plurality of sets of resonant radiating elements positioned inside said waveguide structure comprising; a first set of resonant radiating elements positioned within said waveguide structure adapted to work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; and a second set of resonant radiating elements positioned within said waveguide structure adapted to work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching means matching said sets of resonant radiating elements to said power source; tuning means tuning said sets of resonant radiating elements to the frequency of said power source; control means controlling electromagnetic energy from said power source to each of said sets of resonant radiating elements; means to electromagnetically match said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue, the composite heating fields resulting from this superposition of said multi-modal and direct heating fields; and at least one additional assembly of like element phased array to that of said hybrid passband applicator, said hybrid passband applicator generating a total heating field, said total heating field being preferentially directed over said body tissue, all of said like elements of said phased array being coherent with one another and individually controlled in phase, amplitude and orientation to give rise to a positive interference pattern and to preferential enhanced temperature elevations of said body tissue.
Claim 44
Dependent Claim 318 words
An electromagnetic heating apparatus for heating treatment of localized body tissues to therapeutic temperatures by exposing said tissues to an EM heating field produced by a hybrid passband applicator (HPA) comprising: an electromagnetic power source, the frequency of said source ranging from about 0.1 MHz to 2450 MHz; a below cutoff waveguide structure having one end terminated by an active treatment aperture connected to said power source; a plurality of sets of resonant radiating elements positioned inside said waveguide structure comprising; a first set of resonant radiating elements positioned within said waveguide structure adapted to work as pure exciters producing a multi-modal heating field propagating through said active treatment aperture; and a second set of resonant radiating elements positioned within said waveguide structure adapted to work both as exciters and direct radiators producing a multi-modal heating field and a direct heating field, respectively, both fields propagating through said active treatment aperture; matching means matching said sets of resonant radiating elements to said power source; tuning means tuning said sets of resonant radiating elements to the frequency of said power source; control means controlling electromagnetic energy from said power source to each of said sets of resonant radiating elements; means to electromagnetically match said active treatment aperture to said body tissue for optimizing the energy transfer to the body tissue and directing over said body tissue, the composite heating fields resulting from this superposition of said multi-modal and direct heating fields; and at least one additional assembly of like element phased array to that of said hybrid passband applicator, said hybrid passband applicator generating a total heating field, said total heating field being preferentially directed over said body tissue, all of said like elements of said phased array being coherent with one another and individually controlled in phase, amplitude and orientation to give rise to a positive interference pattern and to preferential enhanced temperature elevations of said body tissue.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

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7.5 Years (Year 8) 2000-02-16 2000-08-17 2001-02-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-02-16 2004-08-17 2005-02-16 $7700.00 Window Closed / Lapsed

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