Patent US484677A successfully refreshed from Google Patents.
Patent US5141748A successfully refreshed from Google Patents.
US5141748A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implant drug delivery device
Assignee: Pfizer Inc
•
Filing: 1989-02-17
•
Granted: 1992-08-25
•
Expires: 2009-02-17
Abstract
Abstract A drug delivery device for subcutaneous implantation in animals having the ability to deliver drug at a controlled rate over a prolonged period of time, comprising a rod shaped polymeric inner matrix with an elongated body and two ends, said matrix having solid particles of the drug to be delivered dispersed throughout the matrix and a polymeric outer membrane wherein the membrane is chemically bound to the surface of the elongated body of the matrix and methods for forming said device.
Inventors
- 👤 Vincent J. Rizzo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:18
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0092; A61K9/0012; A61K9/0019; A61K9/0024
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
117 words
A device for delivering a drug selected from the group consisting of steroids, alkaloids, fatty acids, vitamins, antibodies and birth control agents over a prolonged period of time, said device being adapted to be implanted subcutaneously and comprising an inner rod shaped solid polymer matrix having an elongated body and two ends, said matrix having solid particles of said drug dispersed throughout the matrix, an outer polymer membrane as a coating or laminate chemically bonded to the surface of the elongated body of the matrix, each of said matrix and membrane being a copolymer of methyl vinyl siloxane and dimethylpolysiloxane cross-linked by the same cross-linking agent and with all of said drug being present within the matrix.
Claim 2
Independent Claim
117 words
A device for delivering a drug selected from the group consisting of steroids, alkaloids, fatty acids, vitamins, antibodies and birth control agents over a prolonged period of time, said device being adapted to be implanted subcutaneously and comprising an inner rod shaped solid polymer matrix having an elongated body and two ends, said matrix having solid particles of said drug dispersed throughout the matrix, an outer polymer membrane as a coating or laminate chemically bonded to the surface of the elongated body of the matrix, each of said matrix and membrane being a copolymer of methyl vinyl siloxane and dimethylpolysiloxane cross-linked by the same cross-linking agent and with all of said drug being present within the matrix.
Claim 3
Dependent Claim
17 words
The device of claim 1 wherein said polymer membrane forms an outer coating on said solid matrix.
Claim 4
Dependent Claim
24 words
The device of claim 2 wherein the polymer materials which form the matrix and membrane are cross-linked with a polyalkyl hydrogensiloxane cross-linking agent catalyst.
Claim 5
Dependent Claim
10 words
The device of claim 3 wherein said drug is norgestomet.
Claim 6
Dependent Claim
19 words
The device of claim 1 wherein said polymer membrane is an outer film chemically bonded to the inner matrix.
Claim 7
Dependent Claim
26 words
The device of claim 5 wherein the polymer material which form the matrix and membrane are cross-linked with a polymethylhydrogensiloxane cross-linking agent and a platinum catalyst.
Claim 8
Dependent Claim
10 words
The device of claim 6 wherein said drug is norgestomet.
References Cited (Backward Citations)
US3279996A
Cited
US4351337A
Cited
US4191741A
Cited
EP0013949A2
Cited
US4331651A
Cited
US4666704A
Cited
US4814184A
Cited
GB2207355A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-25 | 1996-02-24 | 1996-08-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-25 | 2000-02-24 | 2000-08-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-25 | 2004-02-24 | 2004-08-25 | $7700.00 | Window Closed / Lapsed |