Patent US5429584A successfully refreshed from Google Patents.
Patent US5002054A successfully refreshed from Google Patents.
US5002054A
Expired / Lapsed
US
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Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the body
Assignee: Ash Access Technology Inc
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Filing: 1989-06-02
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Granted: 1991-03-26
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Expires: 2009-06-02
Abstract
Abstract An implantable filtration and collection device for collecting a filtrate containing a physiological constituent of the body present in an interstitial body space. The device is operable with a negative pressure generating source to withdraw the filtrate from the interstitial body space. The device includes a porous filter made of a material compatible for long-term patency inside the body and adapted to be implanted inside the body in fluid communication with the interstitial space. The pores in the filter are sized not to exceed a predetermined dimension corresponding to the size of the physiological constituent being filtered. A collector in the form of an elongate tube is connected to the filter and and serves to communicate the filtrate externally of the body where it may be withdrawn from the collector by a negative pressure generating source.
Inventors
- 👤 Stephen R. Ash
- 👤 Elsa M. Janle
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:07
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/1468; A61B5/1486; A61B5/14865; A61B5/14525; A61B5/14528; A61B5/14542; A61B5/1473; A61B5/68; A61B5/6846; A61B5/6847; A61B5/686; B; B01; B01D; B01D61/00; B01D61/14; B01D61/18; B01D63/00; B01D63/02; B01D63/024; B01D63/0241; A61B10/00; A61B10/0045; A61B2010/008; B01D2313/00; B01D2313/06
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
168 words
An implantable filtration and collection device for collecting a filtrate containing a physiological constituent of the body present in an interstitial body space, said implantable filtration and collection device being operable with a negative pressure generating source to withdraw the filtrate from the interstitial body space, said implantable filtration and collection device comprising: a filtration means for filtering a filtrate from interstitial fluid in an interstitial space inside the body, said filtration means including a porous filter made of a material compatible for long-term patency inside the body, said filter adapted to be implanted inside the body in fluid communication with the interstitial space and wherein the pores in said filter are sized not to exceed a predetermined dimension corresponding to the size of the physiological constituent being filtered; and a filtrate collector connectable to the negative pressure generating source and including an elongate tube connected to said filter in fluid communication therewith and adapted to extend externally of the body with said filter implanted inside the body.
Claim 2
Dependent Claim
168 words
An implantable filtration and collection device for collecting a filtrate containing a physiological constituent of the body present in an interstitial body space, said implantable filtration and collection device being operable with a negative pressure generating source to withdraw the filtrate from the interstitial body space, said implantable filtration and collection device comprising: a filtration means for filtering a filtrate from interstitial fluid in an interstitial space inside the body, said filtration means including a porous filter made of a material compatible for long-term patency inside the body, said filter adapted to be implanted inside the body in fluid communication with the interstitial space and wherein the pores in said filter are sized not to exceed a predetermined dimension corresponding to the size of the physiological constituent being filtered; and a filtrate collector connectable to the negative pressure generating source and including an elongate tube connected to said filter in fluid communication therewith and adapted to extend externally of the body with said filter implanted inside the body.
Claim 3
Dependent Claim
16 words
The device of claim 1 wherein said filter has a molecular cut off below 100,000 daltons.
Claim 4
Dependent Claim
32 words
The device of claim 1 wherein the physiological constituent of interest include cells present in the interstitial space and said predetermined dimension of the pores in said filter is approximately 100 microns.
Claim 5
Dependent Claim
14 words
The device of claim 3 wherein the physiological constituent of interest is collagen cells.
Claim 6
Dependent Claim
44 words
The device of claim 1 and further comprising: a means for securing the position of said filter inside the body, said securing means including a porous or textured cuff extending around the tube and compatible with adjacent body tissues to promote fibrous tissue ingrowth.
Claim 7
Dependent Claim
87 words
The device of claim 1 wherein said device is adapted for subcutaneous implantation, and wherein said elongate tube includes: (a) a subcutaneous portion adapted to extend within a subcutaneous body space, (b) an external portion adapted to extend externally of the body with the subcutaneous portion extending therein, and (c) an anti-bacteria means for inhibiting the migration of bacteria into the body along said elongate tube, said anti-bacteria means including a silver or silver plated tube segment bridging said subcutaneous and external portions of said elongate tube.
Claim 8
Dependent Claim
32 words
The device of claim 6 wherein the physiological constituent of interest include cells present in the interstitial space and said predetermined dimension of the pores in said filter is approximately 100 microns.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-03-25 | 1994-09-24 | 1995-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-03-25 | 1998-09-24 | 1999-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-03-25 | 2002-09-24 | 2003-03-26 | $7700.00 | Window Closed / Lapsed |