US4633878A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for the automatic insulin or glucose infusion in diabetic subjects, based on the continuous monitoring of the patient's glucose, obtained without blood withdrawal
Assignee: Individual
•
Filing: 1984-04-10
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Granted: 1987-01-06
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Expires: 2004-04-10
Abstract
Abstract A saline solution is pumped through a semi-permeable, hollow-fiber circuit implantable in a living body. A sensor determines the concentration of glucose in the solution. A microcomputer unit controls the supply of insulin and glucose to the body on the basis of the glucose concentration measurements. The hollow fibers form a filter through which only low molecular weight molecules may pass.
Inventors
- 👤 Guiseppe Bombardieri
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:45
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/1468; A61B5/1486; A61B5/14865; A61B5/14525; A61B5/14528; A61B5/68; A61B5/6846; A61B5/6847; A61B5/686; A61M; A61M5/00; A61M5/14; A61M5/168; A61M5/172; A61M5/1723
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
147 words
A device for the determination of the glucose content in the blood of a living body, which comprises a filter implantable in the subcutaneous tissue of said living body and composed of a circuit of biocompatible hollow fibers of polyacrylonitrile or polyethylene having a cut-off of 40,000 which are permeable to glucose but impermeable to the larger molecular weight components of the blood, means for circulating a saline solution through said filter located outside of the body whereby when said filter is implanted in said living body, glucose diffuses from the blood of said living body to said saline solution by dialysis and said saline solution after equilibrium is reached acquires the same concentration of glucose as in the blood of said living body; a sensor located outside of the body and in communication with said filter for determining the concentration of glucose connected to said filter.
Claim 2
Independent Claim
147 words
A device for the determination of the glucose content in the blood of a living body, which comprises a filter implantable in the subcutaneous tissue of said living body and composed of a circuit of biocompatible hollow fibers of polyacrylonitrile or polyethylene having a cut-off of 40,000 which are permeable to glucose but impermeable to the larger molecular weight components of the blood, means for circulating a saline solution through said filter located outside of the body whereby when said filter is implanted in said living body, glucose diffuses from the blood of said living body to said saline solution by dialysis and said saline solution after equilibrium is reached acquires the same concentration of glucose as in the blood of said living body; a sensor located outside of the body and in communication with said filter for determining the concentration of glucose connected to said filter.
Claim 3
Dependent Claim
12 words
The device according to claim 1 wherein said circuit is spiral shaped.
Claim 4
Dependent Claim
19 words
The device according to claim 1 wherein said filter is implantable in the abdominal wall of said living body.
Claim 5
Dependent Claim
64 words
The device as claimed in claim 1 further comprising control means connected to said sensor and linked to said living body for selectively introducing insulin or glucose to said living body to counteract glucose present in said solution in said filter in amounts above a determined range and to counteract an insufficiency of glucose in said filter in amounts below said determined range, respectively.
Claim 6
Dependent Claim
113 words
The device according to claim 4 wherein said control means comprises a source of insulin, an insulin pump connected to said source of insulin and linked to said living body, a source of glucose, a glucose pump connected to said source of glucose and linked to said living body and microprocessor means coupling said sensor to said insulin pump and to said glucose pump for operating said insulin pump to supply insulin to said living body when said sensor determines a glucose concentration greater than a determined level and for operating said glucose pump to supply glucose to said living body when said sensor determines a glucose concentration less than a determined level.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-01-05 | 1990-07-07 | 1991-01-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-01-05 | 1994-07-07 | 1995-01-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-01-05 | 1998-07-07 | 1999-01-06 | $7700.00 | Window Closed / Lapsed |