Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth

Claim 1

A method for locating on the cornea an optical lens having a preselected geometric shape and power, said optical lens comprising an optical portion having an outer edge, a posterior surface and an anterior surface, said optical lens being formed of a hydrogel polymer formed by the free radical polymerization of a hydrophilic monomer solution gelled and crosslinked to form a three dimensional polymeric meshwork for anchoring collagen; and a stock solution of collagen added to and interdisposed within said polymeric meshwork forming a collagen-hydrogel for promoting epithelial cell growth comprising the steps of: removing from Bowman's membrane over the pupillary zone of the eye a portion of corneal epithelium on an area slightly greater than the generalized shape of said optical lens; forming on Bowman's membrane a "v" shaped annular groove having a diameter substantially equal to the maximum geometrical dimensions of said optical lens and defining therearound a peripheral edge and medial edge and having a preselected depth which is less than the thickness of the corneal stroma; dissecting the peripheral edge of said groove forming a wing of corneal tissue having a preselected length; placing the posterior surface of said optical lens on the anterior surface of Bowman's membrane and positioning the outer edge of said optical lens under said corneal wing, whereby the corneal wing lies flush with and in contact with the anterior surface of said lens; and affixing the optical lens to the Bowman's membrane over the pupillary zone of the eye to maintain the same on the cornea with the posterior surface in contact with Bowman's membrane and the corneal wing overlying the edge of said optical lens enabling corneal epithelium to touch and interact with said optical lens formed of a stock solution of collagen added to a hydrogel polymer for promoting epithelial cell growth and adherence to said optical lens and to respond to the epithelial cells growth promoting constituent in said optical lens formed of a stock solution of collagen added to a hydrogel polymer over a healing period wherein epithelial cells grow in from the edge of said optical lens and over the same enabling the epithelial cells to adhere to and implant said optical lens in the cornea under a new growth of corneal epithelium formed from several layers of epithelial cells adhering to the optical lens.

Claim 2

A method for locating on the cornea an optical lens having a preselected geometric shape and power, said optical lens comprising an optical portion having an outer edge, a posterior surface and an anterior surface, said optical lens being formed of a hydrogel polymer formed by the free radical polymerization of a hydrophilic monomer solution gelled and crosslinked to form a three dimensional polymeric meshwork for anchoring collagen; and a stock solution of collagen added to and interdisposed within said polymeric meshwork forming a collagen-hydrogel for promoting epithelial cell growth comprising the steps of: removing from Bowman's membrane over the pupillary zone of the eye a portion of corneal epithelium on an area slightly greater than the generalized shape of said optical lens; forming on Bowman's membrane a "v" shaped annular groove having a diameter substantially equal to the maximum geometrical dimensions of said optical lens and defining therearound a peripheral edge and medial edge and having a preselected depth which is less than the thickness of the corneal stroma; dissecting the peripheral edge of said groove forming a wing of corneal tissue having a preselected length; placing the posterior surface of said optical lens on the anterior surface of Bowman's membrane and positioning the outer edge of said optical lens under said corneal wing, whereby the corneal wing lies flush with and in contact with the anterior surface of said lens; and affixing the optical lens to the Bowman's membrane over the pupillary zone of the eye to maintain the same on the cornea with the posterior surface in contact with Bowman's membrane and the corneal wing overlying the edge of said optical lens enabling corneal epithelium to touch and interact with said optical lens formed of a stock solution of collagen added to a hydrogel polymer for promoting epithelial cell growth and adherence to said optical lens and to respond to the epithelial cells growth promoting constituent in said optical lens formed of a stock solution of collagen added to a hydrogel polymer over a healing period wherein epithelial cells grow in from the edge of said optical lens and over the same enabling the epithelial cells to adhere to and implant said optical lens in the cornea under a new growth of corneal epithelium formed from several layers of epithelial cells adhering to the optical lens.