US4581030A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Collagen replacement prothesis for the cornea
Assignee: General Hospital Corp
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Filing: 1984-12-18
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Granted: 1986-04-08
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Expires: 2004-12-18
Abstract
Abstract This invention relates to a prosthetic replacement for the cornea and particularly to a transparent collagen material useful for making such a prosthesis and to methods for making such transparent collagen material. The prosthesis is preferably composed of a native, non-fibrilized, transparent collagen material formed from a soluble collagen solution by ultracentrifuging to form a pellet and fixing the same pellet, whereby the collagen material has less than 5% absorbance of light at 900 nm for a 5 mm thick sample and comprises polyhydroxyethylmethacrylate or vitrosin, in a range of from 0.01 to 50.0 percent by weight, based on the collagen protein.
Inventors
- 👤 Romaine R. Bruns
- 👤 Jerome Gross
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:59
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/142; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/24; C; C09; C09H; C09H7/00; A61F2250/00; A61F2250/0058; A61F2250/0091; A61F2310/00; A61F2310/00005; A61F2310/00365; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
38 words
A prosthetic cornea replacement comprising collagen wherein the collagen component consists essentially of a native, non-fibrillized, transparent, crosslinked collagen material that has less than 5% absorbance of light at 900 mm for a 5 nm thick cross section.
Claim 2
Dependent Claim
38 words
A prosthetic cornea replacement comprising collagen wherein the collagen component consists essentially of a native, non-fibrillized, transparent, crosslinked collagen material that has less than 5% absorbance of light at 900 mm for a 5 nm thick cross section.
Claim 3
Dependent Claim
16 words
The cornea replacement of claim 1, wherein such replacement contains between 0.5 and 20% collagen protein.
Claim 4
Dependent Claim
21 words
The cornea replacement of claim 1, further comprising polyhydroxyethylmethacrylate or vitrosin, in a range of between 0.01 to 50% by weight.
Claim 5
Dependent Claim
62 words
A native, non-fibrilized, transparent collagen material formed from a soluble collagen solution by ultracentrifuging to form a pellet and fixing said pellet, said collagen material having less than 5% absorbance of light at 900 nm for a 5 mm thick sample and comprising polyhydroxyethylmethacrylate or vitrosin, in a range of from 0.01 to 50 percent by weight, based on the collagen protein.
Claim 6
Dependent Claim
62 words
A native, non-fibrilized, transparent collagen material formed from a soluble collagen solution by ultracentrifuging to form a pellet and fixing said pellet, said collagen material having less than 5% absorbance of light at 900 nm for a 5 mm thick sample and comprising polyhydroxyethylmethacrylate or vitrosin, in a range of from 0.01 to 50 percent by weight, based on the collagen protein.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-04-07 | 1989-10-07 | 1990-04-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-04-07 | 1993-10-07 | 1994-04-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-04-07 | 1997-10-07 | 1998-04-08 | $7700.00 | Window Closed / Lapsed |