Patent US4994013A successfully refreshed from Google Patents.
US4994013A
Expired / Lapsed
US
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Pellet for a radioactive seed
Assignee: Cordis Corp
•
Filing: 1988-07-28
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Granted: 1991-02-19
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Expires: 2008-07-28
Abstract
Abstract A pellet for a radioactive seed, suitable for use in certain medical radiological treatments, comprising a metallic X-ray detectable marker rod such as tungsten coated with a radioactive-absorbing material such as carbon in a binder wherein a radioactive material is absorbed. Such pellets are encapsulated in a material such as titanium to form an effectively sealed radioactive seed which is useful in certain medical radiological treatments.
Inventors
- 👤 Krishnan Suthanthiran
- 👤 Raj Lakshman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:14
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1027; A61K; A61K51/00; A61K51/12; A61K51/1282; G; G21; G21G; G21G4/00; G21G4/04; G21G4/06; G21G4/08; A61N2005/1019; A61N2005/1024
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
46 words
A pellet for a radioactive seed for use in radiation therapy, comprising a metallic rod substrate uniformly and completely coated with binder material having radioactive-absorbing material in the binder material wherein the radioactive-absorbing material is selected from the group consisting of carbon, activated carbon and charcoal.
Claim 2
Dependent Claim
46 words
A pellet for a radioactive seed for use in radiation therapy, comprising a metallic rod substrate uniformly and completely coated with binder material having radioactive-absorbing material in the binder material wherein the radioactive-absorbing material is selected from the group consisting of carbon, activated carbon and charcoal.
Claim 3
Dependent Claim
11 words
The pellet of claim 1, wherein said binder material is water-insoluble.
Claim 4
Dependent Claim
13 words
The pellet of claim 1, wherein said binder material is a cellulose ester.
Claim 5
Dependent Claim
11 words
The pellet of claim 1, wherein said binder comprises cellulose acetate.
Claim 6
Dependent Claim
14 words
The pellet of claim 1, wherein said binder material is insoluable in organic solvents.
Claim 7
Dependent Claim
25 words
The pellet of claim 1, wherein said coating of binder material has a thickness in the range of about 0.05 mm to about 1.0 mm.
Claim 8
Dependent Claim
26 words
The pellet of claim 1, wherein the metallic rod substrate comprises a material selected from the group consisting of tungsten, stainless steel, tin, or alloys thereof.
Claim 9
Dependent Claim
16 words
The pellet of claim 1, wherein a metallic rod substrate comprises tungsten or an alloy thereof.
Claim 10
Dependent Claim
37 words
The pellet of claim 1, wherein the metallic rod substrate has a length in the range of about 1 mm to about 10 mm and a diameter in the range of about 0.1 mm to about 1.0.
Claim 11
Dependent Claim
14 words
The pellet of claim 1, wherein the metallic rod substrate has a circular cross-section.
Claim 12
Dependent Claim
60 words
The pellet of claim 1, wherein the radioactive-absorbing material is selected from the group consisting of carbon, activated carbon, charcoal, ion exchange resins such as sulfonated polystyrene resins, methylene-sulfonic phenolic resins, phosphoric polystyrene resins, polystyrene resins containing quaternary ammonium groups, pyridinium polystyrene resins, epoxy-polyamine resins containing tertiary and quaternary ammonium groups, iminodiacetic polystyrene resins, and polystyrene resins containing polyamine groups.
Claim 13
Dependent Claim
27 words
The pellet of claim 1, wherein the radioactive-absorbing material is particulate and of a particle size in the range of about 1.0 micron to about 100.0 microns.
Claim 14
Dependent Claim
18 words
The pellet of claim 1, wherein the radioactive absorbing material is particulate and dispersed throughout the binder material.
Claim 15
Dependent Claim
30 words
The pellet of claim 1, wherein the radioactive absorbing material is particulate and is located primarily in a discrete layer at or near the outer surface of the binder layer.
Claim 16
Dependent Claim
30 words
The pellet of claim 1, wherein the radioactive-absorbing material comprises an amount in the range of about 10% to about 50% by weight of the total binder/radio- active-absorbing material layer.
Claim 17
Dependent Claim
28 words
The pellet of claim 15, wherein the binder comprises about 30% by weight and the radioactive-absorbing material comprises about 70% by weight of the total binder/radioactive-absorbing material layer.
Claim 18
Dependent Claim
65 words
The pellet of claim 1, having radioactive material absorbed in the radioactive absorbing material, wherein the radioactive material is selected from the group consisting of I-125, Pd-103, Cs-131, Cs-134, Cs-137, Ag-111, U-235, Au-198, P-32 and C-14, as well as isotopes of rubidium, calcium, barium, scandium, titanium, chromium, manganese, iron, cobalt, nickel, copper, zinc, yttrium, zirconium, indium, cadmium, the rare earths, mercury, lead, americium and neptunium.
Claim 19
Dependent Claim
21 words
The pellet of claim 1, having radioactive material absorbed in the radioactive absorbing material, wherein the radioactive material therein is I-125.
Claim 20
Dependent Claim
40 words
The pellet of claim 1 having radioactive material absorbed in the radioactive absorbing material, additionally comprising an external capsule covering the exterior of the binder/radioactive-absorbing material layer and substantially sealing the pellet within the capsule, thereby forming a radioactive seed.
Claim 21
Dependent Claim
37 words
The radioactive seed of claim 19, wherein said capsule comprises a material selected from the group consisting of titanium, stainless steel, platinum, gold, nickel alloys, nylon, silicon, rubber, polyester resin, chlorinated hydrocarbon resins, aluminum, and aluminum alloys.
Claim 22
Dependent Claim
11 words
The radioactive seed of claim 19, wherein the capsule comprises titanium.
Claim 23
Dependent Claim
23 words
The radioactive seed of claim 19, wherein the capsule wall thickness is in the range of about 0.05 mm to about 1.0 mm.
Claim 24
Dependent Claim
36 words
The radioactive seed of claim 19, wherein the capsule is of a size in the range of about 1.5 mm to about 15 mm in length, and about 0.3 mm to about 4.0 mm in diameter.
Claim 25
Dependent Claim
24 words
The radioactive seed of claim 19, wherein the amount of radioactivity present therein is in the range of about 0.1 to about 1000 mCi.
Claim 26
Dependent Claim
23 words
The radioactive seed of claim 19, wherein the amount of radioactivity therein is in the range of about 0.3 to about 100 mCi.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-02-18 | 1994-08-20 | 1995-02-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-02-18 | 1998-08-20 | 1999-02-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-02-18 | 2002-08-20 | 2003-02-19 | $7700.00 | Window Closed / Lapsed |