US4902287A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sterilizable system for blood storage
Assignee: Bayer Corp
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Filing: 1987-09-24
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Granted: 1990-02-20
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Expires: 2007-09-24
Abstract
Abstract An improved heat sterilizable blood bag system adapted for containing and mixing of different materials originally placed in separate but potentially communicating compartments. The improvement comprises of having a smaller squeezable compartment for one material attached to and capable of communicating with a larger compartment for the other material. The material in the smaller compartment is separated from the interior of the larger compartment by means of an externally manipulatable closure means which, when opened, permits mixture of the contents in the first compartment and contents of the second compartment when the smaller compartment is repeatedly squeezed.
Inventors
- 👤 Raleigh A. Carmen
- 👤 Chi-Yong Chong
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:07
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/02; A61L2/04; A61L2/06; A61L2/07; A61J; A61J1/00; A61J1/05; A61J1/06; A61J1/067; A61J1/10; A61J1/14; A61J1/20; A61J1/2089; A61J1/2003; A61J1/202; A61J1/2027; A61J1/2037
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
125 words
In a closed, heat sterilizable, blood bag system comprising at least one flexible bag adapted to receive and store a blood component, the improvement comprising a squeezable, resilient compartment extending from the bag vis a conduit and containing a solid, pH buffering material within the compartment, the solid material being separated from the interior of the flexible bag by means of an externally manipulable closure system located outside of the conduit which, when opened, permits the mixture of the solid pH buffering material with the contents of the bag, thereby assuring pH control of the bag contents over prolonged periods of time, the squeezable, resilient compartment providing means for drawing the contents of the flexible bag into the compartment when the closure system is opened.
Claim 2
Dependent Claim
125 words
In a closed, heat sterilizable, blood bag system comprising at least one flexible bag adapted to receive and store a blood component, the improvement comprising a squeezable, resilient compartment extending from the bag vis a conduit and containing a solid, pH buffering material within the compartment, the solid material being separated from the interior of the flexible bag by means of an externally manipulable closure system located outside of the conduit which, when opened, permits the mixture of the solid pH buffering material with the contents of the bag, thereby assuring pH control of the bag contents over prolonged periods of time, the squeezable, resilient compartment providing means for drawing the contents of the flexible bag into the compartment when the closure system is opened.
Claim 3
Dependent Claim
14 words
The system of claim 1 wherein the solid pH control material comprises sodium bicarbonate.
Claim 4
Dependent Claim
18 words
The system of claim 2 wherein the sodium bicarbonate is in the form of a powder or tablet.
Claim 5
Dependent Claim
12 words
The system of claim 1 wherein the closure system comprises frangible valve.
Claim 6
Dependent Claim
101 words
In a method of storing platelets comprising holding platelets in a closed, flexible, gas permeable plastic bag for a given period, the improvement which comprises having attached to the bag a separate squeezable compartment which includes a heat sterilizable, solid pH buffering material, the buffering material being separated from the interior by means of an externally manipulatable closure system, the closure system capable of being manipulated to open communication between the interior of the bag and the interior of the compartment such that the contents of the bag and the compartment can be mixed for pH control of the bag contents.
Claim 7
Dependent Claim
101 words
In a method of storing platelets comprising holding platelets in a closed, flexible, gas permeable plastic bag for a given period, the improvement which comprises having attached to the bag a separate squeezable compartment which includes a heat sterilizable, solid pH buffering material, the buffering material being separated from the interior by means of an externally manipulatable closure system, the closure system capable of being manipulated to open communication between the interior of the bag and the interior of the compartment such that the contents of the bag and the compartment can be mixed for pH control of the bag contents.
Claim 8
Dependent Claim
42 words
The method of claim 5 wherein the pH buffering material comprises a bicarbonate salt, the amount of which is capable of maintaining the pH of a unit of platelets within the range of 6.8 to 7.4 for at least about 10 days.
Claim 9
Dependent Claim
22 words
The method of claim 6 wherein the buffering material is sodium bicarbonate in the form of a powder or a compressed tablet.
Claim 10
Dependent Claim
37 words
The method of claim 5 wherein the bag is made from a plastic film having a film thickness, plasticizer type and plasticizer content which, together, assure a gas transmissibility which facilitates long term storage of the platelets.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-02-19 | 1993-08-21 | 1994-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-02-19 | 1997-08-21 | 1998-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-02-19 | 2001-08-21 | 2002-02-20 | $7700.00 | Window Closed / Lapsed |