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US4863974A Expired / Lapsed US ⏱️ 0.0 years remaining

Bone growth matrix and process for making it

Assignee: W.L. Gore and Associates Inc
•
Filing: 1988-08-03
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Granted: 1989-09-05
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Expires: 2008-08-03
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Abstract

Abstract The present invention provides for a bone growth material for filling in defects or hollow portions of bones to be ingrown by and coalesce with bone tissues wherein the bone growth material is comprised of expanded PTFE and calcium phosphate.

Inventors

  • 👤 Robert S. Mallouk
  • 👤 William P. Mortimer, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:51
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61L27/40; A61L27/44; A61L27/46; Y; Y10; Y10S; Y10S521/00; Y10S521/919; Y10S623/00; Y10S623/924; Y10S623/925

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 94 words
A bone growth material for filling in defects or hollow portions of bones to coalesce with bone tissue wherein said bone growth matrix consists essentially of between 1.5 to 12% by volume expanded polytetrafluoroethylene having a void content of greater than 70% and comprising a matrix of interconnected channels defined by nodes and fibrils and between 2.5 to 18% by volume calcium phosphate particles interspersed throughout the expanded polytetrafluoroethylene, in which the matrix is coherent and resilient and in which the interconnected channels are of a size capable of allowing for vascularized tissue ingrowth.
Claim 2
Dependent Claim 94 words
A bone growth material for filling in defects or hollow portions of bones to coalesce with bone tissue wherein said bone growth matrix consists essentially of between 1.5 to 12% by volume expanded polytetrafluoroethylene having a void content of greater than 70% and comprising a matrix of interconnected channels defined by nodes and fibrils and between 2.5 to 18% by volume calcium phosphate particles interspersed throughout the expanded polytetrafluoroethylene, in which the matrix is coherent and resilient and in which the interconnected channels are of a size capable of allowing for vascularized tissue ingrowth.
Claim 3
Dependent Claim 26 words
A bone growth material as described in claim 1 wherein said calcium phosphate is calcium triphosphate of the formula CA 5 (PO 4 ) 3 OH.
Claim 4
Dependent Claim 17 words
A bone growth material as described in claim 1 wherein said calcium phosphate is resorbable calcium phosphate.
Claim 5
Dependent Claim 35 words
A bone growth material as described in claim 1 wherein said expanded PTFE comprises between 3 and 6 by volume percent of the matrix and said calcium phosphate comprises between 4 and 8 volume percent.

References Cited (Backward Citations)

US3443261A Cited
US4256845A Cited
US4373217A Cited
US4548959A Cited
US4497075A Cited
US4576608A Cited
US4518430A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-09-04 1993-03-06 1993-09-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-09-04 1997-03-06 1997-09-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-09-04 2001-03-06 2001-09-05 $7700.00 Window Closed / Lapsed

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