Hydroxyapatite, ceramic material and process for preparing thereof

Claim 2

A ceramic material consisting essentially of hydroxyapatite ceramic having a ratio of calcium atoms to phosphorus atoms of 1.67 to 1.69, an average crystal size of 4 to 20μ, a density of 3.14 to 3.16 g/cm 3 and a thermal stability wherein whitlockite is not shown after said hydroxyapatite ceramic is heated for one hour at a temperature of 1350° C., said ceramic being colourless or semi transparent.

Claim 3

The ceramic material according to claim 1, wherein the hydroxyapatite ceramic is prepared by sintering a dried, filtered cake of hydroxyapatite having a structure possessing the three-dimensional order with an average opening radius of 50 to 150 Å and a pore cavity of 0.2 to 0.8 cm 3 /g, said cake comprising hydroxyapatite having an atomic ratio of calcium to phosphorus of 1.67 to 1.69 and a dimension including a length of 150 to 1200 Å, a width of 50 to 400 Å, and a ratio of said length to said width of 3 to 10.

Claim 4

An implant material consisting essentially of (1) a ceramic material consisting essentially of hydroxyapatite ceramic having a ratio of calcium atoms to phosphorous atoms of 1.67 to 1.69, an average crystal size of 4 to 20μ, a density of 3.14 to 3.16 g/cm 3 and a thermal stability wherein whitlockite is not shown after said hydroxyapatite is heated for one hour at a temperature of 1350° C., said ceramic being colourless or semi transparent and (2) a bonding material having a biological acceptability to a living body, wherein the ratio of a surface area of the hydroxyapatite phase of the ceramic material of the implant material to that of the bonding material in the surface thereof that can be adhered to bone is 5:95 to 70:30.

Claim 5

An implant material consisting essentially of (1) a ceramic material consisting essentially of hydroxyapatite ceramic having a ratio of calcium atoms to phosphorous atoms of 1.67 to 1.69, an average crystal size of 4 to 20μ, a density of 3.14 to 3.16 g/cm 3 and a thermal stability wherein whitlockite is not shown after said hydroxyapatite is heated for one hour at a temperature of 1350° C., said ceramic being colourless or semi transparent and (2) a bonding material having a biological acceptability to a living body, wherein the ratio of a surface area of the hydroxyapatite phase of the ceramic material of the implant material to that of the bonding material in the surface thereof that can be adhered to bone is 5:95 to 70:30.

Claim 6

The implant material according to claim 3, wherein both the ceramic material and the bonding material make up the surface part contacting with bone of the implant material.

Claim 7

The implant material according to claim 3, wherein the bonding material is one homopolymer or a mixture of more than one homopolymer selected from the group consisting of polycondensate of bisphenol A and glycidyl methacrylate, poly(methyl methacrylate), poly(2-hydroxyethyl methacrylate), poly(triethyleneglycol dimethacrylate), polyethylene, polysulfone resin, polyamide resin, polyester resin, poly(tetrafluoroethylene), poly(vinylidene fluoride) and polycarbonate resin, or a copolymer comprising more than one monomer constituting said homopolymers.