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US4802475A Expired / Lapsed US ⏱️ 0.0 years remaining

Methods and apparatus of applying intra-lesional cryotherapy

Assignee: Individual
•
Filing: 1987-06-22
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Granted: 1989-02-07
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Expires: 2007-06-22
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Abstract

Abstract There is described a method of performing intra-lesional cryosurgery utilizing a specifically shaped tubular needle having a front piercing surface coextensive with an opening. The needle is introduced into the skin from one point and runs through deeper tissues based on the surface orientation of the needle. The piercing surface of the needle is directed through a second point where it emerges from the skin. The needle as indicated is a hollow tubular member and has one end which is adapted to receive a source of a cryrogen gas. The gas is passed through the needle and produces a lowering of the needle temperature. This low temperature is directed to the surrounding tissues to form an ice cylinder about the imbedded part of the needle in the deeper tissues. This ice cylinder affords to selectively freeze the tissue and thereby destroys the lesion being treated. A plurality of different shaped needles are shown to accommodate different types and different depth lesions. Some needles are also selectively insulated at various portions to cause the uninsulated portion of the needle to selectively apply freezing temperatures to tissues in selective directions.

Inventors

  • 👤 Ahmed H. A. G. Weshahy

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:54
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/02; A61B18/0218; Y; Y10; Y10S; Y10S128/00; Y10S128/27

Claims Analysis

Total Claims: 24
Claim 1
Independent Claim 109 words
A method of applying intra-lesional cryotherapy, comprising the steps of: inserting a hollow thermally conductive needle having a front opening through the skin of a patient with said needle having a given surface portion adapted to position the same at a given depth according to the location of a lesion to cause said front opening of the needle to protrude from the patient's skin when said given portion is in position and applying a cryogen through the internal hollow of said needle to cause said given portion to freeze tissue in the area of said lesion while said cryogen is being discharged from said front opening of said needle.
Claim 2
Independent Claim 109 words
A method of applying intra-lesional cryotherapy, comprising the steps of: inserting a hollow thermally conductive needle having a front opening through the skin of a patient with said needle having a given surface portion adapted to position the same at a given depth according to the location of a lesion to cause said front opening of the needle to protrude from the patient's skin when said given portion is in position and applying a cryogen through the internal hollow of said needle to cause said given portion to freeze tissue in the area of said lesion while said cryogen is being discharged from said front opening of said needle.
Claim 3
Dependent Claim 20 words
The method according to claim 1, wherein said given portion of said needle includes a bend at a predetermined angle.
Claim 4
Dependent Claim 35 words
The method according to claim 1, further including the step of placing an insulating material about the skin of the patient after inserting said needle to protect the skin during the application of said cryogen.
Claim 5
Dependent Claim 23 words
The method according to claim 1, wherein said front opening of said needle is contiguous with a sharp tip for penetrating the skin.
Claim 6
Dependent Claim 47 words
The method according to claim 1, wherein the step of inserting includes inserting a needle having a hook-like front portion into the skin of a patient with the hook portion constituting said given portion and having a front which protrudes from the skin for discharging said cryogen.
Claim 7
Dependent Claim 32 words
The method according to claim 1, including the further step of selectively insulating portions of said needle prior to insertion of the same to form said given portion of a predetermined configuration.
Claim 8
Dependent Claim 22 words
The method according to claim 1, wherein said needle has a diameter between 0.5-1.0 mm and a length greater than 3 cm.
Claim 9
Dependent Claim 16 words
The method according to claim 7, wherein the length of said needle is between 8-16 cm.
Claim 10
Dependent Claim 17 words
The method according to claim 1, wherein said cyrogen is selected from nitrous oxide and liquid nitrogen.
Claim 11
Dependent Claim 28 words
The method according to claim 6, wherein the step of selectively insulating portions of said needle prior to insertion of the same includes insulating said portions with Teflon.
Claim 12
Dependent Claim 25 words
The method according to claim 1, further including the step of pulling said needle upwardly while applying said cryogen to raise said skin during application.
Claim 13
Independent Claim 136 words
A method of performing cryosurgery on a lesion associated with the skin of a patient, comprising the steps of: inserting a relatively long hollow thermally conducting tubular needle through the skin of a patient in the area of said lesion, said needle having a sharpened apex surrounded by a front opening at a first end and having an opening at a second end with said needle having a given shaped portion that is positioned in the area of said lesion when said needle is inserted such that said front opening protrudes from the patient's skin, applying a source of cryogen to said opening at said second end to cause said cryogen to pass through the hollow of said needle and to be discharged through said front opening to freeze tissue in the vicinity of said lesion.
Claim 14
Independent Claim 136 words
A method of performing cryosurgery on a lesion associated with the skin of a patient, comprising the steps of: inserting a relatively long hollow thermally conducting tubular needle through the skin of a patient in the area of said lesion, said needle having a sharpened apex surrounded by a front opening at a first end and having an opening at a second end with said needle having a given shaped portion that is positioned in the area of said lesion when said needle is inserted such that said front opening protrudes from the patient's skin, applying a source of cryogen to said opening at said second end to cause said cryogen to pass through the hollow of said needle and to be discharged through said front opening to freeze tissue in the vicinity of said lesion.
Claim 15
Dependent Claim 24 words
The method according to claim 12, wherein the step of inserting includes inserting a hollow stainless steel needle having a bent given shaped portion.
Claim 16
Dependent Claim 24 words
The method according to claim 12, wherein the step of inserting includes inserting a hollow stainless steel needle having an arcuate given shaped portion.
Claim 17
Dependent Claim 33 words
The method according to claim 12, further including the step of selectively insulating portions of said needle prior to insertion to provide a selected surface area for conduction to selectively freeze said tissue.
Claim 18
Dependent Claim 33 words
The method according to claim 12, further including the step of placing an insulating material about the skin of said patient after inserting said needle to protect the skin while applying said cryogen.
Claim 19
Dependent Claim 33 words
The method according to claim 12, further including the step of pulling said needle during the application of said cryogen to raise the skin of the patient in said area of said lesion.
Claim 20
Dependent Claim 20 words
The method according to claim 12, wherein said front opening is canted to discharge said cryogen in a given direction.
Claim 21
Dependent Claim 158 words
A probe to be employed in a cryosurgical operation comprising: a hollow thermal conducting tubular needle having a front opening at a first end and back opening at a second end, said tubular needle having a given surface portion between said ends of a shape to allow said needle to be inserted into the skin of a patient at a given depth according to the location of a lesion to be removed by freezing the tissue in the area of said lesion with said given surface portion always allowing said front opening at said first end to protrude from the skin of a patient when said needle is inserted to allow cryogen to escape into the atmosphere, means coupled to said second end and adapted to receive a source of a cryogen, including an insulator material surrounding surface portions of said needle which insulated surface portions define a given thermal conducting non-insulated region for selectively freezing said lesion.
Claim 22
Dependent Claim 158 words
A probe to be employed in a cryosurgical operation comprising: a hollow thermal conducting tubular needle having a front opening at a first end and back opening at a second end, said tubular needle having a given surface portion between said ends of a shape to allow said needle to be inserted into the skin of a patient at a given depth according to the location of a lesion to be removed by freezing the tissue in the area of said lesion with said given surface portion always allowing said front opening at said first end to protrude from the skin of a patient when said needle is inserted to allow cryogen to escape into the atmosphere, means coupled to said second end and adapted to receive a source of a cryogen, including an insulator material surrounding surface portions of said needle which insulated surface portions define a given thermal conducting non-insulated region for selectively freezing said lesion.
Claim 23
Dependent Claim 27 words
The probe according to claim 19, wherein said given surface portion is manifested by an angular bend in said tubular needle between said first and second ends.
Claim 24
Dependent Claim 26 words
The probe according to claim 19, wherein said surface portion is manifested by an arcuate curve in said tubular needle between said first and second ends.

References Cited (Backward Citations)

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US3434477A Cited
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US4275734A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-02-07 1992-08-08 1993-02-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-02-07 1996-08-08 1997-02-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-02-07 2000-08-08 2001-02-07 $7700.00 Window Closed / Lapsed

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