Patent US4548208A successfully refreshed from Google Patents.
Patent US4777962A successfully refreshed from Google Patents.
US4777962A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for distinguishing central obstructive and mixed apneas by external monitoring devices which measure rib cage and abdominal compartmental excursions during respiration
Assignee: VivoMetrics Inc
•
Filing: 1987-02-17
•
Granted: 1988-10-18
•
Expires: 2007-02-17
Abstract
Abstract An apparatus and method for distinguishing between different types of apneic episodes. The method includes measuring a new index, TCD/VT, and measuring the phase relation between the abdominal and rib cage contributions to total respiration volume. The episode is classified as central, obstructive or mixed based on the value of TCD/VT and the phase relation.
Inventors
- 👤 Herman Watson
- 👤 Marvin A. Sackner
- 👤 Anne S. Belsito
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:16
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/72; A61B5/7235; A61B5/7264; A61B5/103; A61B5/11; A61B5/113; A61B5/1135; G; G16; G16H; G16H50/00; G16H50/20
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
160 words
A method for differentiating among central, obstructive and mixed apneas in a subject comprising (a) determining the existence of an apneic event; (b) measuring TCD during said apneic event and providing a signal indicative thereof; (c) measuring SUM (VT) during said apneic event and providing a signal indicative thereof; (d) displaying said TCD and SUM (VT) signals on a compressed plot; (e) classifying said event as a central apneic event when said displayed TCD and SUM (VT) signals are coincident or parallel; (f) classifying said event as an obstructive apneic event when said displayed TCD signal slopes at an angle from said displayed SUM (VT) signal during substantially said entire apneic event; and (g) classifying said event as a mixed apneic event when said displayed SUM (VT) and TCD signals are coincident or parallel for a portion of said apneic event and said displayed TCD signal slopes away from said SUM (VT) signal during another portion of said apneic event.
Claim 2
Independent Claim
160 words
A method for differentiating among central, obstructive and mixed apneas in a subject comprising (a) determining the existence of an apneic event; (b) measuring TCD during said apneic event and providing a signal indicative thereof; (c) measuring SUM (VT) during said apneic event and providing a signal indicative thereof; (d) displaying said TCD and SUM (VT) signals on a compressed plot; (e) classifying said event as a central apneic event when said displayed TCD and SUM (VT) signals are coincident or parallel; (f) classifying said event as an obstructive apneic event when said displayed TCD signal slopes at an angle from said displayed SUM (VT) signal during substantially said entire apneic event; and (g) classifying said event as a mixed apneic event when said displayed SUM (VT) and TCD signals are coincident or parallel for a portion of said apneic event and said displayed TCD signal slopes away from said SUM (VT) signal during another portion of said apneic event.
Claim 3
Dependent Claim
68 words
The method according to claim 1, further comprising measuring PR during said apneic event and confirming the classification of said apneic event as a central apneic event if PR is about 98 to about 99, confirming said apneic event as an obstructive apneic event if PR is less than about 97, and confirming said apneic event as a mixed apneic event if PR is less than about 97.
Claim 4
Dependent Claim
75 words
The method according to claim 1, further comprising measuring intrapleural pressure during said apneic event and confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and confirming classification of said event or a component thereof as an obstructive apnea if a change in intrapleural pressure is recorded during said event or said component thereof, respectively.
Claim 5
Dependent Claim
75 words
The method according to claim 2, further comprising measuring intrapleural pressure during said apneic event and confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and confirming classification of said event or a component thereof as an obstructive apnea if a change in intrapleural pressure is recorded during said event or said component thereof, respectively.
Claim 6
Independent Claim
127 words
A method for differentiating among central, obstructive and mixed apneas in a subject comprising (a) determining the existence of an apneic event; (b) measuring TCD/VT during said apneic event; (c) measuring PR during said apneic event; (d) classifying the apneic event as central, obstructive or mixed based on the measured values for TCD/VT and PR according to the following criteria: ______________________________________
TCD/VT PR
(× 10) (× 100) Type of Apnea
______________________________________
about 10-about 15
> about 50 Central
≦ about 50
Mixed
about 16-about 19
> about 50 Central
about 40-about 49
Mixed
< about 39 Obstructive
about 20- about 25
≧ about 55
Central
< about 55 Mixed or
Obstructive
≧ about 25
> about 60 Central
about 40-about 59
Mixed
< about 39 Obstructive
______________________________________
Claim 7
Independent Claim
127 words
A method for differentiating among central, obstructive and mixed apneas in a subject comprising (a) determining the existence of an apneic event; (b) measuring TCD/VT during said apneic event; (c) measuring PR during said apneic event; (d) classifying the apneic event as central, obstructive or mixed based on the measured values for TCD/VT and PR according to the following criteria: ______________________________________
TCD/VT PR
(× 10) (× 100) Type of Apnea
______________________________________
about 10-about 15
> about 50 Central
≦ about 50
Mixed
about 16-about 19
> about 50 Central
about 40-about 49
Mixed
< about 39 Obstructive
about 20- about 25
≧ about 55
Central
< about 55 Mixed or
Obstructive
≧ about 25
> about 60 Central
about 40-about 59
Mixed
< about 39 Obstructive
______________________________________
Claim 8
Dependent Claim
74 words
The method according to claim 1, further comprising measuring intrapleural pressure during said apneic event and confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and confirming classification of said event or a component thereof as an obstructive apnea if a change in intrapleural is recorded during said event or said component thereof, respectively.
Claim 9
Independent Claim
119 words
An apparatus for differentiating among central, obstructive and mixed apneas in a subject comprising (a) means for determining the existence of an apneic event; (b) means for measuring TCD/VT during said apneic event; (c) means for measuring PR during said apneic event; (d) means for classifying the apneic event as central, obstructive or mixed based on the measured values for TCD/VT and PR according to the following criteria: ______________________________________
TCD/VT PR
(× 10) (× 100) Type of Apnea
______________________________________
about 10-about 15
> about 50 Central
≦ about 50
Mixed
about 16-about 19
> about 50 Central
about 40-about 49
Mixed
< about 39 Obstructive
about 20-about 25
≧ about 55
Central
< about 55 Mixed or
Obstructive
______________________________________
Claim 10
Independent Claim
119 words
An apparatus for differentiating among central, obstructive and mixed apneas in a subject comprising (a) means for determining the existence of an apneic event; (b) means for measuring TCD/VT during said apneic event; (c) means for measuring PR during said apneic event; (d) means for classifying the apneic event as central, obstructive or mixed based on the measured values for TCD/VT and PR according to the following criteria: ______________________________________
TCD/VT PR
(× 10) (× 100) Type of Apnea
______________________________________
about 10-about 15
> about 50 Central
≦ about 50
Mixed
about 16-about 19
> about 50 Central
about 40-about 49
Mixed
< about 39 Obstructive
about 20-about 25
≧ about 55
Central
< about 55 Mixed or
Obstructive
______________________________________
Claim 11
Dependent Claim
76 words
The apparatus according to claim 2, further comprising means for measuring intrapleural pressure during said apneic event for confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and confirming classification of said event or component thereof as an obstructive apnea if a change in intrapleural pressure is recorded during said event or said component thereof, respectively.
Claim 12
Independent Claim
174 words
An apparatus for differentiating among central, obstructive and mixed apeneas in a subject comprising (a) means for determining the existence of an apneic event; (b) means for measuring TCD during said apneic event and providing a signal indicative thereof; (c) means for measuring the SUM (VT) during said apneic event and providing a sigal indicative thereof; (d) means for detecting the slopes of said TCD and SUM (VT) signals; and (e) means for classifying an event as a central apneic event when the slopes of said TCD and SUM (VT) signals are substantially the same, as an obstructive apneic event when the slope of said TCD signal is different from the slope of said SUM (VT) signal during substantially said entire apneic event, and as a mixed apneic event when the slopes of said TCD and SUM (VT) signals are substantially the same for a portion of said apneic event and the slope of said TCD signal is different from the slope of said SUM (VT) signal during another portion of said apneic event.
Claim 13
Independent Claim
174 words
An apparatus for differentiating among central, obstructive and mixed apeneas in a subject comprising (a) means for determining the existence of an apneic event; (b) means for measuring TCD during said apneic event and providing a signal indicative thereof; (c) means for measuring the SUM (VT) during said apneic event and providing a sigal indicative thereof; (d) means for detecting the slopes of said TCD and SUM (VT) signals; and (e) means for classifying an event as a central apneic event when the slopes of said TCD and SUM (VT) signals are substantially the same, as an obstructive apneic event when the slope of said TCD signal is different from the slope of said SUM (VT) signal during substantially said entire apneic event, and as a mixed apneic event when the slopes of said TCD and SUM (VT) signals are substantially the same for a portion of said apneic event and the slope of said TCD signal is different from the slope of said SUM (VT) signal during another portion of said apneic event.
Claim 14
Dependent Claim
75 words
The apparatus according to claim 9, further comprising means for measuring PR during said apneic event and means for confirming the classification of said apneic event as a central apneic event if PR is about 98 to about 99, and means for confirming said apneic event as an obstructive apneic event if PR is less than about 97, and confirming said apneic event as a mixed apneic event if PR is less than about 97.
Claim 15
Dependent Claim
81 words
The apparatus according to claim 9, further comprising means for measuring intrapleural pressure during said apneic event and means for confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and means for confirming classification of said event or a component thereof as an obstructive apnea if a change in intrapleural pressure is recorded during said event or said component thereof, respectively.
Claim 16
Dependent Claim
81 words
The apparatus according to claim 10, further comprising means for measuring intrapleural pressure during said apneic event and means for confirming classification of said event or a component thereof as a central apnea if no changes in intrapleural pressure are recorded during said event or said component thereof, respectively, and means for confirming classification of said event or a component thereof as an obstructive apnea if a change in intrapleural pressure is recorded during said event or said component thereof, respectively.
References Cited (Backward Citations)
GB1472650A
Cited
US4269195A
Cited
US4267845A
Cited
US4258718A
Cited
GB2061735A
Cited
NL7908206A
Cited
US4373534A
Cited
EP0078677A2
Cited
GB2142246A
Cited
US4686999A
Cited
US4648407A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-10-18 | 1992-04-18 | 1992-10-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-10-18 | 1996-04-18 | 1996-10-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-10-18 | 2000-04-18 | 2000-10-18 | $7700.00 | Window Closed / Lapsed |