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US4671797A
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Heterologous arterial biograft and biological material treating process
Assignee: Individual
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Filing: 1985-09-20
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Granted: 1987-06-09
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Expires: 2005-09-20
Abstract
Abstract This invention concerns a heterologous arterial biograft comprehending a heterologous biological material-made arterial duct, having its branches bound together (through micro technique) and keeping to a great extent its natural characteristics after submitted to a complete curing by a diabasic acid aldehyde aqueous balanced solution. The arterial duct shall preferably be a swine's or bovine's internal mammary artery.
Inventors
- 👤 Mario O. Vrandecic Pedero
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 21:57
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3625; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/062; A61K; A61K35/00; A61K35/12; A61K35/44; A61L27/3683; A61L27/3687; A61L27/50; A61L27/507
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
179 words
Biological material treating process, characterized by the taking of an animal artery, followed by the immediate binding (through micro technique) of every arterial branch; treatment of the bound duct to complete curing in a diabasic acid (to be selected out of succinic and glutaric acids--the glutaric acid to be preferred) aqueous aldehyde balanced solution that shall be kept within a concentration range extending from 0.001% to about 3% and including monomeric and polymeric free anhydride glutaric aldehydes having a monomer-polymer ratio of about 3:1 yet excluding unsaturated alpha-beta polymers, the solution to be tamponed with Mg group ions and having a pH above 7 and such an ionic power that the ions are kept in a range of about 250 Å to 300 Å, as spectrophotometrically proven; the solution to have an approximate 0.02% to 3% fixative to be selected out of the Periodic Table's group 8 metal ammoniacal oxychlorates (preferably Fe and Ru), at a temperature higher than 10° C. but less than the degradation temperature of the bath components until a histopathologically controlled satisfactory curing is obtained.
Claim 2
Dependent Claim
179 words
Biological material treating process, characterized by the taking of an animal artery, followed by the immediate binding (through micro technique) of every arterial branch; treatment of the bound duct to complete curing in a diabasic acid (to be selected out of succinic and glutaric acids--the glutaric acid to be preferred) aqueous aldehyde balanced solution that shall be kept within a concentration range extending from 0.001% to about 3% and including monomeric and polymeric free anhydride glutaric aldehydes having a monomer-polymer ratio of about 3:1 yet excluding unsaturated alpha-beta polymers, the solution to be tamponed with Mg group ions and having a pH above 7 and such an ionic power that the ions are kept in a range of about 250 Å to 300 Å, as spectrophotometrically proven; the solution to have an approximate 0.02% to 3% fixative to be selected out of the Periodic Table's group 8 metal ammoniacal oxychlorates (preferably Fe and Ru), at a temperature higher than 10° C. but less than the degradation temperature of the bath components until a histopathologically controlled satisfactory curing is obtained.
Claim 3
Dependent Claim
22 words
Biological material treating process, as claimed in claim 1, characterized by the fact that the animal artery is an internal mammary artery.
Claim 4
Dependent Claim
20 words
Biological material treating process, as claimed in claim 2, characterized by the fact that the internal mammary artery is swine's.
Claim 5
Dependent Claim
20 words
Biological material treating process, as claimed in claim 2, characterized by the fact that the internal mammary artery is bovine's.
Claim 6
Dependent Claim
59 words
A heterologous arterial biograft comprising an arterial duct made of heterologous biological material, said arterial duct having branches bound together and its integrity preserved so as to retain original elasticity within a 40% to 60% range and wall inner surface homogeneity within a 80% to 95% range, wherein the heterologous biological arterial duct is an animal internal mammary artery.
Claim 7
Dependent Claim
59 words
A heterologous arterial biograft comprising an arterial duct made of heterologous biological material, said arterial duct having branches bound together and its integrity preserved so as to retain original elasticity within a 40% to 60% range and wall inner surface homogeneity within a 80% to 95% range, wherein the heterologous biological arterial duct is an animal internal mammary artery.
Claim 8
Dependent Claim
18 words
A heterologous arterial biograft according to claim 5, wherein the internal mammary artery is a swine mammary artery.
Claim 9
Dependent Claim
18 words
A heterologous arterial biograft according to claim 5, wherein the internal mammary artery is a bovine mammary artery.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-08 | 1990-12-08 | 1991-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-08 | 1994-12-08 | 1995-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-08 | 1998-12-08 | 1999-06-09 | $7700.00 | Window Closed / Lapsed |