Patent US4664125A successfully refreshed from Google Patents.
US4664125A
Expired / Lapsed
US
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Flow-occluding method for the diagnosis of heart conditions
Assignee: Individual
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Filing: 1986-05-30
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Granted: 1987-05-12
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Expires: 2006-05-30
Abstract
Abstract A method for analyzing the biomechanical behavior of the cardiac muscle and for diagnosing pathological conditions of the heart. The apparatus measures and records the rise and fall of intra-ventricular isovolumetric pressure monitored by a transducer installed at the tip of a cardiac catheter. The pressure versus time recordings during both the systolic and diastolic phases are mathematically analyzed, and two parameters indicative of the biomechanical conditions of the muscle are derived. The parameters are then plotted against each other on a map in which diagnostic zones of various normal and pathological heart conditions are delineated. The cardiac catheter is fitted with a balloon inflation valve used to close the aortic port during a single heartbeat in order to override the aortic valve and maintain the isovolumetric condition during contraction and relaxation of the cardiac muscle organ.
Inventors
- 👤 John G. Pinto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 08:03
CPC Classifications
G; G09; G09B; G09B23/00; G09B23/28; A; A61; A61B; A61B5/00; A61B5/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
186 words
A method for analyzing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: introducing a pressure sensor into one of the subject's ventricles; positioning a balloon inflation valve in the discharge port of said ventricle; closing said valve during at least one cycle of systolic or diastolic pressure; recording the pressure values derived from the sensor during said cycle; plotting said values in relation to time; and mathematically analysing said plotted values and deriving at least one parameter indicative of the condition of the cardiac muscle from the shape of the curve representing the variations of said values during said cycle by interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to a phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter indicative of the excitation-contraction delay, and x represents a second parameter indicative of the inotropic characteristic of the muscle; and computing the x and y parameters which most closely fit the curve.
Claim 2
Independent Claim
186 words
A method for analyzing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: introducing a pressure sensor into one of the subject's ventricles; positioning a balloon inflation valve in the discharge port of said ventricle; closing said valve during at least one cycle of systolic or diastolic pressure; recording the pressure values derived from the sensor during said cycle; plotting said values in relation to time; and mathematically analysing said plotted values and deriving at least one parameter indicative of the condition of the cardiac muscle from the shape of the curve representing the variations of said values during said cycle by interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to a phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter indicative of the excitation-contraction delay, and x represents a second parameter indicative of the inotropic characteristic of the muscle; and computing the x and y parameters which most closely fit the curve.
Claim 3
Dependent Claim
36 words
The method claimed in claim 1, wherein the step of interpreting comprises: computing paired values of said parameters corresponding to a curve of the phenomenological model equation which most closely fits the variations of said signals.
Claim 4
Dependent Claim
48 words
The method claimed in claim 2, wherein said step of interpreting comprises computing a first set of values for said parameters corresponding to the signal recorded during the systolic phase, and a second set of values for said parameters corresponding to the signal recorded during the diastolic phase.
Claim 5
Dependent Claim
17 words
The method claimed in claim 3 which further comprises plotting one of said parameters against the other.
Claim 6
Dependent Claim
31 words
The method claimed in claim 4 wherein the step of plotting comprises forming a diagnostic map having the scaled value of each of said parameters as respective vertical and horizontal coordinates.
Claim 7
Dependent Claim
38 words
The method claimed in claim 5 which further comprises delineating in said map various zones corresponding to pathological muscle conditions; and placing on said map at least one mark having for coordinates the calculated values of said parameters.
Claim 8
Dependent Claim
35 words
The method claimed in claim 4 which further comprises: storing a plurality of diagnosis messages; addressing at least one of said stored messages in function of said first and second parameters; and displaying said message.
Claim 9
Dependent Claim
54 words
The method claimed in claim 2, wherein the step of introducing a pressure sensor comprises introducing a catheter equipped with a pressure sensor in the left ventricle through the aorta; and the step of positioning a balloon inflation valve comprises installing said valve along said catheter distally from said sensor behind the aortic valve.
Claim 10
Dependent Claim
55 words
The method claimed in claim 2, wherein the step of introducing a pressure sensor comprises introducing a catheter equipped with a pressure sensor through a pulmonary artery into the right ventricle; and the step of positioning a balloon inflation valve comprises intalling said valve along said catheter distally from said sensor behind the pulmonary valve.
References Cited (Backward Citations)
US4223682A
Cited
US4592364A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-05-11 | 1990-11-10 | 1991-05-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-05-11 | 1994-11-10 | 1995-05-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-05-11 | 1998-11-10 | 1999-05-12 | $7700.00 | Window Closed / Lapsed |