US4592364A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for the diagnosis of heart conditions
Assignee: Individual
•
Filing: 1984-05-10
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Granted: 1986-06-03
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Expires: 2004-05-10
Abstract
Abstract An apparatus for analyzing the biomechanical behaviour of the cardiac muscle and for diagnosing pathological conditions of the heart. The apparatus measures and records the rise and fall of intra-ventricular pressure monitored by a transducer installed in a cardiac catheter or in an arterial probe. The pressure versus time recordings during both the systolic and diastolic phases are mathematically analyzed, and two parameters indicative of the biomechanical conditions of the muscle are derived. The parameters are then plotted against each other on a map in which diagnostic zones of various normal and pathological heart conditions are delineated.
Inventors
- 👤 John G. Pinto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:09
CPC Classifications
G; G09; G09B; G09B23/00; G09B23/28; A; A61; A61B; A61B5/00; A61B5/02
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
199 words
An apparatus for analysing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: pressure sensitive means shaped and dimensioned to monitor the variation of blood pressure in one part of the subject's cardio-vascular system, and for generating electrical signals proportional to said blood pressure; means responsive to said electrical signals for recording a plurality of values corresponding to successive blood pressure measurements during at least one cycle of the subject's systolic or diastolic pressure phase in relation to time; electrical means for analysing said values and for mathematically deriving at least one critical parameter from the shape of the curve representing the plotting of said values versus time during said cycle and for interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to the phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter, indicative of the excitation-contraction delay, and x represents the second parameter indicative of the inotropic characteristic of the muscle; and means for computing the x and y parameters which most closely fit the curve.
Claim 2
Independent Claim
199 words
An apparatus for analysing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: pressure sensitive means shaped and dimensioned to monitor the variation of blood pressure in one part of the subject's cardio-vascular system, and for generating electrical signals proportional to said blood pressure; means responsive to said electrical signals for recording a plurality of values corresponding to successive blood pressure measurements during at least one cycle of the subject's systolic or diastolic pressure phase in relation to time; electrical means for analysing said values and for mathematically deriving at least one critical parameter from the shape of the curve representing the plotting of said values versus time during said cycle and for interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to the phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter, indicative of the excitation-contraction delay, and x represents the second parameter indicative of the inotropic characteristic of the muscle; and means for computing the x and y parameters which most closely fit the curve.
Claim 3
Dependent Claim
19 words
The apparatus claimed in claim 1 which further comprises means for plotting one of said parameters against the other.
Claim 4
Dependent Claim
49 words
The apparatus claimed in claim 2 wherein said means for plotting comprises means for forming a map having zones corresponding to various pathological cardiac muscle conditions; and means for placing at least one mark of said map, said mark having coordinates corresponding to the computed values of said parameters.
Claim 5
Dependent Claim
49 words
The apparatus claimed in claim 2 which further comprises: means for storing a plurality of diagnosis messages; means for addressing at least one location in said means for storing as a function of said first and second parameters; and means for displaying the diagnostic message stored at said location.
Claim 6
Dependent Claim
49 words
The apparatus claimed in claim 1 wherein said means for interpreting comprise means for computing a first set of values for said parameters corresponding to the signal recorded during the systolic phase, and a second set of values of said parameters corresponding to signals recorded during the diastolic phase.
Claim 7
Independent Claim
179 words
A method for analysing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: measuring by means of at least one pressure sensor the variation of blood pressure in at least one part of the subject's cardio-vascular system during at least one cycle of systolic or diastolic pressure; recording a plurality of values corresponding to successive blood pressure measurements taken during said cycle; plotting said value in relation to time; mathematically analysing said plotted values and deriving at least one parameter from the shape of the curve representing the variation of said signals during said cycle; interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to the phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter indicative of the excitation-contraction delay, and x represents a second parameter indicative of the inotropic characteristic of the muscle; and computing the x and y parameters which most closely fit the curve.
Claim 8
Independent Claim
179 words
A method for analysing the biomechanical behaviour of a subject's cardiac muscle and for diagnosing its pathological conditions which comprises: measuring by means of at least one pressure sensor the variation of blood pressure in at least one part of the subject's cardio-vascular system during at least one cycle of systolic or diastolic pressure; recording a plurality of values corresponding to successive blood pressure measurements taken during said cycle; plotting said value in relation to time; mathematically analysing said plotted values and deriving at least one parameter from the shape of the curve representing the variation of said signals during said cycle; interpreting said curve as a theoretical pressure-function (P) varying in time (t) with changes of ventricular volume (V) according to the phenomenological model equation: P(V,t)=B(V)t.sup.y e.sup.-xt wherein B is a factor corresponding to the influence of the cardiac muscle size, y represents a first parameter indicative of the excitation-contraction delay, and x represents a second parameter indicative of the inotropic characteristic of the muscle; and computing the x and y parameters which most closely fit the curve.
Claim 9
Dependent Claim
50 words
The method claimed in claim 6 wherein said step of interpreting comprises means for computing a first set of measurements for said parameters corresponding to the signal recorded during the systolic phase, and a second set of measurements for said parameters corresponding to the signal recorded during the diastolic phase.
Claim 10
Dependent Claim
17 words
The method claimed in claim 7 which further comprises plotting one of said parameters against the other.
Claim 11
Dependent Claim
31 words
The method claimed in claim 8 wherein the step of plotting comprises forming a diagnostic map having the scaled measurements of each of said parameters as respective vertical and horizontal coordinates.
Claim 12
Dependent Claim
38 words
The method claimed in claim 9 which further comprises delineating in said map various zones corresponding to pathological muscle conditions; and placing on said map at least one mark having for coordinates the calculated measurements of said parameters.
Claim 13
Dependent Claim
35 words
The method claimed in claim 8 which further comprises: storing a plurality of diagnosis messages; addressing at least one of said stored messages in function of said first and second parameters; and displaying said message.
Claim 14
Dependent Claim
31 words
The method claimed in claim 6 which comprises comparing the measurements of the x and y parameters derived from blood pressure measurements taken from different parts of the subject's cardio-vascular system.
References Cited (Backward Citations)
US4223682A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-06-02 | 1989-12-02 | 1990-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-06-02 | 1993-12-02 | 1994-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-06-02 | 1997-12-02 | 1998-06-03 | $7700.00 | Window Closed / Lapsed |