US4447191A
Expired / Lapsed
US
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Control circuit for a blood fractionation apparatus
Assignee: Baxter International Inc
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Filing: 1981-12-15
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Granted: 1984-05-08
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Expires: 2001-12-15
Abstract
Abstract An apparatus for the continuous flow fractionation of whole blood incorporates motor driven whole blood, anticoagulant and replacement pumps, negative and positive pressure monitors, and a dual bubble detector which function in conjunction with a disposable single-use flow system and a hollow fiber filter to separate and collect plasma from whole blood. Operation of the pump motors, pressure monitors and bubble detector is controlled by a control circuit within the apparatus to provide one of several operator-selected operating modes, including run, prime and reinfuse modes. The control circuit provides an alarm which can be cancelled by the operator when certain system parameters fall outside of normal operating limits, and interrupts operation of the pumps when the parameters exceed maximum limits. A failsafe circuit independent of the control circuits interrupts power to the pump motors in the event the motors do not stop upon detection of a bubble or fluid absence in the flow system.
Inventors
- 👤 Arnold C. Bilstad
- 👤 John T. Foley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 17:06
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/34; A61M1/3496; A61M1/342; A61M1/3424; A61M1/3437
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
229 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a flip-flop responsive to applied tachometer pulses from the pump motor for producing an alarm control signal; a series-parallel counter having a reset input, a clock input and a series/parallel enable input, said counter requiring a predetermined number of applied clock pulses following application of a serial enabling signal for producing an output; means for applying said flip-flop output signal to said parallel-serial enable input to enable said counter to a serial mode upon occurrence of said tach pulses; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 2
Dependent Claim
229 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a flip-flop responsive to applied tachometer pulses from the pump motor for producing an alarm control signal; a series-parallel counter having a reset input, a clock input and a series/parallel enable input, said counter requiring a predetermined number of applied clock pulses following application of a serial enabling signal for producing an output; means for applying said flip-flop output signal to said parallel-serial enable input to enable said counter to a serial mode upon occurrence of said tach pulses; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 3
Dependent Claim
26 words
A blood fractionation apparatus as defined in claim 1 wherein said series-parallel counter is a programmable counter, and a predetermined count is parallel-loaded into said counter.
Claim 4
Dependent Claim
30 words
A blood fractionation apparatus as defined in claim 2 wherein said programmable counter is clocked at a one second rate, and said delay period is equal to said parallel-loaded count.
Claim 5
Dependent Claim
22 words
A blood fractionation apparatus as defined in claim 3 wherein said parallel-loaded count is four and said delay period is four seconds.
Claim 6
Dependent Claim
255 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a flip-flop responsive to applied tachometer pulses from the pump motor for producing an alarm control signal; a series-parallel programmable counter having a reset input, a clock input, a parallel data input and a serial/parallel enable input, said counter producing an output upon counting down from a parallel-loaded count to zero in the absence of a reset signal and following application of a serial enabling signal; means for applying a predetermined initial count signal to said parallel data input; means for applying said flip-flop output signal to said parallel-serial enable input to enable said counter to a serial mode upon occurrence of said tach pulses; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 7
Dependent Claim
255 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a flip-flop responsive to applied tachometer pulses from the pump motor for producing an alarm control signal; a series-parallel programmable counter having a reset input, a clock input, a parallel data input and a serial/parallel enable input, said counter producing an output upon counting down from a parallel-loaded count to zero in the absence of a reset signal and following application of a serial enabling signal; means for applying a predetermined initial count signal to said parallel data input; means for applying said flip-flop output signal to said parallel-serial enable input to enable said counter to a serial mode upon occurrence of said tach pulses; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 8
Dependent Claim
30 words
A blood fractionation apparatus as defined in claim 5 wherein said programmable counter is clocked as a one second rate, and said delay period is equal to said parallel-loaded count.
Claim 9
Dependent Claim
22 words
A blood fractionation apparatus as defined in claim 6 wherein said parallel-loaded count is four and said delay period is four seconds.
Claim 10
Dependent Claim
200 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a series-parallel counter having a reset input, a clock input and a series/parallel enable input, said counter requiring a predetermined number of applied clock pulses following application of a serial enabling signal for producing an output; means responsive to said tachometer pulses for enabling said counter to a serial mode; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 11
Dependent Claim
200 words
In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a series-parallel counter having a reset input, a clock input and a series/parallel enable input, said counter requiring a predetermined number of applied clock pulses following application of a serial enabling signal for producing an output; means responsive to said tachometer pulses for enabling said counter to a serial mode; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.
Claim 12
Dependent Claim
28 words
A blood fractionation apparatus as defined in claim 8 wherein said means for terminating operation of the pump include a flip-flop responsive to the output of said counter.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-05-08 | 1987-11-07 | 1988-05-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-05-08 | 1991-11-07 | 1992-05-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-05-08 | 1995-11-07 | 1996-05-08 | $7700.00 | Window Closed / Lapsed |