US4623718A
Expired / Lapsed
US
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Novel composition of matter of antithrombin III bound to a heparin fragment
Assignee: Pfizer Health AB
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Filing: 1983-06-10
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Granted: 1986-11-18
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Expires: 2003-06-10
Abstract
Abstract Novel chemical compounds which are heparin fragments with a molecular weight of from 2,000 to 5,500 covalently bound to antithrombin III, and their use in medicine.
Inventors
- 👤 Desire J. Collen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:41
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/61; A61P; A61P7/00; A61P7/02; C; C08; C08B; C08B37/00; C08B37/006; C08B37/0063; C08B37/0075
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
16 words
A heparin fragment with a molecular weight of 2,000 to, 5,500 covalently bound to antithrombin III.
Claim 2
Dependent Claim
16 words
A heparin fragment with a molecular weight of 2,000 to, 5,500 covalently bound to antithrombin III.
Claim 3
Dependent Claim
22 words
The heparin fragment bound to antithrombin III of claim 1 wherein the ratio of the heparin fragments to antithrombin III is 1:1.
Claim 4
Dependent Claim
32 words
The heparin fragment bound to antithrombin III of claim 1 wherein the heparin fragment, prior to being covalently bound to the antithrombin III, contains from 1 to 2 amino groups per fragment.
Claim 5
Dependent Claim
32 words
The heparin fragment bound to antithrombin III of claim 1 wherein the heparin fragment, prior to being covalently bound to the antithrombin III, includes one terminal group which contains an aldehyde function.
References Cited (Backward Citations)
US4301153A
Cited
US4213962A
Cited
US4303651A
Cited
US4351938A
Cited
US4386025A
Cited
US4446126A
Cited
US4415559A
Cited
US4526714A
Cited
US4533549A
Cited
EP0137356A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-11-17 | 1990-05-19 | 1990-11-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-11-17 | 1994-05-19 | 1994-11-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-11-17 | 1998-05-19 | 1998-11-18 | $7700.00 | Window Closed / Lapsed |