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US4587268A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of osteitis

Assignee: Ed Geistlich Soehne AG fuer Chemische Industrie
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Filing: 1984-03-08
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Granted: 1986-05-06
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Expires: 2004-03-08
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Abstract

Abstract A composition comprising a resorbable aqueous gel having dissolved or dispersed therein one or more water-soluble medicaments is of use in the treatment of wounds. Such a composition is of use in a method of healing an infection in a cavity in bone or other tissue whereby the resorbable aqueous gel is placed in the cavity and allowed to remain there until resorbed, the aqueous phase of the gel containing the water soluble medicament. The medicament is preferably an antibiotic or a methylol transfer antibacterial.

Inventors

  • 👤 Rolf W. Pfirrmann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:47
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/52; A61F; A61F2/00; A61F2/02; A61F2/28; A61L26/00; A61L26/0061; A61L26/0066; A61L27/36; A61L27/3604; A61L27/3608; A61L27/54; A61L27/58; A61F2/30; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30062; A61F2002/30667; A61F2002/30677; A61F2210/00; A61F2210/0004; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/406

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 53 words
A composition for the treatment of osteitis comprising a flexible solid in granular form adapted to be introduced into a bone cavity, the said solid comprising a resorbable aqueous gel of one or more cross-linked fibrous proteins having dissolved or dispersed therein an antibacterially effective amount of one or more water-soluble antibacterial medicaments.
Claim 2
Dependent Claim 53 words
A composition for the treatment of osteitis comprising a flexible solid in granular form adapted to be introduced into a bone cavity, the said solid comprising a resorbable aqueous gel of one or more cross-linked fibrous proteins having dissolved or dispersed therein an antibacterially effective amount of one or more water-soluble antibacterial medicaments.
Claim 3
Dependent Claim 13 words
A composition as claimed in claim 1 wherein the gel comprises cross-linked gelatin.
Claim 4
Dependent Claim 16 words
A composition as claimed in claim 1 wherein the protein is cross-linked by a methylol-transfer agent.
Claim 5
Dependent Claim 14 words
A composition as claimed in claim 3 wherein the methylol transfer agent comprises formaldehyde.
Claim 6
Dependent Claim 14 words
A composition as claimed in claim 1 wherein the antibacterial medicament comprises an antibiotic.
Claim 7
Dependent Claim 23 words
A composition as claimed in claim 1 wherein the flexible solid is in the form of a granulate in admixture with spongiosa tissue.
Claim 8
Dependent Claim 18 words
A composition as claimed in claim 1 wherein the flexible solid is in the form of a rod.
Claim 9
Dependent Claim 31 words
A method of treating osteitis which comprises introducing into a bone cavity infected with osteitis a flexible solid as claimed in claim 1 and allowing it to remain there until resorbed.
Claim 10
Dependent Claim 16 words
A composition as claimed in claim 1 wherein the antibacterial medicament comprises a methylol-transfer antibacterial agent.

References Cited (Backward Citations)

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US3520949A Cited
US3703575A Cited
US3966908A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-05-05 1989-11-04 1990-05-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-05-05 1993-11-04 1994-05-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-05-05 1997-11-04 1998-05-06 $7700.00 Window Closed / Lapsed

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