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Pharmaceutically acceptable silicon rubber and therapeutical set and the use thereof for surgical embolization

Assignee: Individual
•
Filing: 1982-12-01
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Granted: 1985-11-05
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Expires: 2002-12-01
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Abstract

Abstract A silicon rubber embolization agent used in general as well as cerebral vascular surgery having a component A which is composed of: a linear, low viscosity polysiloxane selected from the group consisting of dialkyl, alkylaryl, alkenylalkyl, and diarylpolysiloxanes having reactive functional groups selected from the group consisting of hydroxyl, acyloxyl, alkoxyl and amino; a low viscosity cyclic dialkylpolysiloxane having the formula [R 2 SiO] 4 , wherein R is alkyl; a pharmaceutically acceptable iodo-containing organosilicium; or a non-metallic, organic X-ray contrast material, and a component B which is a therapeutically acceptable cross-linking catalyst.

Inventors

  • 👤 Emil Pasztor
  • 👤 Laszlo Lazar
  • 👤 Jozsef Nagy
  • 👤 Katalin Pallosy nee Becker

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:36
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/18; A61K; A61K49/00; A61K49/04; A61K49/0433; A61K49/0442; A61L24/00; A61L24/001; A61L24/04; A61L24/046; A61L29/00; A61L29/04; A61L29/06; C; C08; C08K; C08K5/00; C08K5/54; C08L; C08L83/00; C08L83/04; A61B; A61B90/00; A61B90/39; A61L2430/00; A61L2430/36; C08G; C08G77/00; C08G77/04; C08G77/14; C08G77/16; C08G77/18; C08G77/20; C08G77/22; C08G77/26; C08G77/70; Y; Y10; Y10S; Y10S528/00; Y10S528/901

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 78 words
In a method of embolization wherein an occlusion is formed in the vascular system by the vulcanization of an embolization agent in situ the improvement comprising said embolization agent being a silicone rubber component having reactive functional groups selected from the groups consisting of hydroxyl, acyloxyl, alkoxyl, and amino; a cyclic dialkyl-polysiloxane and a pharmaceutically acceptable iodo-containing organosilicium or non-metallic organic X-ray contrast material, and a component B comprising an effective amount of a therapeutically acceptable cross-linking catalyst.
Claim 2
Dependent Claim 78 words
In a method of embolization wherein an occlusion is formed in the vascular system by the vulcanization of an embolization agent in situ the improvement comprising said embolization agent being a silicone rubber component having reactive functional groups selected from the groups consisting of hydroxyl, acyloxyl, alkoxyl, and amino; a cyclic dialkyl-polysiloxane and a pharmaceutically acceptable iodo-containing organosilicium or non-metallic organic X-ray contrast material, and a component B comprising an effective amount of a therapeutically acceptable cross-linking catalyst.

References Cited (Backward Citations)

US3834394A Cited
US3687142A Cited
US4196731A Cited
US4346712A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-11-04 1989-05-06 1989-11-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-11-04 1993-05-06 1993-11-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-11-04 1997-05-06 1997-11-05 $7700.00 Window Closed / Lapsed

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