Patent US4509522A successfully refreshed from Google Patents.
US4509522A
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Infrared optical measurement of blood gas concentrations and fiber optic catheter
Assignee: United States Department of the Navy
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Filing: 1981-12-15
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Granted: 1985-04-09
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Expires: 2001-12-15
Abstract
Abstract A simple compact optical device and method for quickly measuring the concentration of CO and CO 2 , bound to hemoglobin or dissolved in a person's blood using optical techniques which do not require removing a blood sample from the body. It also provides a simple fiber optic device for measuring blood-gas concentrations of critical internal points of the circulatory system such as the aorta.
Inventors
- 👤 Thomas J. Manuccia
- 👤 J. Gary Eden
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:24
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6848; A61B5/145; A61B5/1455; A61B5/1459
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
130 words
A method of determining the absolute concentrations of CO, CO 2 and O 2 in blood comprising the steps of: selectively passing infrared light of near 5.13 μm, 4.3 μm and 9.0 μm through a dimension of blood and measuring magnitudes of transmission at absorption peak wavelengths near 5.13 μm, 4.3 μm and 9.0 μm, corresponding to CO, CO 2 , and O 2 , respectively; comparing said respective transmissions to transmissions through like dimension reference samples of blood whose blood gas concentrations are known; determining the absolute concentrations of CO, CO 2 , and O 2 , biased on the comparison of transmission through the blood dimension at these wavelengths to transmission through the reference blood samples having known concentrations of CO, CO 2 , and O 2 .
Claim 2
Independent Claim
130 words
A method of determining the absolute concentrations of CO, CO 2 and O 2 in blood comprising the steps of: selectively passing infrared light of near 5.13 μm, 4.3 μm and 9.0 μm through a dimension of blood and measuring magnitudes of transmission at absorption peak wavelengths near 5.13 μm, 4.3 μm and 9.0 μm, corresponding to CO, CO 2 , and O 2 , respectively; comparing said respective transmissions to transmissions through like dimension reference samples of blood whose blood gas concentrations are known; determining the absolute concentrations of CO, CO 2 , and O 2 , biased on the comparison of transmission through the blood dimension at these wavelengths to transmission through the reference blood samples having known concentrations of CO, CO 2 , and O 2 .
Claim 3
Independent Claim
95 words
A method of detecting relative concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a dimension of blood, said infrared radiation exiting from the backside of the blood dimension; selectively filtering at near 5.13 μm, 4.3 μm and 9.0 μm the radiation passing from the backside of the blood dimension; measuring the amplitude of the filtered radiation at absorption peak wavelengths of 5.13 μm, 4.3 μm and 9.0 μm as an indication of relative concentration for CO, CO 2 , and O 2 , respectively.
Claim 4
Independent Claim
95 words
A method of detecting relative concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a dimension of blood, said infrared radiation exiting from the backside of the blood dimension; selectively filtering at near 5.13 μm, 4.3 μm and 9.0 μm the radiation passing from the backside of the blood dimension; measuring the amplitude of the filtered radiation at absorption peak wavelengths of 5.13 μm, 4.3 μm and 9.0 μm as an indication of relative concentration for CO, CO 2 , and O 2 , respectively.
Claim 5
Independent Claim
147 words
A method of determining absolute concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a thin section of blood-containing body tissue; selectively filtering at 5.13 μm, 4.3 μm and 9.0 μm wavelengths radiation exiting from the body tissue; measuring respective amplitudes of the filtered radiation at absorption peak wavelengths of 5.13 μm, 4.3 μm and 9.0 μm; and comparing the measured respective amplitudes obtained from measuring like wavelength radiation having passed through similar sections of human body tissues whose blood concentration of CO, CO 2 , and O 2 are known; detemining the absolute concentrations of CO, CO 2 , and O 2 based on the comparison of the radiation passed through the body tissue at these wavelengths to the radiation passed through the body tissues having known concentrations of CO, CO 2 and O 2 .
Claim 6
Independent Claim
147 words
A method of determining absolute concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a thin section of blood-containing body tissue; selectively filtering at 5.13 μm, 4.3 μm and 9.0 μm wavelengths radiation exiting from the body tissue; measuring respective amplitudes of the filtered radiation at absorption peak wavelengths of 5.13 μm, 4.3 μm and 9.0 μm; and comparing the measured respective amplitudes obtained from measuring like wavelength radiation having passed through similar sections of human body tissues whose blood concentration of CO, CO 2 , and O 2 are known; detemining the absolute concentrations of CO, CO 2 , and O 2 based on the comparison of the radiation passed through the body tissue at these wavelengths to the radiation passed through the body tissues having known concentrations of CO, CO 2 and O 2 .
Claim 7
Dependent Claim
98 words
Apparatus for indicating relative concentration of CO in blood comprising: means for directing infrared light through relatively thin blood containing tissue of the human body; filter means allowing a bandpass of around 5.13 μm; said filter means adapted to be located on the backside of the tissue for intercepting light exiting from the tissue; and light detector means for detecting the magnitude of light having passed through said filter means at absorption peaks of around 5.13 μm; whereby the magnitude of light detected by said detector means is proportional to the concentration of carbon monoxide in the blood.
Claim 8
Dependent Claim
98 words
Apparatus for indicating relative concentration of CO in blood comprising: means for directing infrared light through relatively thin blood containing tissue of the human body; filter means allowing a bandpass of around 5.13 μm; said filter means adapted to be located on the backside of the tissue for intercepting light exiting from the tissue; and light detector means for detecting the magnitude of light having passed through said filter means at absorption peaks of around 5.13 μm; whereby the magnitude of light detected by said detector means is proportional to the concentration of carbon monoxide in the blood.
Claim 9
Dependent Claim
169 words
Apparatus for indicating the absolute concentration of carbon monoxide in blood comprising: means for directing light through a relatively thin blood-containing human body tissue; means adapted to be located on the backside of the body tissue for intercepting light exiting from the tissue and splitting the light into two beams of substantially equal magnitude; first filter in one of the beams allowing a bandpass of about 5.13 μm; second filter in the other beam allowing a bandpass of around 5.05 μm; and light detecting means downstream of the first and second filters for detecting light transmitted thereto from the filters; whereby the extent of around 5.05 μm wavelength light transmission through the blood-containing human body tissue is relatively independent of carbon monoxide concentration in the blood, but is dependent upon other characteristics of that body tissue for establishing a reference; and whereby the extent of light of around 5.13 μm wavelengths transmitted through the same blood-containing body tissue defines a carbon monoxide concentration when compared with the reference transmission.
Claim 10
Dependent Claim
169 words
Apparatus for indicating the absolute concentration of carbon monoxide in blood comprising: means for directing light through a relatively thin blood-containing human body tissue; means adapted to be located on the backside of the body tissue for intercepting light exiting from the tissue and splitting the light into two beams of substantially equal magnitude; first filter in one of the beams allowing a bandpass of about 5.13 μm; second filter in the other beam allowing a bandpass of around 5.05 μm; and light detecting means downstream of the first and second filters for detecting light transmitted thereto from the filters; whereby the extent of around 5.05 μm wavelength light transmission through the blood-containing human body tissue is relatively independent of carbon monoxide concentration in the blood, but is dependent upon other characteristics of that body tissue for establishing a reference; and whereby the extent of light of around 5.13 μm wavelengths transmitted through the same blood-containing body tissue defines a carbon monoxide concentration when compared with the reference transmission.
Claim 11
Independent Claim
146 words
A method of detecting absolute concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a dimension of blood; selectively filtering at near 5.13 μm, 4.3 μm and 9.0 μm the radiation passing from the backside of said blood dimension; measuring the respective amplitudes of the filtered radiation at absorption peak wavelengths near 5.13 μm, 4.3 μm and 9.0 μm; and comparing the measured amplitudes against amplitudes obtained by like radiation wavelengths having passed through a like dimension of blood whose CO, CO 2 and O 2 concentrations are known; detecting the absolute concentrations of CO, CO 2 , and O 2 based on the comparison of the radiation passed through the blood dimension at these wavelength to the radiation passed through a blood dimension having known concentrations of CO, CO 2 , and O 2 .
Claim 12
Independent Claim
146 words
A method of detecting absolute concentrations of CO, CO 2 , and O 2 in blood comprising the steps of: passing infrared radiation through a dimension of blood; selectively filtering at near 5.13 μm, 4.3 μm and 9.0 μm the radiation passing from the backside of said blood dimension; measuring the respective amplitudes of the filtered radiation at absorption peak wavelengths near 5.13 μm, 4.3 μm and 9.0 μm; and comparing the measured amplitudes against amplitudes obtained by like radiation wavelengths having passed through a like dimension of blood whose CO, CO 2 and O 2 concentrations are known; detecting the absolute concentrations of CO, CO 2 , and O 2 based on the comparison of the radiation passed through the blood dimension at these wavelength to the radiation passed through a blood dimension having known concentrations of CO, CO 2 , and O 2 .
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-04-08 | 1988-10-08 | 1989-04-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-04-08 | 1992-10-08 | 1993-04-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-04-08 | 1996-10-08 | 1997-04-09 | $7700.00 | Window Closed / Lapsed |