US4482533A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polymeric diffusion matrix containing propranolol
Assignee: Key Pharmaceuticals Inc
•
Filing: 1983-03-28
•
Granted: 1984-11-13
•
Expires: 2003-03-28
Abstract
Abstract A self-supporting polymeric diffusion matrix provides for the sustained release of propranolol in order to deliver said propranolol to a patient. The matrix comprises from about 1 to about 60% by weight of a polar plasticizer, from about 5 to about 20% by weight polyvinylalcohol having a molecular weight from about 50,000 to about 150,000, from about 10 to about 25% by weight polyvinylalcohol having a molecular weight from about 4,000 to about 15,000, from about 2 to about 30% by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of the propanolol to provide a sustained release of said propranolol over a prolonged period.
Inventors
- 👤 Alec D. Keith
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:49
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7084; A61K31/00; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
129 words
A self-supporting polymeric diffusion matrix for the sustained release of propranolol in order to deliver said propranolol to a patient, said matrix comprising from about 1 to about 60% by weight of a polar plasticizer, from about 5 to about 20% by weight polyvinylalcohol having a molecular weight from about 50,000 to about 150,000, from about 10 to about 25% by weight polyvinylalcohol having a molecular weight from about 4,000 to about 15,000, from about 2 to about 30% by weight polyvinylpyrrolidone, a pharmaceutically effective amount of the propranolol to provide a sustained release of said propranolol over a prolonged period, and from about 5 to about 20% by weight of diethanol myristoylamide, effectively functioning to bring the components into solution, said matrix having been formed from said solution.
Claim 2
Dependent Claim
129 words
A self-supporting polymeric diffusion matrix for the sustained release of propranolol in order to deliver said propranolol to a patient, said matrix comprising from about 1 to about 60% by weight of a polar plasticizer, from about 5 to about 20% by weight polyvinylalcohol having a molecular weight from about 50,000 to about 150,000, from about 10 to about 25% by weight polyvinylalcohol having a molecular weight from about 4,000 to about 15,000, from about 2 to about 30% by weight polyvinylpyrrolidone, a pharmaceutically effective amount of the propranolol to provide a sustained release of said propranolol over a prolonged period, and from about 5 to about 20% by weight of diethanol myristoylamide, effectively functioning to bring the components into solution, said matrix having been formed from said solution.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-13 | 1988-05-14 | 1988-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-13 | 1992-05-14 | 1992-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-13 | 1996-05-14 | 1996-11-13 | $7700.00 | Window Closed / Lapsed |