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US4424305A Expired / Lapsed US ⏱️ 0.0 years remaining

Surgical implants formed of polyurethane diacrylate compositions

Assignee: Tyndale Plains Hunter Ltd
•
Filing: 1982-09-01
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Granted: 1984-01-03
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Expires: 2002-09-01
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Abstract

Abstract Surgical implants, intrauterine devices and the like formed of polyurethane diacrylate compositions obtained by reacting a diacrylate in the presence of from about 65 to about 95 weight percent of a hydrophilic polyurethane resin. The compositions will form a hydrogel upon immersion in water and are permeable to gases, ions and other low molecular weight species. The hydrophilic polyurethane diacrylate compositions may be molded to form shaped products that are dimensionally stable after repeated exposure to boiling water and exhibit memory. The shaped products contain distributed therein a desired medicament.

Inventors

  • 👤 Francis E. Gould
  • 👤 Christian W. Johnston

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:52
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/24; A61L15/42; A61L15/60; A61L17/00; A61L17/04; C; C08; C08F; C08F283/00; C08F299/00; C08F299/02; C08F299/06; C08F299/065; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/65; C08G18/66; C08G18/6666; C08G18/667; C08G18/6674; G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; C08G2210/00; H; H01; H01M; H01M50/00; H01M50/40; H01M50/409; H01M50/411; H01M50/414; H01M50/489; Y; Y02; Y02E; Y02E60/00; Y02E60/10; Y10; Y10S; Y10S521/00; Y10S521/905; Y10S528/00; Y10S528/904; Y10S623/00; Y10S623/924

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 77 words
An implant comprising a hydrophilic polyurethane diacrylate composition which will form a hydrogel upon immersion in water and is permeable to gases, ions and other low molecular weight species, which composition is dimensionally stable and exhibits memory, said polyurethane diacrylate composition comprising from about 90 to about 65 weight percent of a hydrophilic polyurethane resin characterized by terminal hydroxyl groups and from about 10 to about 35 weight percent of a diacrylate, said implant containing a medicament.
Claim 2
Dependent Claim 77 words
An implant comprising a hydrophilic polyurethane diacrylate composition which will form a hydrogel upon immersion in water and is permeable to gases, ions and other low molecular weight species, which composition is dimensionally stable and exhibits memory, said polyurethane diacrylate composition comprising from about 90 to about 65 weight percent of a hydrophilic polyurethane resin characterized by terminal hydroxyl groups and from about 10 to about 35 weight percent of a diacrylate, said implant containing a medicament.
Claim 3
Dependent Claim 12 words
The implant of claim 1 wherein said medicament is an antitubercular drug.
Claim 4
Dependent Claim 12 words
The implant of claim 1 wherein said medicament is a drug protagonist.
Claim 5
Dependent Claim 11 words
The implant of claim 1 wherein said medicament is a hormone.
Claim 6
Dependent Claim 11 words
The implant of claim 1 wherein said medicament is a steroid.
Claim 7
Dependent Claim 11 words
The implant of claim 1 wherein said medicament is a vitamin.
Claim 8
Dependent Claim 12 words
The implant of claim 1 in the form of an intrauterine device.
Claim 9
Dependent Claim 12 words
The intrauterine device of claim 7 in the shape of a diaphragm.
Claim 10
Dependent Claim 15 words
The intrauterine device of claim 7 having distributed throughout said polyurethane diacrylate composition a contraceptive.
Claim 11
Dependent Claim 12 words
The intrauterine device of claim 9 wherein said contraceptive is lactic acid.
Claim 12
Dependent Claim 111 words
An implant comprising a hydrophilic polyurethane diacrylate composition which will form a hydrogel upon immersion in water; is permeable to gases, ions and other low molecular weight species; is dimensionally stable and exhibits memory; obtained by the reaction of from about 10 to about 35 weight percent of a diacrylate having the formula: ##STR3## wherein R is selected from the group consisting of hydrogen and the methyl radical and n is a small whole number, such that the average molecular weight of the diacrylate is no greater than 1586; in the presence of from about 90 to about 65 weight percent of a hydrophilic polyurethane resin, said implant containing a medicament.
Claim 13
Dependent Claim 111 words
An implant comprising a hydrophilic polyurethane diacrylate composition which will form a hydrogel upon immersion in water; is permeable to gases, ions and other low molecular weight species; is dimensionally stable and exhibits memory; obtained by the reaction of from about 10 to about 35 weight percent of a diacrylate having the formula: ##STR3## wherein R is selected from the group consisting of hydrogen and the methyl radical and n is a small whole number, such that the average molecular weight of the diacrylate is no greater than 1586; in the presence of from about 90 to about 65 weight percent of a hydrophilic polyurethane resin, said implant containing a medicament.
Claim 14
Dependent Claim 12 words
The implant of claim 11 wherein said medicament is an antitubercular drug.
Claim 15
Dependent Claim 12 words
The implant of claim 11 wherein said medicament is a drug protagonist.
Claim 16
Dependent Claim 11 words
The implant of claim 11 wherein said medicament is a hormone.
Claim 17
Dependent Claim 11 words
The implant of claim 11 wherein said medicament is a steroid.
Claim 18
Dependent Claim 11 words
The implant of claim 11 wherein said medicament is a vitamin.
Claim 19
Dependent Claim 12 words
The implant of claim 11 in the form of an intrauterine device.
Claim 20
Dependent Claim 12 words
The intrauterine device of claim 17 in the shape of a diaphragm.
Claim 21
Dependent Claim 15 words
The intrauterine device of claim 17 having distributed throughout said polyurethane diacrylate composition a contraceptive.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-01-02 1987-07-04 1988-01-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-01-02 1991-07-04 1992-01-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-01-02 1995-07-04 1996-01-03 $7700.00 Window Closed / Lapsed

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