US4418208A
Expired / Lapsed
US
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N-Substituted iminodiacetic acids
Assignee: Bracco International BV
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Filing: 1982-06-16
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Granted: 1983-11-29
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Expires: 2002-06-16
Abstract
Abstract Complexes of technetium-99m and a compound selected from the group having the formula ##STR1## or a pharmaceutically acceptable, water soluble salt thereof wherein R 1 and R 4 are each independently hydrogen, methyl or ethyl; one of R 2 and R 3 is alkyl of 1 to 4 carbons and the other is bromine or iodine; and n is 0, 1 or 2, are useful for the external imaging of the hepatobiliary system.
Inventors
- 👤 Adrian Nunn
- 👤 Michael Loberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:56
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/0474; A61K51/0478; A61K2123/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
36 words
A compound having the formula ##STR6## or a pharmaceutically acceptable, water soluble salt thereof, wherein one of R 2 and R 3 is methyl and the other is bromine and n is 0, 1 or 2.
Claim 2
Dependent Claim
36 words
A compound having the formula ##STR6## or a pharmaceutically acceptable, water soluble salt thereof, wherein one of R 2 and R 3 is methyl and the other is bromine and n is 0, 1 or 2.
Claim 3
Dependent Claim
11 words
A compound in accordance with claim 1 wherein n is 0.
Claim 4
Dependent Claim
21 words
A compound having the formula ##STR7## or a pharmaceutically acceptable, water soluble salt thereof, wherein n is 0, 1 or 2.
Claim 5
Dependent Claim
21 words
A compound having the formula ##STR7## or a pharmaceutically acceptable, water soluble salt thereof, wherein n is 0, 1 or 2.
Claim 6
Dependent Claim
44 words
A composition comprising a stannous reducing agent and a compound having the formula ##STR8## or a pharmaceutically acceptable, water soluble salt thereof, wherein one of R 2 and R 3 is methyl and the other is bromine and n is 0, 1 or 2.
Claim 7
Dependent Claim
44 words
A composition comprising a stannous reducing agent and a compound having the formula ##STR8## or a pharmaceutically acceptable, water soluble salt thereof, wherein one of R 2 and R 3 is methyl and the other is bromine and n is 0, 1 or 2.
Claim 8
Dependent Claim
11 words
A composition in accordance with claim 4 wherein n is 0.
Claim 9
Dependent Claim
29 words
A composition comprising a stannous reducing agent and a compound having the formula ##STR9## or a pharmaceutically acceptable, water soluble salt thereof, wherein n is 0, 1 or 2.
Claim 10
Dependent Claim
29 words
A composition comprising a stannous reducing agent and a compound having the formula ##STR9## or a pharmaceutically acceptable, water soluble salt thereof, wherein n is 0, 1 or 2.
Claim 11
Dependent Claim
11 words
A composition in accordance with claim 6 wherein n is 0.
Claim 12
Dependent Claim
9 words
The compound in accordance with claim 2, 2,2'-[[2-[(3-bromo-2,4,6-trimethylphenyl)amino]-2-oxoethyl]imino]bisacetic acid.
Claim 13
Dependent Claim
9 words
The compound in accordance with claim 3, 2,2'-[[2-[(4-bromo-3-methylphenyl)amino]-2-oxoethyl]imino]bisacetic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-11-28 | 1987-05-30 | 1987-11-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-11-28 | 1991-05-30 | 1991-11-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-11-28 | 1995-05-30 | 1995-11-29 | $7700.00 | Window Closed / Lapsed |