Patent US4404970A successfully refreshed from Google Patents.
US4404970A
Expired / Lapsed
US
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Hemostatic article and methods for preparing and employing the same
Assignee: SUPERSTAT Corp
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Filing: 1980-07-22
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Granted: 1983-09-20
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Expires: 2000-07-22
Abstract
Abstract An improved hemostatic article is made by combining collagen or a collagen-like substance with a pad or sponge. The thusly modified pad or sponge is employed to control or terminate bleeding.
Inventors
- 👤 Philip N. Sawyer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:12
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78; A; A61; A61K; A61K38/00; A61L; A61L2400/00; A61L2400/04; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
132 words
A hemostatic article prepared by a method comprising modifying one of the group consisting of a collagen substance or collagen-like substance by dissolving the substance in water and modifying the thereby dissolved substance to render the surface charge thereof effectively more positive than prior to modification whereby to provide augmented hemostatic properties thereto and freezing and drying the thereby modified substance in a porous body, said porous body having a normal structural strength and composition which is modified by said modified substance, the modified substance being blood-soluble such that upon subjecting the thereby modified substance in the porous body to blood, the modified substance goes into solution therein; the supporting body being so constructed and arranged that it resumes its normal strength and composition after the modified substance has gone into solution.
Claim 2
Dependent Claim
132 words
A hemostatic article prepared by a method comprising modifying one of the group consisting of a collagen substance or collagen-like substance by dissolving the substance in water and modifying the thereby dissolved substance to render the surface charge thereof effectively more positive than prior to modification whereby to provide augmented hemostatic properties thereto and freezing and drying the thereby modified substance in a porous body, said porous body having a normal structural strength and composition which is modified by said modified substance, the modified substance being blood-soluble such that upon subjecting the thereby modified substance in the porous body to blood, the modified substance goes into solution therein; the supporting body being so constructed and arranged that it resumes its normal strength and composition after the modified substance has gone into solution.
Claim 3
Dependent Claim
15 words
The article as claimed in claim 1 wherein the substance is modified by non-covalent modification.
Claim 4
Dependent Claim
12 words
The article as claimed in claim 2 wherein the substance is lyophilized.
Claim 5
Dependent Claim
18 words
The article as claimed in claim 3 wherein the substance is gelatin which is treated with hydrochloric acid.
Claim 6
Dependent Claim
17 words
The article as claimed in claim 3 wherein the substance is gelatin which is treated with ethylenediamine.
Claim 7
Dependent Claim
14 words
The article as claimed in claim 3, wherein the porous body is water insoluble.
Claim 8
Dependent Claim
15 words
The article as claimed in claim 1 wherein the substance is modified by covalent modification.
Claim 9
Dependent Claim
12 words
The article as claimed in claim 7 wherein the substance is lyophilized.
Claim 10
Dependent Claim
18 words
The article as claimed in claim 8 wherein the substance is gelatin which treated with NH 4 Cl.
Claim 11
Dependent Claim
17 words
The article as claimed in claim 8 wherein the substance is gelatin which is treated with HCl.
Claim 12
Dependent Claim
14 words
The article as claimed in claim 5, wherein the porous body is water insoluble.
Claim 13
Dependent Claim
14 words
The article as claimed in claim 1 wherein the porous body is water insoluble.
References Cited (Backward Citations)
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US3157524A
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US3742955A
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US3810473A
Cited
US4022203A
Cited
US4066083A
Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-09-19 | 1987-03-21 | 1987-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-09-19 | 1991-03-21 | 1991-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-09-19 | 1995-03-21 | 1995-09-20 | $7700.00 | Window Closed / Lapsed |