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US4364929A
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Germicidal colloidal lubricating gels and method of producing the same
Assignee: Purdue Frederick Co
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Filing: 1980-04-30
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Granted: 1982-12-21
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Expires: 2000-04-30
Abstract
Abstract Germicidal properties are provided for colloidal lubricating gels without destruction of the physical properties of the colloidal gel by the incorporation therein of an iodophor within strict limits as to the quantities and relative quantities of the iodophor-former, the iodine and the gel-forming colloid. These germicidal colloidal lubricating gels remain stable and retain their germicidal effectiveness. As a result, these compositions can be used for the lubrication of catheters and other instruments to facilitate their insertion into a body cavity and because these compositions do not cause pain or irritation their use reduces the risk of infection and tissue-trauma.
Inventors
- 👤 Ernest J. Sasmor
- 👤 Kenneth G. Rothwell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:01
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61L; A61L29/00; A61L29/14; A61L29/16; A61L2300/00; A61L2300/10; A61L2300/106; A61L2300/40; A61L2300/404; A61L2300/452
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
80 words
An aqueous germicidal colloidal lubricating gel, comprising water, 0.05-2% by weight iodine, 0.5-7.5% by weight of a physiologically compatible gel-forming colloid selected from the group consisting of methylcellulose, carboxymethylcellulose, hydroxyalkylcellulose, gum karaya, alginic acid, glycol esters of alginic acid, gum guar, pslyllium, acacia and tragacanth, an iodophor-former selected from the group consisting of 0.5-2 parts by weight per part of said colloid of polyvinylpyrrolidone and 0.3-4 parts by weight per part of said colloid of nonylphenoxypoly-(ethyleneoxy)-ethanol and polyoxypropylenepoly-(oxy-propylene) poly-oxyethylene copolymers.
Claim 2
Dependent Claim
80 words
An aqueous germicidal colloidal lubricating gel, comprising water, 0.05-2% by weight iodine, 0.5-7.5% by weight of a physiologically compatible gel-forming colloid selected from the group consisting of methylcellulose, carboxymethylcellulose, hydroxyalkylcellulose, gum karaya, alginic acid, glycol esters of alginic acid, gum guar, pslyllium, acacia and tragacanth, an iodophor-former selected from the group consisting of 0.5-2 parts by weight per part of said colloid of polyvinylpyrrolidone and 0.3-4 parts by weight per part of said colloid of nonylphenoxypoly-(ethyleneoxy)-ethanol and polyoxypropylenepoly-(oxy-propylene) poly-oxyethylene copolymers.
Claim 3
Dependent Claim
27 words
Composition according to claim 1 wherein said iodophor-former is polyvinylpyrrolidone and is present in an amount of 0.5-2 parts by weight per each part of said colloid.
Claim 4
Dependent Claim
28 words
Composition according to claim 1 wherein said iodophor-former is a surfactant and is present in an amount of 0.3-4 parts by weight per each part of said colloid.
Claim 5
Dependent Claim
50 words
Method of inserting a medical instrument into a body cavity without substantial irritation or pain and with reduced risk of infection and tissue trauma, which comprises lubricating the instrument with the aqueous germicidal colloidal lubricating gel of claim 1, and inserting the thus lubricated instrument into the selected body cavity.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-12-20 | 1986-06-21 | 1986-12-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-12-20 | 1990-06-21 | 1990-12-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-12-20 | 1994-06-21 | 1994-12-21 | $7700.00 | Window Closed / Lapsed |