US4314935A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for recovering interferon
Assignee: Tanabe Pharma Corp
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Filing: 1980-08-06
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Granted: 1982-02-09
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Expires: 2000-08-06
Abstract
Abstract A process for recovering interferon which comprises contacting a solution containing an interferon produced by the induced cells of human origin with a water-insolubilized sulfated polysaccharide to allow the interferon to be adsorbed on the water-insolubilized sulfated polysaccharide and then selectively eluting the interferon with an aqueous solution of an inorganic salt.
Inventors
- 👤 Yahiro Uemura
- 👤 Hirofumi Arimura
- 👤 Hiroshi Morise
- 👤 Satoshi Funakoshi
- 👤 Tadakazu Suyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 20:55
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; C07K14/555; Y; Y10; Y10S; Y10S435/00; Y10S435/811; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/837; Y10S530/838; Y10S530/848
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
48 words
A process for recovering interferon, which comprises contacting a solution containing interferon produced by the induced cells of human origin with a water-insolubilized heparin to allow the interferon to be adsorbed on the water-insolubilized heparin and then eluting the interferon with an aqueous solution of an inorganic salt.
Claim 2
Dependent Claim
48 words
A process for recovering interferon, which comprises contacting a solution containing interferon produced by the induced cells of human origin with a water-insolubilized heparin to allow the interferon to be adsorbed on the water-insolubilized heparin and then eluting the interferon with an aqueous solution of an inorganic salt.
Claim 3
Dependent Claim
20 words
A process according to claim 1, wherein the inorganic salt is sodium chloride, potassium chloride, calcium chloride or sodium sulfate.
Claim 4
Dependent Claim
18 words
A process according to claim 1, wherein the cells of human origin are leukocytes, lymphocytes or reticuloendothelial cells.
Claim 5
Dependent Claim
15 words
A process according to claim 3, wherein the cells of human origin are Namalva strain.
Claim 6
Dependent Claim
16 words
A process according to claim 1, wherein the water-insolubilized heparin is washed with water before use.
Claim 7
Dependent Claim
22 words
A process according to claim 5, wherein the water-insolubilized heparin is kept equilibrated with a buffer solution of pH 5 to 10.
Claim 8
Dependent Claim
26 words
A process according to claim 1, wherein the salt concentration and pH of the aqueous solution is 0.05 to 2 moles/liter and 5 to 10, respectively.
References Cited (Backward Citations)
US3144390A
Cited
US4172071A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-02-08 | 1985-08-10 | 1986-02-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-02-08 | 1989-08-10 | 1990-02-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-02-08 | 1993-08-10 | 1994-02-09 | $7700.00 | Window Closed / Lapsed |