US3144390A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the purification of interferon
Assignee: National Research Development Corp UK
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Filing: 1961-06-21
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Granted: 1964-08-11
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Expires: 1981-06-21
Abstract
No abstract record available.
Inventors
- 👤 Derek C Burke
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:39
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; C07K14/555; B; B01; B01D; B01D61/00; B01D61/24; B01D61/243
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
101 words
A PROCESS FOR THE PURIFICATION OF INTERFERON WHICH COMPRISES SUBJECTING A CONCENTRATE OF INTERFERON IN A SALT SOLUTION TO PRESSURE DIALYSIS TOPRODUCE A SOLUTION CONTAINING A LARGELY INCREASED CONTENT OF INTERFERON, SUBJECTING THE SOLUTION TO CHROMATOGRAPHY ON SULPHOMETHYLCELLULOSE AT A PH OF ABOUT 2 WITH AN INCREASING CHLORIDE GRADIENT, SUBJECT THE SOLUTION TO CHROMATOGRAPHY N DIETHYLAMINOETHYLCELLULOSE WITH AN INCREASING PHOSPHATE GRADIENT IN TWO STAGES ONE OF WHICH IS CONDUCTED AT A PH OF 5.5 TO 8.0 AND THE OTHER OF WHICH IS CONDUCTED AT A PH OF 4.4 TO 4.6 AND RECOVERING INTERFERON OF INCREASED PURITY AND CONCENTRATION FORM THE CHROMATOGRAMS.
Claim 2
Dependent Claim
101 words
A PROCESS FOR THE PURIFICATION OF INTERFERON WHICH COMPRISES SUBJECTING A CONCENTRATE OF INTERFERON IN A SALT SOLUTION TO PRESSURE DIALYSIS TOPRODUCE A SOLUTION CONTAINING A LARGELY INCREASED CONTENT OF INTERFERON, SUBJECTING THE SOLUTION TO CHROMATOGRAPHY ON SULPHOMETHYLCELLULOSE AT A PH OF ABOUT 2 WITH AN INCREASING CHLORIDE GRADIENT, SUBJECT THE SOLUTION TO CHROMATOGRAPHY N DIETHYLAMINOETHYLCELLULOSE WITH AN INCREASING PHOSPHATE GRADIENT IN TWO STAGES ONE OF WHICH IS CONDUCTED AT A PH OF 5.5 TO 8.0 AND THE OTHER OF WHICH IS CONDUCTED AT A PH OF 4.4 TO 4.6 AND RECOVERING INTERFERON OF INCREASED PURITY AND CONCENTRATION FORM THE CHROMATOGRAMS.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1967-08-11 | 1968-02-10 | 1968-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1971-08-11 | 1972-02-10 | 1972-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1975-08-11 | 1976-02-10 | 1976-08-11 | $7700.00 | Window Closed / Lapsed |