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US4308250A Expired / Lapsed US ⏱️ 0.0 years remaining

Sustained drug release device

Assignee: Pfizer Inc
•
Filing: 1980-12-09
•
Granted: 1981-12-29
•
Expires: 2000-12-09
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Abstract

Abstract A device for oral administration to a ruminant animal includes a veterinary medicament, such as an anthelmintic, uniformly dispersed throughout an erodable sheet comprising an ethylene-vinylacetate copolymer. The sheet is rolled up and stuck together with adhesive backed paper strips for administration, and unrolls in the rumen to take up a planar configuration which is retained in the rumen. The sheet may be placed within a plastics netting envelope to give more controlled erosion and release of medicament.

Inventors

  • 👤 Gerald J. L. Griffin
  • 👤 Malcolm D. Brewer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 19:13
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0068; A61D; A61D7/00; A61M; A61M31/00; A61M31/002

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 96 words
A device for administration of a veterinary medicament to a ruminant comprising a first resilient sheet of an erodable ethylene-vinyl acetate copolymer in which said medicament is uniformly dispersed and a second resilient, support sheet of a water insoluble polymer, said second sheet being at least dimensionally coextensive with said first sheet and to which said first sheet is attached, said device being of a size and composition such that it is capable of constraint in a rolled-up configuration permitting oral administration and of a subsequent assumption of an unrolled configuration when unconstrained in the rumen.
Claim 2
Independent Claim 96 words
A device for administration of a veterinary medicament to a ruminant comprising a first resilient sheet of an erodable ethylene-vinyl acetate copolymer in which said medicament is uniformly dispersed and a second resilient, support sheet of a water insoluble polymer, said second sheet being at least dimensionally coextensive with said first sheet and to which said first sheet is attached, said device being of a size and composition such that it is capable of constraint in a rolled-up configuration permitting oral administration and of a subsequent assumption of an unrolled configuration when unconstrained in the rumen.
Claim 3
Dependent Claim 19 words
A device according to claim 1 wherein the medicament constitutes 15 to 40% by weight of said first sheet.
Claim 4
Dependent Claim 12 words
A device according to claim 2 wherein the medicament is an anthelmintic.
Claim 5
Dependent Claim 16 words
A device according to claim 2 wherein said second support sheet consists of ethylene-vinyl acetate copolymer.

References Cited (Backward Citations)

US3844285A Cited
US3625214A Cited
US3832252A Cited
US3903880A Cited
US4029757A Cited
US4031200A Cited
US4072551A Cited
US4055178A Cited
US4228149A Cited
US4180558A Cited
US4268497A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-12-28 1985-06-29 1985-12-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-12-28 1989-06-29 1989-12-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-12-28 1993-06-29 1993-12-29 $7700.00 Window Closed / Lapsed

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