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US4243776A
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Preparation of non-thrombogenic polymeric material article with platelet anti-aggregative agent
Assignee: Anic SpA
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Filing: 1978-06-21
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Granted: 1981-01-06
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Expires: 1998-06-21
Abstract
Abstract Biocompatible articles are obtained by treating a polymeric material with a hydrolyzing agent on its surface and covalently binding thereon a biological agent, such as an anti-platelet-aggregation agent.
Inventors
- 👤 Walter Marconi
- 👤 Francesco Pittalis
- 👤 Francesco Bartoli
- 👤 Franco Morisi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 08:23
CPC Classifications
C; C08; C08G; C08G85/00; A; A61; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/59; A61K47/595; A61L; A61L27/00; A61L27/14; A61L27/18; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0041; A61L33/06; A61L33/062; C08B; C08B15/00; C08B15/05; C08B15/06; C08G18/00; C08G18/06; C08G18/28; C08G18/30; C08G18/38; C08G18/3819; C08G18/3842; C08G18/3844
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
38 words
A method for rendering an article made from a polymeric material non-thrombogenic comprising chemically binding a platelet anti-aggregative agent selected from the group consisting of 4,5-diphenyl-2-bis-(2-hydroxyethyl)amino oxazole and 4,8-dipiperidino-2,6-diethanolamino-pyrimido-5, 4-d pyrimidine to the surface of said polymeric material.
Claim 2
Independent Claim
38 words
A method for rendering an article made from a polymeric material non-thrombogenic comprising chemically binding a platelet anti-aggregative agent selected from the group consisting of 4,5-diphenyl-2-bis-(2-hydroxyethyl)amino oxazole and 4,8-dipiperidino-2,6-diethanolamino-pyrimido-5, 4-d pyrimidine to the surface of said polymeric material.
Claim 3
Dependent Claim
24 words
The method as defined in claim 1 wherein said polymeric material is selected from the group consisting of nylon polyamides, cellulose polymers, and polyacrylates.
Claim 4
Dependent Claim
35 words
A method as defined in claim 1 wherein the platelet anti-aggregative agent is chemically bound to the polymeric material by contacting a polymeric material that has been subjected to hydrolysis with the platelet aggregative agent.
Claim 5
Dependent Claim
23 words
A method as defined in claim 1 wherein the polymer is a nylon polyamide and the platelet anti-aggregative agent is 4,5-diphenyl-2-bis-(2-hydroxyethyl) amino oxazole.
Claim 6
Dependent Claim
15 words
A biocompatible sound, tube, membrane or artificial organ made by the process of claim 1.
Claim 7
Dependent Claim
15 words
A biocompatible sound, tube, membrane or artificial organ made by the process of claim 4.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-01-06 | 1984-07-07 | 1985-01-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-01-06 | 1988-07-07 | 1989-01-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-01-06 | 1992-07-07 | 1993-01-06 | $7700.00 | Window Closed / Lapsed |