Patent US3963685A successfully refreshed from Google Patents.
US3963685A
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US
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Alcohol soluble hydrophilic polymer via aqueous polymerization
Assignee: Individual
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Filing: 1974-05-13
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Granted: 1976-06-15
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Expires: 1994-05-13
Abstract
Abstract Hydrophilic, water insoluble, organic solvent soluble polymers of hydroxyalkyl methacrylate or acrylate of high purity are prepared in water using hydroxyalkyl methacrylate or acrylate monomer having not over 0.035 weight percent of alkylene glycol dimethacrylate or diacrylate. The polymers have high molecular weight and narrow molecular weight distribution and are useful for medical applications, e.g., as a burn dressing.
Inventors
- 👤 Robert A. Abrahams
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:10
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/74; A61K31/765; A61K31/78; A61K47/00; A61K47/30; A61K47/32; A61L; A61L26/00; A61L26/0061; A61L26/008; C; C08; C08F; C08F20/00; C08F20/02; C08F20/10; C08F20/26; C08F20/28; C08F220/00; C08F220/02; C08F220/10; C08F220/26; C08F220/28; C08F220/281; C08L; C08L33/00; C08L33/04; C08L33/14; Y; Y10; Y10S; Y10S526/00; Y10S526/93; Y10S526/936
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
153 words
A process for preparing a solid waterinsoluble, methanol-soluble hydrophilic polymer which consists essentially of polymerizing in water, monomers consisting essentially of (a) a monomer of the formula ##EQU4## where R is an alkylene group of 2 to 3 carbon atoms, and wherein R' is hydrogen or methyl; with not more than 0.035 weight percent, based on the weight of said monomer of formula (1), of a diester of the formula ##EQU5## wherein R and R' have the above meanings or (b) said monomers of formula (1) and formula (2) together with a third monomer in an amount as high as 10%, said third monomer being methacrylic acid or ##EQU6## initiating polymerization by irradiation or a free radical initiator employing a ratio of total monomer to water from 10:90 to 70:30, conducting the polymerization for a period of time sufficient to produce said polymer, and recovering said polymer from the resulting reaction product mixture.
Claim 2
Dependent Claim
153 words
A process for preparing a solid waterinsoluble, methanol-soluble hydrophilic polymer which consists essentially of polymerizing in water, monomers consisting essentially of (a) a monomer of the formula ##EQU4## where R is an alkylene group of 2 to 3 carbon atoms, and wherein R' is hydrogen or methyl; with not more than 0.035 weight percent, based on the weight of said monomer of formula (1), of a diester of the formula ##EQU5## wherein R and R' have the above meanings or (b) said monomers of formula (1) and formula (2) together with a third monomer in an amount as high as 10%, said third monomer being methacrylic acid or ##EQU6## initiating polymerization by irradiation or a free radical initiator employing a ratio of total monomer to water from 10:90 to 70:30, conducting the polymerization for a period of time sufficient to produce said polymer, and recovering said polymer from the resulting reaction product mixture.
Claim 3
Dependent Claim
18 words
A process according to claim 1 wherein said monomers are (b), R is ethylene and R' is methyl.
Claim 4
Dependent Claim
17 words
A process according to claim 2 wherein there is present in the monomers 10% of methacrylic acid.
Claim 5
Dependent Claim
16 words
A process according to claim 2 where there is present in the monomers 10% of ##EQU7##
Claim 6
Dependent Claim
11 words
A process according to claim 1 wherein said monomers are (a).
Claim 7
Dependent Claim
14 words
A process according to claim 5 wherein the polymerization is initiated with isopropyl percarbonate.
Claim 8
Dependent Claim
16 words
A process according to claim 5 wherein a free radical initiator is included in the composition.
Claim 9
Dependent Claim
22 words
A process according to claim 7 wherein said monomer (1) is 2-hydroxyethyl methacrylate and wherein said diester (2) is ethylene glycol dimethacrylate.
Claim 10
Dependent Claim
15 words
A process according to claim 8 wherein the amount of diester is 0.02 to 0.035%.
Claim 11
Dependent Claim
15 words
A process according to claim 9 wherein the amount of diester is 0.02 to 0.03%.
Claim 12
Dependent Claim
15 words
A process according to claim 10 wherein the amount of diester is 0.02 to 0.025%.
Claim 13
Dependent Claim
15 words
A process according to claim 1 wherein the amount of diester is 0.02 to 0.035%.
Claim 14
Dependent Claim
21 words
A process according to claim 5 wherein said monomer (1) is 2-hydroxyethyl methacrylate and wherein said diester is ethylene glycol dimethacrylate.
Claim 15
Dependent Claim
36 words
A process according to claim 13, wherein a free radical initiator is included in the composition in an amount sufficient to produce a polymer having a molecular weight above about 250,000 by intrinsic viscosity in methoxyethane.
Claim 16
Dependent Claim
15 words
A process according to claim 13 including washing the polymer to a purity above 99.5%.
Claim 17
Dependent Claim
16 words
A process according to claim 13 wherein the ratio of 2-hydroxyethyl methacrylate to water is 35:65.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-15 | 1979-12-15 | 1980-06-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-15 | 1983-12-15 | 1984-06-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-15 | 1987-12-15 | 1988-06-15 | $7700.00 | Window Closed / Lapsed |