Patent EP0409351A1 successfully refreshed from Google Patents.
EP0409351A1
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Contrast medium composition
Assignee: GE Healthcare AS
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Filing: 1990-07-19
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Granted: —
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Expires: 2010-07-19
Abstract
Abstract There is provided a contrast medium composition comprising magnetically responsive particles and a physiologically tolerable, incompletely hydrated viscosity enhancing agent.
Inventors
- 👤 Helge Guttorm Gundersen
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 13:27
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/06; A61K49/18; A61K49/1818; A61K49/1887; A61K49/1803; A61K49/1821; A61K49/1824; A61K49/1827; A61K49/1851; A61K49/1857
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
17 words
A contrast medium composition comprising magnetically responsive particles and a physiologically tolerable, incompletely hydrated, viscosity enhancing agent.
Claim 2
Dependent Claim
17 words
A contrast medium composition comprising magnetically responsive particles and a physiologically tolerable, incompletely hydrated, viscosity enhancing agent.
Claim 3
Dependent Claim
10 words
A composition as claimed in claim 1 in pulverulent form.
Claim 4
Dependent Claim
23 words
A composition as claimed in either of claims 1 and 2 comprising a said viscosity enhancing agent provided with a delayed release coating.
Claim 5
Dependent Claim
21 words
A composition as claimed in claim 3 comprising a said viscosity enhancing agent provided with a gastric fluid-resistant delayed release coating.
Claim 6
Dependent Claim
18 words
A composition as claimed in any of claims 1 to 4, wherein said viscosity enhancing agent is non-biodegradable.
Claim 7
Dependent Claim
31 words
A composition as claimed in any of claims 1 to 5, wherein said viscosity enhancing agent is water-soluble, water-swellable, or is a bulking agent, or comprises a mixture of such materials.
Claim 8
Dependent Claim
28 words
A composition as claimed in any of claims 1 to 6, capable on hydration of said viscosity enhancing agent of achieving a viscosity of 200 to 5000 cps.
Claim 9
Dependent Claim
28 words
A composition as claimed in any of claims 1 to 7, capable on contacting an aqueous medium of achieving a maximum viscosity within 15 seconds to 60 minutes.
Claim 10
Dependent Claim
27 words
A composition as claimed in any of claims 1 to 8, capable on contacting an aqueous medium of achieving a maximum viscosity after at least 2 minutes.
Claim 11
Dependent Claim
25 words
A composition as claimed in any of claims 1 to 9, wherein said viscosity enhancing agent constitutes 1 to 99.5% by weight of the composition.
Claim 12
Dependent Claim
21 words
A composition as claimed in any of claims 1 to 10, wherein said magnetically responsive particles are ferromagnetic, ferrimagnetic or superparamagnetic.
Claim 13
Dependent Claim
31 words
A composition as claimed in any of claims 1 to 11, wherein said magnetically responsive particles are selected from particles of magnetite, gamma ferric oxide, and cobalt, nickel and manganese ferrites.
Claim 14
Dependent Claim
20 words
A composition as claimed in any of claims 1 to 12 dispersed or suspended in a physiologically tolerable carrier fluid.
Claim 15
Dependent Claim
31 words
The use of a physiologically tolerable viscosity enhancing agent for the manufacture of a composition as claimed in any one of claims 1 to 13 for use in magnetic resonance imaging.
Claim 16
Dependent Claim
28 words
The use of magnetically responsive particles for the manufacture of a composition as claimed in any one of claims 1 to 13 for use in magnetic resonance imaging.
Claim 17
Independent Claim
64 words
A method of generating a magnetic resonance image of a human or non-human animal body, said method comprising administering to an externally voided body cavity of said body a composition as claimed in any one of claims 1 to 13, optionally after dispersion thereof in a physiologically tolerable aqueous medium, and generating a magnetic resonance image of at least a part of said body.
Claim 18
Dependent Claim
25 words
A diagnostic contrast agent kit comprising a plurality of magnetically responsive particles and, packaged separately thereto, a physiologically tolerable viscosity enhancement agent in pulverulent form
Claim 19
Dependent Claim
25 words
A diagnostic contrast agent kit comprising a plurality of magnetically responsive particles and, packaged separately thereto, a physiologically tolerable viscosity enhancement agent in pulverulent form
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