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WO1993021971A1
Expired / Lapsed
WO
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Fibrin coated polymer surfaces
Assignee: McMaster University
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Filing: 1993-04-16
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Granted: —
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Expires: 2013-04-16
Abstract
Abstract Surfaces of polymeric materials are coated with a layer of thermally denatured fibrinogen. The fibrinogen may be treated with thrombin to produce fibrin, and additional fibrinogen and factor XIII added to produce a cross-linked fibrin coating. The resulting coated surface is stable, anti-thrombotic and resistant to platelet adhesion. Polymeric materials coated in this way are useful in constructing vascular grafts and prosthetic devices, and provide test systems useful in the study of thrombogenesis.
Inventors
- 👤 Fraser D. Rubens
- 👤 Paul Douglas Bishop
Bibliographic Details
Application Number
—
Jurisdiction
WO
Data Source
google_patents
Last Synchronized
2026-10-23 05:18
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/06; A61L33/12; A61L33/126; A61L27/00; A61L27/28; A61L27/34; Y; Y10; Y10T; Y10T436/00; Y10T436/10
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References Cited (Backward Citations)
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