Patent US1914293A successfully refreshed from Google Patents.
Patent US7335192B2 successfully refreshed from Google Patents.
US7335192B2
Expired / Lapsed
US
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Apparatus and methods for treating congestive heart disease
Assignee: Angiodynamics Inc
•
Filing: 2003-05-13
•
Granted: 2008-02-26
•
Expires: 2023-05-13
Abstract
Abstract Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a "once-through" fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.
Inventors
- 👤 Gad Keren
- 👤 Ascher Shmulewitz
- 👤 Benjamin Spenser
- 👤 Michael Arad
- 👤 Randy J Kesten
- 👤 Sophia Pesotchinsky
- 👤 Michael H. Rosenthal
- 👤 Andrew W. Kramer
- 👤 Sam G. Payne
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:48
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12131; A61B17/12181; A61B17/1219; A61B17/12027; A61B17/12036; A61B17/1204; A61B17/12045; A61B17/12099; A61B17/12109; A61B17/12136; A61M; A61M1/00; A61M1/36; A61M1/3613; A61M1/3621; A61M1/3653; A61M1/3659; A61M25/00; A61M25/10; A61M27/00; A61M27/002; A61M60/00; A61M60/10; A61M60/104; A61M60/109; A61M60/113; A61M60/122; A61M60/126; A61M60/13; A61M60/20; A61M60/205; A61M60/216; A61M60/226; A61M60/232; A61M60/247; A61M60/253; A61M60/258; A61M60/268; A61M60/279; A61M60/30; A61M60/31; A61M60/33; A61M60/36; A61M60/38; A61M60/80; A61M60/802; A61M60/833; A61M60/855; A61M60/865; A61M60/867; A61B17/12009; A61B17/12013; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/00831; A61B2017/00898; A61B17/04; A61B17/06; A61B17/06066; A61B2017/061; A61B17/22; A61B2017/22051; A61B2017/22054; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2002/068; A61M1/3623; A61M2025/1043; A61M2025/1052; A61M2210/00; A61M2210/10; A61M2210/1078; A61M2210/1082; A61M2210/12; A61M2210/125; A61M25/0067; A61M25/0074; A61M25/0075; A61M25/1011; A61M60/148; A61M60/40; A61M60/403; A61M60/408; A61M60/411; A61M60/414
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
144 words
A method for enhancing renal function in a body of a patient, comprising: locally delivering a volume of fluid agent from a source located externally of the patient's body and substantially only into a plurality of renal arteries having respective ostia at unique respective locations along an abdominal aorta wall of an abdominal aorta in the body; positioning an expandable member within the abdominal aorta below the plurality of renal arteries, thereby inhibiting blood from flowing between the expandable member and the abdominal aorta wall while allowing blood to flow from an aorta into the plurality of renal arteries and while supplying blood to the lower extremities via a blood pass through lumen; wherein the volume of fluid agent is delivered into the plurality of renal arteries substantially simultaneously; and wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 2
Independent Claim
144 words
A method for enhancing renal function in a body of a patient, comprising: locally delivering a volume of fluid agent from a source located externally of the patient's body and substantially only into a plurality of renal arteries having respective ostia at unique respective locations along an abdominal aorta wall of an abdominal aorta in the body; positioning an expandable member within the abdominal aorta below the plurality of renal arteries, thereby inhibiting blood from flowing between the expandable member and the abdominal aorta wall while allowing blood to flow from an aorta into the plurality of renal arteries and while supplying blood to the lower extremities via a blood pass through lumen; wherein the volume of fluid agent is delivered into the plurality of renal arteries substantially simultaneously; and wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 3
Dependent Claim
34 words
The method of claim 1 , wherein the local delivery of fluid agent into the plurality of renal arteries comprises: locally delivering a volume of diuretic fluid agent into the plurality of renal arteries.
Claim 4
Dependent Claim
33 words
The method of claim 2 , wherein the local delivery of diuretic fluid agent into the plurality of renal arteries comprises: locally delivering a volume of furosemide into the plurality of renal arteries.
Claim 5
Dependent Claim
33 words
The method of claim 2 , wherein the local delivery of diuretic fluid agent into the plurality of renal arteries comprises: locally delivering a volume of thiazide into the plurality of renal arteries.
Claim 6
Dependent Claim
73 words
The method of claim 1 , further comprising: providing a catheter with a proximal end portion and a distal end portion; providing a source of fluid agent; coupling the proximal end portion of the catheter to the source of fluid agent externally of the patient's body; using the catheter to locally deliver the volume of the fluid agent from the source externally of the patient's body and into the plurality of renal arteries.
Claim 7
Dependent Claim
42 words
The method of claim 5 , wherein the local delivery of fluid agent into the plurality of renal arteries further comprises: injecting the volume of fluid agent through a delivery port of the catheter located within an abdominal aorta of the patient.
Claim 8
Dependent Claim
32 words
The method of claim 1 , wherein the local delivery of fluid agent into the plurality of renal arteries comprises: locally delivering a volume of vasopressor into the plurality of renal arteries.
Claim 9
Dependent Claim
32 words
The method of claim 7 , wherein the local delivery of vasopressor into the plurality of renal arteries further comprises: locally delivering a volume of Dopamine into the plurality of renal arteries.
Claim 10
Dependent Claim
32 words
The method of claim 1 , wherein the local delivery of fluid agent into the plurality of renal arteries comprises: locally delivering a volume of vasodilator into the plurality of renal arteries.
Claim 11
Dependent Claim
32 words
The method of claim 1 , further comprising: allowing aortic blood to flow downstream across the location and into downstream circulation while delivering the fluid agent into the plurality of renal arteries.
Claim 12
Independent Claim
157 words
A method for enhancing renal function in a body of a patient, comprising: inserting a catheter having a drug delivery lumen through an iliac artery and into an abdominal aorta, the catheter comprising a discharge port in fluid communication with the drug delivery lumen; positioning an expandable member in the abdominal aorta, below a plurality of renal arteries; expanding the expandable member so as to inhibit blood from flowing between the expandable member and a wall of the abdominal aorta while allowing blood to flow from an aorta into the plurality of renal arteries and while supplying blood to the lower extremities via a blood pass through lumen; delivering a volume of fluid agent through the drug delivery lumen and out of the discharge port to a location in the abdominal aorta above the expandable member, adjacent to the plurality of renal arteries; wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 13
Independent Claim
157 words
A method for enhancing renal function in a body of a patient, comprising: inserting a catheter having a drug delivery lumen through an iliac artery and into an abdominal aorta, the catheter comprising a discharge port in fluid communication with the drug delivery lumen; positioning an expandable member in the abdominal aorta, below a plurality of renal arteries; expanding the expandable member so as to inhibit blood from flowing between the expandable member and a wall of the abdominal aorta while allowing blood to flow from an aorta into the plurality of renal arteries and while supplying blood to the lower extremities via a blood pass through lumen; delivering a volume of fluid agent through the drug delivery lumen and out of the discharge port to a location in the abdominal aorta above the expandable member, adjacent to the plurality of renal arteries; wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 14
Dependent Claim
48 words
The method of claim 11 , further comprising synchronizing the steps of expanding the expandable member and delivering the volume of fluid agent such that there is a time lag T 1 between the beginning of the expandable member expansion and the beginning of the fluid agent delivery.
Claim 15
Dependent Claim
53 words
The method of claim 12 , further comprising contracting the expandable member, and synchronizing the steps of contracting the expandable member and delivering the volume of fluid agent such that there is a time lag T 2 between the end of the fluid agent delivery and the end of the expandable member contraction.
Claim 16
Dependent Claim
15 words
The method of claim 13 , comprising controlling the synchronization steps via an autocontrol device.
Claim 17
Dependent Claim
27 words
The method of claim 13 , wherein the synchronization steps are automated so as to control a level of fluid agent in the plurality of renal arteries.
Claim 18
Independent Claim
270 words
A method for enhancing renal function in a body of a patient, comprising: inserting an elongated catheter shaft through an iliac artery and into an abdominal aorta, the elongated catheter shaft comprising a first end portion disposed toward a proximal end of the shaft, a second end portion disposed toward a distal end of the shaft, an inflation lumen, a drug delivery lumen, a blood pass through lumen, and an expandable member, wherein the second end portion comprises a discharge port in fluid communication with the drug delivery lumen, the expandable member is in fluid communication with the inflation lumen, and the blood pass through lumen comprises an inlet port disposed distal to the expandable member and an outlet port disposed proximal to the expandable member; positioning the expandable member in the abdominal aorta, below a plurality of renal arteries; delivering an inflation fluid from an inflation source through the inflation lumen to the expandable member, thereby expanding the expandable member so as to inhibit blood from flowing across a junction formed by the expandable member and the abdominal aorta, while allowing blood to flow from an aorta into the plurality of renal arteries, and while allowing blood to flow into the inlet port through the blood pass through lumen and out of the outlet port; delivering an amount of a drug from a drug delivery source through the drug delivery lumen and out of the discharge port to a location in the abdominal aorta above the expandable member, adjacent to the plurality of renal arteries; wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 19
Independent Claim
270 words
A method for enhancing renal function in a body of a patient, comprising: inserting an elongated catheter shaft through an iliac artery and into an abdominal aorta, the elongated catheter shaft comprising a first end portion disposed toward a proximal end of the shaft, a second end portion disposed toward a distal end of the shaft, an inflation lumen, a drug delivery lumen, a blood pass through lumen, and an expandable member, wherein the second end portion comprises a discharge port in fluid communication with the drug delivery lumen, the expandable member is in fluid communication with the inflation lumen, and the blood pass through lumen comprises an inlet port disposed distal to the expandable member and an outlet port disposed proximal to the expandable member; positioning the expandable member in the abdominal aorta, below a plurality of renal arteries; delivering an inflation fluid from an inflation source through the inflation lumen to the expandable member, thereby expanding the expandable member so as to inhibit blood from flowing across a junction formed by the expandable member and the abdominal aorta, while allowing blood to flow from an aorta into the plurality of renal arteries, and while allowing blood to flow into the inlet port through the blood pass through lumen and out of the outlet port; delivering an amount of a drug from a drug delivery source through the drug delivery lumen and out of the discharge port to a location in the abdominal aorta above the expandable member, adjacent to the plurality of renal arteries; wherein the volume of fluid agent being delivered is adapted to enhance renal function.
Claim 20
Dependent Claim
48 words
The method of claim 16 , further comprising synchronizing the steps of expanding the expandable member and delivering the amount of the drug such that there is a time lag T 1 between the beginning of the expandable member expansion and the beginning of the fluid agent delivery.
Claim 21
Dependent Claim
52 words
The method of claim 17 , further comprising contracting the expandable member, and synchronizing the steps of contracting the expandable member and delivering the amount of the drug such that there is a time lag T 2 between the end of the drug delivery and the end of the expandable member contraction.
Claim 22
Dependent Claim
15 words
The method of claim 18 , comprising controlling the synchronization steps via an autocontrol device.
Claim 23
Dependent Claim
27 words
The method of claim 18 , wherein the synchronization steps are automated so as to control a level of fluid agent in the plurality of renal arteries.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2011-02-25 | 2011-08-27 | 2012-02-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2015-02-25 | 2015-08-27 | 2016-02-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2019-02-25 | 2019-08-27 | 2020-02-26 | $7700.00 | Window Closed / Lapsed |