Patent US2427850A successfully refreshed from Google Patents.
US6746485B1
Expired / Lapsed
US
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Hair used as a biologic disk, replacement, and/or structure and method
Assignee: Medtronic Europe SARL
•
Filing: 2000-02-16
•
Granted: 2004-06-08
•
Expires: 2020-02-16
Abstract
Abstract Hair is used as a biologic disk, replacement, and/or structure.
Inventors
- 👤 James F. Zucherman
- 👤 Ken Y. Hsu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:04
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3683; A61L27/3687; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/44; A61F2/441; A61F2/442; A61L27/3604; A61L27/3641; A61L27/3645; A61L27/3654; A61L27/3658; A61F2/08; A61F2/3094; A61F2/30965; A61F2/28; A61F2002/2817; A61F2002/30001; A61F2002/30316; A61F2002/30535; A61F2002/30581; A61F2002/30583; A61F2002/444; A61F2002/4495; A61F2210/00; A61F2210/0085; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61F2310/00179; A61F2310/00293; A61F2310/00365; A61L2430/00; A61L2430/38
Claims Analysis
Total Claims: 103
Claim 1
Independent Claim
25 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with keratin sulfate placed in the sack.
Claim 2
Dependent Claim
25 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with keratin sulfate placed in the sack.
Claim 3
Dependent Claim
26 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with a hydrophilic gel placed in the sack.
Claim 4
Dependent Claim
26 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with a hydrophilic gel placed in the sack.
Claim 5
Dependent Claim
40 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with the sack at least partially surrounding at least one of a hydrogel, a hydrophilic gel, keratin sulfate, and a growth factor.
Claim 6
Dependent Claim
40 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with the sack at least partially surrounding at least one of a hydrogel, a hydrophilic gel, keratin sulfate, and a growth factor.
Claim 7
Dependent Claim
29 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with the sack at least partially surrounding a cartilage growth factor.
Claim 8
Dependent Claim
29 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with the sack at least partially surrounding a cartilage growth factor.
Claim 9
Dependent Claim
30 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with at least some of which has been processed as keratin sulfate.
Claim 10
Dependent Claim
30 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack with at least some of which has been processed as keratin sulfate.
Claim 11
Dependent Claim
29 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein a cartilage growth factor is applied to said hair.
Claim 12
Dependent Claim
29 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein a cartilage growth factor is applied to said hair.
Claim 13
Dependent Claim
26 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein BMP is applied to said hair.
Claim 14
Dependent Claim
26 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein BMP is applied to said hair.
Claim 15
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein one or more morphogenetic growth factors is applied to said hair.
Claim 16
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein one or more morphogenetic growth factors is applied to said hair.
Claim 17
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein one or more recombinant growth factors is applied to said hair.
Claim 18
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein one or more recombinant growth factors is applied to said hair.
Claim 19
Dependent Claim
88 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; wherein an outer surface of the sack is covered with a polymer material; and wherein said polymer material can include at least one of the group consisting of polypropylene, polylactic acid materials, polyesther polymer mesh, composites of collagen and BMP, titanium fiber with BMP with or without non-collagenase proteins, polydioxanone, polyphosphazenes and BMP, ceramic collagen composite, expanded polytetrafluoroethylene barrier membranes, and ethylene-vinyl acetate copolymers in methylene chloride (Elvax 40 ).
Claim 20
Dependent Claim
88 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; wherein an outer surface of the sack is covered with a polymer material; and wherein said polymer material can include at least one of the group consisting of polypropylene, polylactic acid materials, polyesther polymer mesh, composites of collagen and BMP, titanium fiber with BMP with or without non-collagenase proteins, polydioxanone, polyphosphazenes and BMP, ceramic collagen composite, expanded polytetrafluoroethylene barrier membranes, and ethylene-vinyl acetate copolymers in methylene chloride (Elvax 40 ).
Claim 21
Dependent Claim
43 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 22
Dependent Claim
43 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 23
Dependent Claim
47 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; and wherein the replacement is comprised of said hair formed into a sack; and wherein said sack is filled with a material which has a state dependent upon the temperature of the material.
Claim 24
Dependent Claim
47 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; and wherein the replacement is comprised of said hair formed into a sack; and wherein said sack is filled with a material which has a state dependent upon the temperature of the material.
Claim 25
Dependent Claim
9 words
The replacement of claim 12 comprised of human hair.
Claim 26
Dependent Claim
9 words
The replacement of claim 12 comprised of woven hair.
Claim 27
Dependent Claim
9 words
The replacement of claim 12 comprised of matted hair.
Claim 28
Dependent Claim
14 words
The replacement of claim 12 wherein said hair is formed into a replacement annulus.
Claim 29
Dependent Claim
16 words
The replacement of claim 12 wherein said hair is used to construct in a replacement annulus.
Claim 30
Dependent Claim
16 words
The replacement of claim 12 wherein said hair is one of autologous hair and homologous hair.
Claim 31
Dependent Claim
16 words
The replacement of claim 12 wherein said hair is one of autogeneic hair and allogeneic hair.
Claim 32
Dependent Claim
16 words
The replacement of claim 12 wherein said sack at least partially surrounds a cartilage growth factor.
Claim 33
Dependent Claim
16 words
The replacement of claim 12 wherein said sack surrounds hair treated to model a natural disk.
Claim 34
Dependent Claim
18 words
The replacement of claim 12 wherein the replacement is comprised of at least two layers of said hair.
Claim 35
Dependent Claim
26 words
The replacement of claim 12 wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair.
Claim 36
Dependent Claim
23 words
The replacement of claim 23 wherein the hair in the first layer has a different orientation than the hair in the second layer.
Claim 37
Dependent Claim
15 words
The replacement of claim 12 wherein a cartilage growth factor is applied to said hair.
Claim 38
Dependent Claim
12 words
The replacement of claim 12 wherein BMP is applied to said hair.
Claim 39
Dependent Claim
17 words
The replacement of claim 12 wherein one or more morphogenetic growth factors is applied to said hair.
Claim 40
Dependent Claim
17 words
The replacement of claim 12 wherein one or more recombinant growth factors is applied to said hair.
Claim 41
Dependent Claim
17 words
The replacement of claim 12 wherein outer surface of the sack is covered with a polymer material.
Claim 42
Dependent Claim
61 words
The replacement of claim 29 wherein said polymer material can include at least one of the group consisting of polypropylene, polylactic acid materials, polyesther polymer mesh, composites of collagen and BMP, titanium fiber with BMP with or without non-collagenase proteins, polydioxanone, polyphosphazenes and BMP, ceramic collagen composite, expanded polytetrafluoroethylene barrier membranes, and ethylene-vinyl acetate copolymers in methylene chloride (Elvax 40 ).
Claim 43
Dependent Claim
29 words
The replacement of claim 12 wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 44
Dependent Claim
29 words
The replacement of claim 12 wherein said hair is woven and/or blended together using at least one of the following techniques consisting of: matting, denaturation, acid treatment, and weaving.
Claim 45
Dependent Claim
17 words
The replacement of claim 12 wherein said hair is treated with one or more bone growth factors.
Claim 46
Dependent Claim
19 words
The replacement of claim 12 comprised of hair at least some of which has been processed as keratin sulfate.
Claim 47
Dependent Claim
16 words
The replacement of claim 12 wherein said sack contains one or more bone growth factor materials.
Claim 48
Dependent Claim
59 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; and wherein the replacement is comprised of said hair formed into a sack; and wherein said sack is filled with a material; and wherein said material becomes at least one of more viscous and resilient when the material reaches the temperature of a patient's body.
Claim 49
Dependent Claim
59 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; and wherein the replacement is comprised of said hair formed into a sack; and wherein said sack is filled with a material; and wherein said material becomes at least one of more viscous and resilient when the material reaches the temperature of a patient's body.
Claim 50
Dependent Claim
9 words
The replacement of claim 36 comprised of human hair.
Claim 51
Dependent Claim
9 words
The replacement of claim 36 comprised of woven hair.
Claim 52
Dependent Claim
9 words
The replacement of claim 36 comprised of matted hair.
Claim 53
Dependent Claim
14 words
The replacement of claim 36 wherein said hair is formed into a replacement annulus.
Claim 54
Dependent Claim
16 words
The replacement of claim 36 wherein said hair is used to construct in a replacement annulus.
Claim 55
Dependent Claim
16 words
The replacement of claim 36 wherein said hair is one of autologous hair and homologous hair.
Claim 56
Dependent Claim
16 words
The replacement of claim 36 wherein said hair is one of autogeneic hair and allogeneic hair.
Claim 57
Dependent Claim
16 words
The replacement of claim 36 wherein said sack at least partially surrounds a cartilage growth factor.
Claim 58
Dependent Claim
20 words
The replacement of claim 36 comprised of hair in the center of the sack treated to model a natural disk.
Claim 59
Dependent Claim
18 words
The replacement of claim 36 wherein the sack is comprised of at least two layers of said hair.
Claim 60
Dependent Claim
26 words
The replacement of claim 36 wherein the sack is comprised of at least a first layer of woven hair and a second layer of woven hair.
Claim 61
Dependent Claim
23 words
The replacement of claim 47 wherein the hair in the first layer has a different orientation than the hair in the second layer.
Claim 62
Dependent Claim
15 words
The replacement of claim 36 wherein a cartilage growth factor is applied to said hair.
Claim 63
Dependent Claim
12 words
The replacement of claim 36 wherein BMP is applied to said hair.
Claim 64
Dependent Claim
17 words
The replacement of claim 36 wherein one or more morphogenetic growth factors is applied to said hair.
Claim 65
Dependent Claim
17 words
The replacement of claim 36 wherein one or more recombinant growth factors is applied to said hair.
Claim 66
Dependent Claim
18 words
The replacement of claim 36 wherein an outer surface of the sack is covered with a polymer material.
Claim 67
Dependent Claim
61 words
The replacement of claim 53 wherein said polymer material can include at least one of the group consisting of polypropylene, polylactic acid materials, polyesther polymer mesh, composites of collagen and BMP, titanium fiber with BMP with or without non-collagenase proteins, polydioxanone, polyphosphazenes and BMP, ceramic collagen composite, expanded polytetrafluoroethylene barrier membranes, and ethylene-vinyl acetate copolymers in methylene chloride (Elvax 40 ).
Claim 68
Dependent Claim
29 words
The replacement of claim 36 wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 69
Dependent Claim
29 words
The replacement of claim 36 wherein said hair is woven and/or blended together using at least one of the following techniques consisting of: matting, denaturation, acid treatment, and weaving.
Claim 70
Dependent Claim
17 words
The replacement of claim 36 wherein said hair is treated with one or more bone growth factors.
Claim 71
Dependent Claim
19 words
The replacement of claim 36 comprised of hair at least some of which has been processed as keratin sulfate.
Claim 72
Dependent Claim
16 words
The replacement of claim 36 wherein said sack contains one or more bone growth factor materials.
Claim 73
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said hair is treated with one or more bone growth factors.
Claim 74
Dependent Claim
31 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said hair is treated with one or more bone growth factors.
Claim 75
Dependent Claim
32 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said sack is filled with one or more bone growth factor materials.
Claim 76
Dependent Claim
32 words
A replacement for at least part of a vertebral disk, the replacement comprising hair formed into a sack; and wherein said sack is filled with one or more bone growth factor materials.
Claim 77
Independent Claim
50 words
A method of delivering a disk prosthetic device to an intervertebral space comprising the steps of: first delivering a disk prosthetic device comprised in part of hair to the intervertebral space said disk prosthetic device formed into a sack; and second delivering a filling material to the disk prosthetic device.
Claim 78
Independent Claim
50 words
A method of delivering a disk prosthetic device to an intervertebral space comprising the steps of: first delivering a disk prosthetic device comprised in part of hair to the intervertebral space said disk prosthetic device formed into a sack; and second delivering a filling material to the disk prosthetic device.
Claim 79
Dependent Claim
68 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair formed into a sack with keratin sulfate placed in the sack.
Claim 80
Dependent Claim
68 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair formed into a sack with keratin sulfate placed in the sack.
Claim 81
Dependent Claim
70 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair is formed into a sack with a hydrophillic gel placed in the sack.
Claim 82
Dependent Claim
70 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair is formed into a sack with a hydrophillic gel placed in the sack.
Claim 83
Dependent Claim
73 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein said hair in the first layer has a different orientation than said hair in the second layer; and wherein said hair is formed into a structure with the structure at least partially surrounding a cartilage growth factor.
Claim 84
Dependent Claim
73 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein said hair in the first layer has a different orientation than said hair in the second layer; and wherein said hair is formed into a structure with the structure at least partially surrounding a cartilage growth factor.
Claim 85
Dependent Claim
68 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair at least some of which has been processed at keratin sulfate.
Claim 86
Dependent Claim
68 words
A replacement for at least part of a vertebral disk, the replacement comprising hair; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein the hair at least some of which has been processed at keratin sulfate.
Claim 87
Dependent Claim
60 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein a cartilage growth factor is applied to said hair.
Claim 88
Dependent Claim
60 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein a cartilage growth factor is applied to said hair.
Claim 89
Dependent Claim
57 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein BMP is applied to said hair.
Claim 90
Dependent Claim
57 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein BMP is applied to said hair.
Claim 91
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein one or more morphogenetic growth factors is applied to said hair.
Claim 92
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein one or more morphogenetic growth factors is applied to said hair.
Claim 93
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein one or more recombinant growth factors is applied to said hair.
Claim 94
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein one or more recombinant growth factors is applied to said hair.
Claim 95
Dependent Claim
71 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is formed into a sack and the outer surface of the sack is covered with a polymer material.
Claim 96
Dependent Claim
71 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is formed into a sack and the outer surface of the sack is covered with a polymer material.
Claim 97
Dependent Claim
61 words
The replacement of claim 71 wherein said polymer material can include at least one of the group consisting of polypropylene, polylactic acid materials, polyesther polymer mesh, composites of collagen and BMP, titanium fiber with BMP with or without non-collagenase proteins, polydioxanone, polyphosphazenes and BMP, ceramic collagen composite, expanded polytetrafluoroethylene barrier membranes, and ethylene-vinyl acetate copolymers in methylene chloride (Elvax 40 ).
Claim 98
Dependent Claim
74 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 99
Dependent Claim
74 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is treated with at least one of the group consisting of: heparin, dextran, protease, elastase, collagenase, guanidine hydrochloride, and lithium bromide.
Claim 100
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is treated with one or more bone growth factors.
Claim 101
Dependent Claim
62 words
A replacement for at least part of a vertebral disk; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said hair is treated with one or more bone growth factors.
Claim 102
Dependent Claim
73 words
A replacement for at least part of a vertebral disk, the replacement comprised of hair formed in to a sack; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said sack is filled with one or more bone growth factor materials.
Claim 103
Dependent Claim
73 words
A replacement for at least part of a vertebral disk, the replacement comprised of hair formed in to a sack; wherein the replacement is comprised of at least a first layer of woven hair and a second layer of woven hair; wherein the hair in the first layer has a different orientation than the hair in the second layer; and wherein said sack is filled with one or more bone growth factor materials.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2007-06-08 | 2007-12-08 | 2008-06-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2011-06-08 | 2011-12-08 | 2012-06-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2015-06-08 | 2015-12-08 | 2016-06-08 | $7700.00 | Window Closed / Lapsed |