Patent US6676627B1 successfully refreshed from Google Patents.
US6676627B1
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Crossflow thrombectomy catheter and system
Assignee: Bayer Medical Care Inc
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Filing: 1999-10-13
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Granted: 2004-01-13
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Expires: 2019-10-13
Abstract
Abstract Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.
Inventors
- 👤 Michael J. Bonnette
- 👤 John Edward Morris
- 👤 Steven E. Wiesel
- 👤 John B. Bridgeman
- 👤 Debra M. Kozak
- 👤 Rosemary C. Beaupre
- 👤 Mark L. Jenson
- 👤 Cindy M. Setum
- 👤 Robert C. Dutcher
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:18
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/32; A61B17/3203; A61B17/32037; A61M; A61M1/00; A61M1/84; A61M1/85
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
429 words
An elongated device for treatment of thrombus or other unwanted material in a vessel or cavity of a living body comprising: a. a proximal end and a distal end; b. high pressure tubular means for conveying pressurized fluid from said proximal end to said distal end; c. pressurized fluid connection means for connecting the proximal end of said high pressure tubular means to a source of pressurized fluid; d. jet emanator means with at least one jet orifice for directing at least one high velocity fluid jet in the vicinity of said distal end, said jet emanator means being attached to and in fluid communication with said high pressure tubular means; e. exhaust tubular means for conveying fluid from said distal end to said proximal end, at least one of said jet orifices directing at least one high velocity fluid jet into said exhaust tubular means, said exhaust tubular means providing for removal of fluid and thrombus or other unwanted material debris from the body vessel or cavity; f. inflow means in said exhaust tubular means, oriented so that at least one high velocity fluid jet entrains and draws surrounding blood or other fluid from a body vessel or cavity through said inflow means and into said exhaust tubular means, and creating a region of elevated pressure in said exhaust tubular means; g. outflow means in said exhaust tubular means, located at said region of elevated pressure, said outflow means thereby providing for passage of fluid out from said exhaust tubular means into a body vessel or cavity, creating one or more cross stream jets which provide force (normal and/or drag forces) which help to break thrombus or other unwanted material off the surface of a body vessel or cavity; h. one or more of said high velocity jet(s) act to break apart thrombus or other unwanted material which has been entrained by said high velocity jet(s); i. said high velocity jet(s), said inflow means, and said outflow means create a recirculation pattern so that fluid flows from said outflow means with radial flow vectors and circumferential and/or axial flow vectors to said inflow means and back into said exhaust tubular means, thereby providing enhanced removal of thrombus or other unwanted material off the surface of a body vessel or cavity, and macerating the thrombus or other unwanted material by action of said high velocity jet(s); and, j. said elevated pressure in said exhaust tubular means aids in driving fluid and thrombus or unwanted material debris from said distal end to said proximal end through said exhaust tubular means.
Claim 2
Dependent Claim
429 words
An elongated device for treatment of thrombus or other unwanted material in a vessel or cavity of a living body comprising: a. a proximal end and a distal end; b. high pressure tubular means for conveying pressurized fluid from said proximal end to said distal end; c. pressurized fluid connection means for connecting the proximal end of said high pressure tubular means to a source of pressurized fluid; d. jet emanator means with at least one jet orifice for directing at least one high velocity fluid jet in the vicinity of said distal end, said jet emanator means being attached to and in fluid communication with said high pressure tubular means; e. exhaust tubular means for conveying fluid from said distal end to said proximal end, at least one of said jet orifices directing at least one high velocity fluid jet into said exhaust tubular means, said exhaust tubular means providing for removal of fluid and thrombus or other unwanted material debris from the body vessel or cavity; f. inflow means in said exhaust tubular means, oriented so that at least one high velocity fluid jet entrains and draws surrounding blood or other fluid from a body vessel or cavity through said inflow means and into said exhaust tubular means, and creating a region of elevated pressure in said exhaust tubular means; g. outflow means in said exhaust tubular means, located at said region of elevated pressure, said outflow means thereby providing for passage of fluid out from said exhaust tubular means into a body vessel or cavity, creating one or more cross stream jets which provide force (normal and/or drag forces) which help to break thrombus or other unwanted material off the surface of a body vessel or cavity; h. one or more of said high velocity jet(s) act to break apart thrombus or other unwanted material which has been entrained by said high velocity jet(s); i. said high velocity jet(s), said inflow means, and said outflow means create a recirculation pattern so that fluid flows from said outflow means with radial flow vectors and circumferential and/or axial flow vectors to said inflow means and back into said exhaust tubular means, thereby providing enhanced removal of thrombus or other unwanted material off the surface of a body vessel or cavity, and macerating the thrombus or other unwanted material by action of said high velocity jet(s); and, j. said elevated pressure in said exhaust tubular means aids in driving fluid and thrombus or unwanted material debris from said distal end to said proximal end through said exhaust tubular means.
Claim 3
Dependent Claim
21 words
The device of claim 1 , wherein high pressure fluid is provided in the range of approximately 150 to 500 psi.
Claim 4
Dependent Claim
21 words
The device of claim 1 , wherein high pressure fluid is provided in the range of approximately 500 to 2500 psi.
Claim 5
Dependent Claim
21 words
The device of claim 1 , wherein high pressure fluid is provided in the range of approximately 2500 to 50000 psi.
Claim 6
Dependent Claim
24 words
The device of claim 1 , wherein high pressure fluid in said jet emanator means is in the range of 50 to 350 psi.
Claim 7
Dependent Claim
24 words
The device of claim 1 , wherein high pressure fluid in said jet emanator means is in the range of 350 to 850 psi.
Claim 8
Dependent Claim
24 words
The device of claim 1 , wherein high pressure fluid in said jet emanator means is in the range of 850 to 35000 psi.
Claim 9
Dependent Claim
22 words
The device of claim 1 , wherein said high velocity jet(s) have maximum instantaneous centerline velocity of approximately 2,000 to 30,000 cm/s.
Claim 10
Dependent Claim
22 words
The device of claim 1 , wherein said high velocity jet(s) have maximum instantaneous centerline velocity of approximately 7,000 to 20,000 cm/s.
Claim 11
Dependent Claim
38 words
The device of claim 1 , further comprising another tubular means for passage of fluid or other material or for passage of devices such as guidewires, catheters, or imaging tools between said proximal end and said distal end.
Claim 12
Dependent Claim
29 words
The device of claim 1 , further comprising pressurized fluid source means connectible to said pressurized fluid connection means, for providing pressurized fluid to said high pressure tubular means.
Claim 13
Dependent Claim
39 words
The device of claim 1 , further comprising exhaust regulation means connected to said exhaust tubular means for regulation of the rate of removal of fluid and thrombus or other unwanted material debris from the body vessel or cavity.
Claim 14
Dependent Claim
131 words
A catheter comprising: a. a first tube having a proximal end and a distal end; b. a second tube having a proximal end and a distal end, said first tube residing within and extending along the length of said second tube; c. a jet body at said distal end of said first tube, said jet body including a jet emanator; d. at least one outflow orifice and at least one inflow orifice formed in said second tube adjacent to said distal end thereof; e. said jet emanator having at least one jet orifice directed toward said outflow and inflow orifices; and, f. said jet emanator located with respect to said outflow orifice such that at least some fluid directed by said jet emanator passes through said at least one outflow orifice.
Claim 15
Dependent Claim
131 words
A catheter comprising: a. a first tube having a proximal end and a distal end; b. a second tube having a proximal end and a distal end, said first tube residing within and extending along the length of said second tube; c. a jet body at said distal end of said first tube, said jet body including a jet emanator; d. at least one outflow orifice and at least one inflow orifice formed in said second tube adjacent to said distal end thereof; e. said jet emanator having at least one jet orifice directed toward said outflow and inflow orifices; and, f. said jet emanator located with respect to said outflow orifice such that at least some fluid directed by said jet emanator passes through said at least one outflow orifice.
Claim 16
Dependent Claim
25 words
The catheter as defined in claim 13 , wherein said at least one outflow orifice is located proximally of said at least one inflow orifice.
Claim 17
Dependent Claim
32 words
The catheter as defined in claim 13 , wherein said at least one outflow orifice comprises a plurality of orifices and said at least one inflow orifice comprises a plurality of orifices.
Claim 18
Dependent Claim
30 words
The catheter as defined in claim 15 , wherein all of said outflow orifices and all of said inflow orifices are positioned proximally of said at least one jet orifice.
Claim 19
Dependent Claim
23 words
The catheter as defined in claim 15 , wherein all of said outflow orifices are located proximally of all of said inflow orifices.
Claim 20
Dependent Claim
24 words
The catheter as defined in claim 13 , wherein said at least one jet orifice is located distally of said outflow and inflow orifices.
Claim 21
Dependent Claim
24 words
The catheter as defined in claim 13 , wherein said at least one jet orifice is located proximally of said outflow and inflow orifices.
Claim 22
Dependent Claim
21 words
The catheter as defined in claim 13 , wherein said at least one jet orifice comprises a plurality of jet orifices.
Claim 23
Dependent Claim
20 words
The catheter as defined in claim 13 , wherein said jet emanator is in the form of a toroidal loop.
Claim 24
Dependent Claim
20 words
The catheter as defined in claim 13 , wherein said jet emanator is in the form of a semi-toroidal loop.
Claim 25
Dependent Claim
14 words
The catheter as defined in claim 13 , wherein said jet emanator is L-shaped.
Claim 26
Dependent Claim
14 words
The catheter as defined in claim 13 , wherein said jet emanator is J-shaped.
Claim 27
Dependent Claim
26 words
The catheter as defined in claim 24 , wherein said at least one jet orifice is located in the curved portion of said J-shaped jet emanator.
Claim 28
Dependent Claim
26 words
The catheter as defined in claim 24 , wherein said at least one jet orifice is located at the extreme end of said J-shaped jet emanator.
Claim 29
Dependent Claim
37 words
The catheter as defined in claim 24 , wherein the extreme end of said J-shaped jet emanator includes a necked-down portion and said at least one jet orifice is located at the tip of said necked-down portion.
Claim 30
Dependent Claim
32 words
The catheter as defined in claim 24 , wherein said at least one jet orifice is defined by a tubular orifice member located at the extreme end of said J-shaped jet emanator.
Claim 31
Dependent Claim
31 words
The catheter as defined in claim 13 , wherein said at least one outflow orifice and said at least one inflow orifice are defined by separate regions of a single orifice.
Claim 32
Dependent Claim
23 words
The catheter as defined in claim 13 , further comprising a flexible tip assembly attached to said distal end of said second tube.
Claim 33
Dependent Claim
21 words
The catheter as defined in claim 30 , wherein said flexible tip assembly comprises a tapered tube housing a radio-opaque marker.
Claim 34
Dependent Claim
17 words
The catheter as defined in claim 31 , wherein said radio-opaque marker is a metal wire coil.
Claim 35
Dependent Claim
23 words
The catheter as defined in claim 32 , wherein said metal wire coil has a closely wound portion and a loosely wound portion.
Claim 36
Dependent Claim
26 words
The catheter as defined in claim 13 , wherein said jet emanator is located within said second tube at said distal end of said second tube.
Claim 37
Dependent Claim
27 words
The catheter as defined in claim 13 , wherein said jet emanator is located outside of said second tube beyond said distal end of said second tube.
Claim 38
Dependent Claim
16 words
The catheter as defined in claim 13 , wherein said second tube includes an exhaust lumen.
Claim 39
Dependent Claim
23 words
The catheter as defined in claim 13 , wherein said proximal ends of said first and second tubes are connected to a manifold.
Claim 40
Dependent Claim
18 words
The catheter of claim 13 further wherein said at least one outflow orifice comprises a plurality of orifices.
Claim 41
Dependent Claim
147 words
A catheter comprising: a. a first tube having a proximal end and a distal end; b. a second tube having a proximal end and a distal end, said first tube residing within and extending along the length of said second tube; c. a jet body at said distal end of said first tube, said jet body including a jet emanator; d. at least one outflow orifice and at least one inflow orifice formed in said second tube adjacent to said distal end thereof; e. said jet emanator having at least one jet orifice directed toward said outflow and inflow orifices; f. all of said outflow orifices are positioned proximally of said at least one jet orifice; and, g. said jet emanator located with respect to said outflow orifices such that at least some fluid directed by said jet emanator passes through said at least one outflow orifice.
Claim 42
Dependent Claim
147 words
A catheter comprising: a. a first tube having a proximal end and a distal end; b. a second tube having a proximal end and a distal end, said first tube residing within and extending along the length of said second tube; c. a jet body at said distal end of said first tube, said jet body including a jet emanator; d. at least one outflow orifice and at least one inflow orifice formed in said second tube adjacent to said distal end thereof; e. said jet emanator having at least one jet orifice directed toward said outflow and inflow orifices; f. all of said outflow orifices are positioned proximally of said at least one jet orifice; and, g. said jet emanator located with respect to said outflow orifices such that at least some fluid directed by said jet emanator passes through said at least one outflow orifice.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2007-01-12 | 2007-07-14 | 2008-01-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2011-01-12 | 2011-07-14 | 2012-01-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2015-01-12 | 2015-07-14 | 2016-01-13 | $7700.00 | Window Closed / Lapsed |