US6499487B1
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Implantable cerebral protection device and methods of use
Assignee: Edwards Lifesciences Corp
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Filing: 2000-08-17
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Granted: 2002-12-31
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Expires: 2020-08-17
Abstract
Abstract Described are devices and methods for diverting emboli away from the carotid arteries in the aorta. The devices are aortic diverters that generally comprise a hollow tube with a substantially cylindrical or conical wall, which is impermeable to emboli and which has open ends that allow blood to enter one end, flow through the tube and exit the other end. Additionally, snowshoe aortic diverters, which are planar rather than cylindrical are also shown. The methods of the invention generally include the steps of providing an aortic diverter carried by an intravascular catheter, introducing the intravascular catheter into the vascular system, advancing the intravascular catheter into the aortic arch to the region of the carotid arteries, and deploying the aortic diverter.
Inventors
- 👤 John McKenzie
- 👤 Sachiko Hattori
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:39
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12131; A61B17/12136; A61F2/01; A61F2/011; A61B17/00234; A61B2017/00238; A61B2017/00243; A61F2/24; A61F2/82; A61F2/86; A61F2/90; A61F2002/016; A61F2002/018; A61F2230/00; A61F2230/0002; A61F2230/0004; A61F2230/0006; A61F2230/0008; A61F2230/0017; A61F2230/0019; A61F2230/0063; A61F2230/0065; A61F2230/0069; A61F2230/0073; A61F2230/008; Y; Y10; Y10S; Y10S623/00; Y10S623/902
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
149 words
A method for protecting a patient against cerebral embolization, said method comprising the steps of: providing an aortic diverter comprising an elongate tube having a wall impermeable to emboli, the tube having a proximal end terminating in a substantially circular edge adapted to fill the lumen of the aorta, and a distal end, wherein the proximal and distal ends are substantially open allowing blood to enter the proximal end, flow through the tube, and exit the distal end; inserting the aortic diverter in the aortic arch; and positioning the aortic diverter so that the proximal end of the aortic diverter is upstream of the brachiocephalic trunk and the distal end of the aortic diverter is downstream of the left subclavian artery or the left brachiocephalic trunk, wherein emboli passing through the aortic arch flow through the aortic diverter and are diverted from the carotid arteries to the peripheral vasculature.
Claim 2
Independent Claim
149 words
A method for protecting a patient against cerebral embolization, said method comprising the steps of: providing an aortic diverter comprising an elongate tube having a wall impermeable to emboli, the tube having a proximal end terminating in a substantially circular edge adapted to fill the lumen of the aorta, and a distal end, wherein the proximal and distal ends are substantially open allowing blood to enter the proximal end, flow through the tube, and exit the distal end; inserting the aortic diverter in the aortic arch; and positioning the aortic diverter so that the proximal end of the aortic diverter is upstream of the brachiocephalic trunk and the distal end of the aortic diverter is downstream of the left subclavian artery or the left brachiocephalic trunk, wherein emboli passing through the aortic arch flow through the aortic diverter and are diverted from the carotid arteries to the peripheral vasculature.
Claim 3
Dependent Claim
14 words
The method of claim 1 , wherein the aortic diverter has a frustoconical shape.
Claim 4
Dependent Claim
17 words
The method of claim 1 , wherein the wall of the aortic diverter is permeable to blood.
Claim 5
Dependent Claim
19 words
The method of claim 1 , wherein the aortic diverter is inserted through an incision in the aortic arch.
Claim 6
Dependent Claim
19 words
The method of claim 1 , wherein the aortic diverter is inserted percutaneously and advanced through the descending aorta.
Claim 7
Dependent Claim
20 words
The method of claim 1 further comprising the step of securing the aortic diverter to the lumen of the aorta.
Claim 8
Independent Claim
104 words
A method for protecting a patient against cerebral embolization, comprising the steps of: providing a generally cylindrical membrane impermeable to emboli and having a first substantially circular edge and a second substantially circular edge; inserting the membrane into the aorta; and positioning the membrane in the aortic arch so that the first edge of the membrane is upstream of the brachiocephalic trunk and the second edge of the membrane is downstream of the left subclavian artery or the left brachiocephalic trunk, wherein emboli passing through the aortic arch flow through the cylindrical membrane and are diverted from the carotid arteries to the peripheral vasculature.
Claim 9
Independent Claim
104 words
A method for protecting a patient against cerebral embolization, comprising the steps of: providing a generally cylindrical membrane impermeable to emboli and having a first substantially circular edge and a second substantially circular edge; inserting the membrane into the aorta; and positioning the membrane in the aortic arch so that the first edge of the membrane is upstream of the brachiocephalic trunk and the second edge of the membrane is downstream of the left subclavian artery or the left brachiocephalic trunk, wherein emboli passing through the aortic arch flow through the cylindrical membrane and are diverted from the carotid arteries to the peripheral vasculature.
Claim 10
Dependent Claim
13 words
The method of claim 7 , wherein the membrane has a frustoconical shape.
Claim 11
Dependent Claim
13 words
The method of claim 7 , wherein the membrane is permeable to blood.
Claim 12
Dependent Claim
18 words
The method of claim 7 , wherein the membrane is inserted through an incision in the aortic arch.
Claim 13
Dependent Claim
18 words
The method of claim 7 , wherein the membrane is inserted percutaneously and advanced through the descending aorta.
Claim 14
Dependent Claim
20 words
The method of claim 7 , further comprising the step of securing the membrane to the lumen of the aorta.
Claim 15
Dependent Claim
54 words
An aortic diverter insertable in an aorta for diverting emboli away from the carotid arteries comprising a hollow tube impermeable to emboli, said tube being curved at an angle for placement in the aortic arch and having a substantially circular proximal edge with an opening and a substantially circular distal edge with an opening.
Claim 16
Dependent Claim
54 words
An aortic diverter insertable in an aorta for diverting emboli away from the carotid arteries comprising a hollow tube impermeable to emboli, said tube being curved at an angle for placement in the aortic arch and having a substantially circular proximal edge with an opening and a substantially circular distal edge with an opening.
Claim 17
Dependent Claim
14 words
The aortic diverter of claim 13 , wherein the tube is a flexible windsock.
Claim 18
Dependent Claim
14 words
The aortic diverter of claim 13 , wherein the tube is impermeable to blood.
Claim 19
Dependent Claim
14 words
The aortic diverter of claim 13 , wherein the tube comprises a woven material.
Claim 20
Dependent Claim
29 words
The aortic diverter of claim 13 , further comprising a flexible sleeve secured to the proximal edge, the sleeve being adapted to frictionally engage the lumen of the aorta.
Claim 21
Dependent Claim
36 words
The aortic diverter of claim 13 , wherein the tube is expandable between a compressed condition for percutaneous delivery to the aortic arch and an expanded condition for frictional engagement with the lumen of the aorta.
Claim 22
Dependent Claim
14 words
The aortic diverter of claim 13 , wherein the tube comprises a mesh material.
Claim 23
Independent Claim
110 words
A method for protecting a patient against cerebral embolization, said method comprising the steps of: providing an aortic diverter comprising an elongate tube having a wall impermeable to emboli, the tube having a proximal end terminating in a substantially circular edge adapted to fill the lumen of the aorta, and a distal end, wherein the proximal and distal ends are substantially open allowing blood to enter the proximal end, flow through the tube, and exist the distal end; positioning the aortic diverter within the aortic arch; and securing the aortic diverter to the lumen of the aorta, the proximal end of the aortic diverter extending upstream of the brachiocephalic trunk.
Claim 24
Independent Claim
110 words
A method for protecting a patient against cerebral embolization, said method comprising the steps of: providing an aortic diverter comprising an elongate tube having a wall impermeable to emboli, the tube having a proximal end terminating in a substantially circular edge adapted to fill the lumen of the aorta, and a distal end, wherein the proximal and distal ends are substantially open allowing blood to enter the proximal end, flow through the tube, and exist the distal end; positioning the aortic diverter within the aortic arch; and securing the aortic diverter to the lumen of the aorta, the proximal end of the aortic diverter extending upstream of the brachiocephalic trunk.
Claim 25
Dependent Claim
26 words
The method of claim 20 , wherein the aortic diverter is secured to the lumen of the aorta by frictionally engaging the lumen of the aorta.
Claim 26
Dependent Claim
34 words
The method of claim 20 , wherein the aortic diverter is frictionally engaged to the lumen of the aorta by radially expanding the aortic diverter into frictional engagement to the lumen of the aorta.
Claim 27
Dependent Claim
58 words
The method of claim 20 , wherein the aortic divert comprises a sleeve secured to the proximal end of the elongate tube, the sleeve being adapted to frictionally engage the lumen of the aorta, and wherein the aortic diverter is secured to the lumen of the aorta by frictionally engaging the sleeve to the lumen of the aorta.
Claim 28
Dependent Claim
26 words
The method of claim 23 , wherein the sleeve is frictionally engaged by radially expanding the sleeve into frictional engagement to the lumen of the aorta.
Claim 29
Dependent Claim
29 words
The method of claim 20 , wherein the aortic diverter is secured to the lumen of the aorta by suturing the aortic diverter to the lumen of the aorta.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2005-12-30 | 2006-07-01 | 2006-12-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-12-30 | 2010-07-01 | 2010-12-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-12-30 | 2014-07-01 | 2014-12-31 | $7700.00 | Window Closed / Lapsed |