US6139517A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Perfusion shunt apparatus and method
Assignee: Cardeon Corp
•
Filing: 1998-12-14
•
Granted: 2000-10-31
•
Expires: 2018-12-14
Abstract
Abstract A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directing circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directing blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta. The perfusion shunt apparatus has application for protecting a patient from embolic stroke or hypoperfusion during cardiopulmonary bypass or cardiac surgery and also for selectively perfusing the cerebrovascular circulation with oxygenated blood or with neuroprotective fluids in the presence of risk factors, such as head trauma or cardiac insufficiency. The perfusion shunt apparatus will also find application for selective perfusion of other organ systems within the body.
Inventors
- 👤 John A. Macoviak
- 👤 Wilfred J. Samson
- 👤 James J. Leary
- 👤 Brady D. Esch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:32
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1002; A61M1/00; A61M1/36; A61M1/3613; A61M1/3621; A61M1/3653; A61M1/3655; A61M1/3659; A61M2025/1043; A61M2025/1052; A61M2025/1097; A61M2210/00; A61M2210/12; A61M2210/127; A61M25/1011
Claims Analysis
Total Claims: 59
Claim 1
Independent Claim
146 words
A perfusion shunt apparatus for use in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having an upstream end and a downstream end and an internal lumen, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; a perfusion lumen within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit; and an occlusion member for selectively occluding said internal lumen of said expandable shunt conduit.
Claim 2
Dependent Claim
146 words
A perfusion shunt apparatus for use in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having an upstream end and a downstream end and an internal lumen, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; a perfusion lumen within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit; and an occlusion member for selectively occluding said internal lumen of said expandable shunt conduit.
Claim 3
Dependent Claim
17 words
The perfusion shunt apparatus of claim 1, wherein said upstream sealing member comprises an inflatable toroidal balloon.
Claim 4
Dependent Claim
29 words
The perfusion shunt apparatus of claim 1, wherein said upstream sealing member comprises an elongated expansion member extendible to expand said upstream end of said expandable shunt conduit proximate.
Claim 5
Dependent Claim
18 words
The perfusion shunt apparatus of claim 1, wherein said upstream sealing member comprises an external flow control valve.
Claim 6
Dependent Claim
29 words
The perfusion shunt apparatus of claim 1, wherein said expandable shunt conduit further comprises at least one longitudinal support member attached to a wall of said expandable shunt conduit.
Claim 7
Dependent Claim
23 words
The perfusion shunt apparatus of claim 1, wherein said expandable shunt conduit further comprises a wall of porous fabric enclosing said internal lumen.
Claim 8
Dependent Claim
29 words
The perfusion shunt apparatus of claim 6, wherein said expandable shunt conduit further comprises an end wall of porous fabric across said downstream end of said expandable shunt conduit.
Claim 9
Dependent Claim
23 words
The perfusion shunt apparatus of claim 1, further comprising an occlusion member for selectively occluding said internal lumen of said expandable shunt conduit.
Claim 10
Dependent Claim
25 words
The perfusion shunt apparatus of claim 1, further comprising an infusion lumen within said catheter shaft having an infusion port upstream of said occlusion member.
Claim 11
Dependent Claim
43 words
The perfusion shunt apparatus of claim 1, further comprising a downstream sealing member at said downstream end of said expandable shunt conduit for creating a seal between said downstream end of said expandable shunt conduit and the internal wall of the body passage.
Claim 12
Dependent Claim
17 words
The perfusion shunt apparatus of claim 10, wherein said upstream sealing member comprises an inflatable toroidal balloon.
Claim 13
Dependent Claim
17 words
The perfusion shunt apparatus of claim 11, wherein said downstream sealing member comprises an inflatable toroidal balloon.
Claim 14
Dependent Claim
28 words
The perfusion shunt apparatus of claim 10, wherein said upstream sealing member comprises an elongated expansion member extendible to expand said upstream end of said expandable shunt conduit.
Claim 15
Dependent Claim
28 words
The perfusion shunt apparatus of claim 13, wherein said downstream sealing member comprises an elongated expansion member extendible to expand said downstream end of said expandable shunt conduit.
Claim 16
Dependent Claim
18 words
The perfusion shunt apparatus of claim 10, wherein said upstream sealing member comprises an external flow control valve.
Claim 17
Dependent Claim
18 words
The perfusion shunt apparatus of claim 15, wherein said downstream sealing member comprises an external flow control valve.
Claim 18
Dependent Claim
20 words
The perfusion shunt apparatus of claim 10, wherein said downstream sealing member comprises a retrograde flow external flow control valve.
Claim 19
Dependent Claim
20 words
The perfusion shunt apparatus of claim 17, wherein said upstream sealing member comprises an antegrade flow external flow control valve.
Claim 20
Dependent Claim
18 words
The perfusion shunt apparatus of claim 10, further comprising at least one radiopaque marker located on said apparatus.
Claim 21
Dependent Claim
18 words
The perfusion shunt apparatus of claim 10, further comprising at least one sonoreflective marker located on said apparatus.
Claim 22
Dependent Claim
17 words
The perfusion shunt apparatus of claim 10, further comprising a light emitting device located on said apparatus.
Claim 23
Dependent Claim
29 words
The perfusion shunt apparatus of claim 10, wherein said expandable shunt conduit further comprises at least one longitudinal support member attached to a wall of said expandable shunt conduit.
Claim 24
Dependent Claim
23 words
The perfusion shunt apparatus of claim 10, wherein said expandable shunt conduit further comprises a wall of impermeable fabric enclosing said internal lumen.
Claim 25
Dependent Claim
23 words
The perfusion shunt apparatus of claim 10, wherein said expandable shunt conduit further comprises a wall of porous fabric enclosing said internal lumen.
Claim 26
Dependent Claim
17 words
The perfusion shunt apparatus of claim 10, further comprising a second perfusion lumen within said catheter shaft.
Claim 27
Dependent Claim
25 words
The perfusion shunt apparatus of claim 10, further comprising a tubular sheath sized to fit over said expandable shunt conduit when in said collapsed position.
Claim 28
Dependent Claim
23 words
The perfusion shunt apparatus of claim 10, further comprising an occlusion member for selectively occluding said internal lumen of said expandable shunt conduit.
Claim 29
Dependent Claim
25 words
The perfusion shunt apparatus of claim 10, further comprising an infusion lumen within said catheter shaft having an infusion port upstream of said occlusion member.
Claim 30
Dependent Claim
27 words
The perfusion shunt apparatus of claim 10, wherein said occlusion number comprises an inflatable occlusion balloon for selectively occluding said internal lumen of said expandable shunt conduit.
Claim 31
Dependent Claim
19 words
The perfusion shunt apparatus of claim 10, wherein said catheter shaft is positioned external to said expandable shunt conduit.
Claim 32
Dependent Claim
19 words
The perfusion shunt apparatus of claim 10, wherein said catheter shaft is positioned internal to said expandable shunt conduit.
Claim 33
Dependent Claim
27 words
The perfusion shunt apparatus of claim 10, further comprising a filter mesh configured to filter fluid flow passing through said internal lumen of said expandable shunt conduit.
Claim 34
Independent Claim
111 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion shunt catheter into the main vessel; expanding a shunt conduit mounted on said perfusion shunt catheter to open an internal lumen within said shunt conduit to fluid flow; sealing an upstream end of said expandable shunt conduit to an internal wall of the main vessel upstream of the branch vessel; perfusing the branch from a perfusion lumen in fluid communication with a space exterior to said shunt conduit. perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said shunt conduit.
Claim 35
Independent Claim
111 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion shunt catheter into the main vessel; expanding a shunt conduit mounted on said perfusion shunt catheter to open an internal lumen within said shunt conduit to fluid flow; sealing an upstream end of said expandable shunt conduit to an internal wall of the main vessel upstream of the branch vessel; perfusing the branch from a perfusion lumen in fluid communication with a space exterior to said shunt conduit. perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said shunt conduit.
Claim 36
Dependent Claim
29 words
The method of claim 33, further comprising sealing a downstream end of said expandable shunt conduit to an internal wall of the main vessel downstream of the branch vessel.
Claim 37
Dependent Claim
36 words
The method of claim 34, wherein said upstream end of said shunt conduit is sealed to the internal wall of the main vessel by inflating a toroidal balloon at said upstream end of said shunt conduit.
Claim 38
Dependent Claim
36 words
The method of claim 35, wherein said downstream end of said shunt conduit is sealed to the internal wall of the main vessel by inflating a toroidal balloon at said downstream end of said shunt conduit.
Claim 39
Dependent Claim
38 words
The method of claim 34, wherein said upstream end of said shunt conduit is sealed to the internal wall of the main vessel by extending an elongated expansion member to expand said upstream end of said shunt conduit.
Claim 40
Dependent Claim
38 words
The method of claim 37, wherein said downstream end of said shunt conduit is sealed to the internal wall of the main vessel by extending an elongated expansion member to expand said downstream end of said shunt conduit.
Claim 41
Dependent Claim
29 words
The method of claim 34, wherein said upstream end of said shunt conduit is sealed to the internal wall of the main vessel by an external flow control valve.
Claim 42
Dependent Claim
29 words
The method of claim 39, wherein said downstream end of said shunt conduit is sealed to the internal wall of the main vessel by an external flow control valve.
Claim 43
Dependent Claim
24 words
The method of claim 34, further comprising imaging said perfiusion shunt catheter with the aid a radiopaque marker located on said perfusion shunt catheter.
Claim 44
Dependent Claim
24 words
The method of claim 34, further comprising imaging said perfusion shunt catheter with the aid a sonoreflective marker located on said perfusion shunt catheter.
Claim 45
Dependent Claim
20 words
The method of claim 34, further comprising emitting light from a light emitting device located on said perfusion shunt catheter.
Claim 46
Dependent Claim
15 words
The method of claim 33, further comprising occluding said internal lumen of said shunt conduit.
Claim 47
Dependent Claim
23 words
The method of claim 33 further comprising infusing fluid into the main vessel upstream of said upstream end of said expandable shunt conduit.
Claim 48
Dependent Claim
19 words
The method of claim 33, further comprising filtering fluid flow passing through said internal lumen of said shunt conduit.
Claim 49
Dependent Claim
57 words
The method of claim 33, where in said perfusion shunt catheter is inserted into the patient's aorta; said upstream end of said expandable shunt conduit is sealed to an internal wall of the aorta upstream of the patient's brachiocephalic artery; and at least one of the patient's aortic arch branch vessels is perfused from said perfusion lumen.
Claim 50
Dependent Claim
29 words
The method of claim 47 further comprising infusing a cardioplegic agent into the patient's aorta upstream of said upstream end of said expandable shunt conduit to induce cardioplegic arrest.
Claim 51
Dependent Claim
80 words
The method of claim 34, wherein said perfusion shunt catheter is inserted into the patient's aorta; said upstream end of said expandable shunt conduit is sealed to an internal wall of the aorta upstream of the patient's brachiocephalic artery; said downstream end of said expandable shunt conduit is sealed to an internal wall of the aorta downstream of the patient's left subclavian artery; and at least one of the patient's aortic arch branch vessels is perfused from said perfusion lumen.
Claim 52
Dependent Claim
29 words
The method of claim 49 further comprising infusing a cardioplegic agent into the patient's aorta upstream of said upstream end of said expandable shunt conduit to induce cardioplegic arrest.
Claim 53
Dependent Claim
140 words
A perfusion shunt apparatus for us in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow and wherein said expandable shunt conduit further comprises at least one longitudinal support member attached to a wall of said expandable shunt conduit; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; and a perfusion lumen for within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit.
Claim 54
Dependent Claim
140 words
A perfusion shunt apparatus for us in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow and wherein said expandable shunt conduit further comprises at least one longitudinal support member attached to a wall of said expandable shunt conduit; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; and a perfusion lumen for within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit.
Claim 55
Dependent Claim
150 words
A perfusion shunt apparatus for use in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having an upstream end and a downstream end and in internal lumen, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow and wherein said expanded shunt conduit further comprises a wall of porous fabric enclosing said internal lumen; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; and a perfusion lumen for within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit.
Claim 56
Dependent Claim
150 words
A perfusion shunt apparatus for use in a body passage, comprising: a catheter shaft; an expandable shunt conduit mounted on said catheter shaft, said expandable shunt conduit having an upstream end and a downstream end and in internal lumen, said expandable shunt conduit having a collapsed position in which said expandable shunt conduit is collapsed toward said catheter shaft and an expanded position in which said internal lumen of said expandable shunt conduit is open to fluid flow and wherein said expanded shunt conduit further comprises a wall of porous fabric enclosing said internal lumen; an upstream sealing member at said upstream end of said expandable shunt conduit for creating a seal between said upstream end of said expandable shunt conduit and an internal wall of the body passage; and a perfusion lumen for within said catheter shaft in fluid communication with a space exterior to said expandable shunt conduit.
Claim 57
Dependent Claim
29 words
The perfusion shunt apparatus of claim 52, wherein said expandable shunt conduit further comprises an end wall of porous fabric across said downstream end of said expandable shunt conduit.
Claim 58
Independent Claim
106 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion shunt catheter into the main vessel; expanding a shunt conduit mounted on said perfusion shunt catheter to open an internal lumen within said shunt conduit to fluid flow; sealing an upstream end of said expandable shunt conduit to an internal wall of the main vessel upstream of the branch vessel; filtering fluid flow passing through said internal lumen of said shunt conduit; and perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said shunt conduit.
Claim 59
Independent Claim
106 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion shunt catheter into the main vessel; expanding a shunt conduit mounted on said perfusion shunt catheter to open an internal lumen within said shunt conduit to fluid flow; sealing an upstream end of said expandable shunt conduit to an internal wall of the main vessel upstream of the branch vessel; filtering fluid flow passing through said internal lumen of said shunt conduit; and perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said shunt conduit.
References Cited (Backward Citations)
US3995617A
Cited
US3991767A
Cited
US3996938A
Cited
US4192302A
Cited
US4423725A
Cited
US4494531A
Cited
US4592340A
Cited
US4705507A
Cited
US4926858A
Cited
DE3535641A1
Cited
US4795427A
Cited
US4723549A
Cited
US4793348A
Cited
US4817600A
Cited
US4873978A
Cited
US5152777A
Cited
US4969891A
Cited
US5059205A
Cited
US4950226A
Cited
US5195955A
Cited
US5222941A
Cited
US5176638A
Cited
US5306249A
Cited
US5090960A
Cited
US5163905A
Cited
US5460610A
Cited
US5108418A
Cited
US5496277A
Cited
US5129883A
Cited
US5135474A
Cited
US5108419A
Cited
US5167628A
Cited
US5415630A
Cited
US5716340A
Cited
US5558642A
Cited
US5375612A
Cited
US5324304A
Cited
US5342306A
Cited
DE4324637A1
Cited
US5380284A
Cited
US5613948A
Cited
US5505701A
Cited
US5549626A
Cited
US5904697A
Cited
US5695504A
Cited
US5817113A
Cited
US5674198A
Cited
WO1997017100A1
Cited
US5769816A
Cited
US5769870A
Cited
WO1997042879A1
Cited
US5797933A
Cited
WO1998002084A2
Cited
US5662671A
Cited
US5893841A
Cited
WO1998024377A1
Cited
US5846260A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-10-31 | 2004-05-01 | 2004-10-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-10-31 | 2008-05-01 | 2008-10-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-10-31 | 2012-05-01 | 2012-10-31 | $7700.00 | Window Closed / Lapsed |