US6238429B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biologic cabling
Assignee: Medtronic Inc
•
Filing: 1998-05-05
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Granted: 2001-05-29
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Expires: 2018-05-05
Abstract
Abstract A length of living conductive cells may be injected directly or may be grown to be attached to a fibrous matrix of material that provides for flexible structure so as to deliver a stimulation signal from one end of the biologic cable to the other to induce a physiologic reaction in body tissue.
Inventors
- 👤 H. Toby Markowitz
- 👤 Maura G. Donovan
- 👤 Khawar Mehdi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:47
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
98 words
A method of treatment of heart disease, comprising: identifying a first site within a patient's heart from which a desired electrical signal can be obtained; identifying a second site within the patient's heart, to which delivery of the electrical signal obtained at the first site is desired; coupling the first site to the second site by means of a biologic cable comprising an elongated structure of living cells capable of receiving the electrical signals from the first site, carrying the electrical signals along the length of the elongated structure and delivering said electrical signals to said second site.
Claim 2
Independent Claim
98 words
A method of treatment of heart disease, comprising: identifying a first site within a patient's heart from which a desired electrical signal can be obtained; identifying a second site within the patient's heart, to which delivery of the electrical signal obtained at the first site is desired; coupling the first site to the second site by means of a biologic cable comprising an elongated structure of living cells capable of receiving the electrical signals from the first site, carrying the electrical signals along the length of the elongated structure and delivering said electrical signals to said second site.
Claim 3
Dependent Claim
26 words
The method of claim 1 wherein the biologic cable of the coupling step comprises an elongated structure of living cells genetically altered to enhance their conductivity.
Claim 4
Dependent Claim
28 words
The method of claim 1 wherein the biologic cable of the coupling step comprises an elongated structure of living skeletal muscle myoblasts genetically altered to enhance their conductivity.
Claim 5
Dependent Claim
21 words
The method of claim 1 wherein the biologic cable of the coupling step comprises an elongated structure of living cardiac myoblasts.
Claim 6
Independent Claim
25 words
The method of claims 1 or 2 or 3 or 4 wherein the step of identifying the first site comprises identifying the patient's AV node.
Claim 7
Dependent Claim
19 words
The method of claim 5 wherein the step of identifying the second site comprises identifying the patient's His bundle.
Claim 8
Dependent Claim
19 words
The method of claim 5 wherein the step of identifying the second site comprises identifying the patient's Purkinje fibers.
Claim 9
Dependent Claim
29 words
A method according to claim 1 or claim 2 or claim 3 or claim 4 wherein the step of identifying the second site comprises identifying the patient's His bundle.
Claim 10
Dependent Claim
29 words
A method according to claim 1 or claim 2 or claim 3 or claim 4 wherein the step of identifying the second site comprises identifying the patient's Purkinje fibers.
Claim 11
Dependent Claim
30 words
A method according to claim 1 or claim 2 or claim 3 or claim 4 wherein the biologic cable of the coupling step comprises an electrode at an end thereof.
Claim 12
Independent Claim
74 words
A method of treatment of heart disease comprising: identifying a site within a patient's heart to which delivery of electrical signals is desired; coupling the site to an electrical pulse generator by means of a biologic cable comprising an elongated structure of living cells capable of receiving the electrical signals from the electrical pulse generator, carrying the electrical signals along the length of the elongated structure and delivering said electrical signals to the site.
Claim 13
Independent Claim
74 words
A method of treatment of heart disease comprising: identifying a site within a patient's heart to which delivery of electrical signals is desired; coupling the site to an electrical pulse generator by means of a biologic cable comprising an elongated structure of living cells capable of receiving the electrical signals from the electrical pulse generator, carrying the electrical signals along the length of the elongated structure and delivering said electrical signals to the site.
Claim 14
Dependent Claim
27 words
A method according to claim 11 wherein the biologic cable of the coupling step comprises an elongated structure of living cells genetically altered to enhance their conductivity.
Claim 15
Dependent Claim
28 words
The method of claim 11 wherein the biologic cable of the coupling step comprises an elongated structure of living skeletal muscle myoblasts genetically altered to enhance their conductivity.
Claim 16
Dependent Claim
21 words
The method of claim 11 wherein the biologic cable of the coupling step comprises an elongated structure of living cardiac myoblasts.
Claim 17
Dependent Claim
29 words
A method according to claim 11 or 12 or 13 or 14 wherein the step of identifying said site within said patient's heart comprises identifying said patients His bundle.
Claim 18
Dependent Claim
28 words
The method of claim 11 or 12 or 13 or 14 wherein said step of identifying said site within said patient's heart comprises identifying said patient's Purkinje fibers.
Claim 19
Dependent Claim
26 words
The method of claim 11 or 12 or 13 or 14 wherein the biologic cable of the coupling step comprises an electrode at an end thereof.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-05-28 | 2004-11-27 | 2005-05-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-05-28 | 2008-11-27 | 2009-05-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-05-28 | 2012-11-27 | 2013-05-29 | $7700.00 | Window Closed / Lapsed |