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US6146323A Expired / Lapsed US ⏱️ 0.0 years remaining

Delivery catheter for a radioisotope stent

Assignee: IsoStent Inc
•
Filing: 1999-05-14
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Granted: 2000-11-14
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Expires: 2019-05-14
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Abstract

Abstract Disclosed is a stent delivery catheter system for placing a radioactive stent within a blockage in a vessel of a human body. The stent delivery catheter system consists of a radioactive stent that is placed onto an angioplasty balloon that is located at the distal portion of a stent delivery catheter. Just proximal and just distal to the stent there is a proximal radioactive band and a distal radioactive band, respectively, each of which are generally thin walled and cylindrical. The radioactive stent located on the balloon at the distal portion of the stent delivery catheter is advanced over a flexible guide wire until the non-deployed radioactive stent is placed at the site of a vessel blockage such as an arterial stenosis. The balloon is inflated and the radioactive stent and the distal and proximal radioactive bands are pushed radially outward in apposition to the wall of the artery, resulting in dilatation of the stenosis. The balloon remains expanded for several minutes, which maintains the proximal radioactive band and the distal radioactive band against the artery wall at positions that are just proximal and just distal to the edges of the stent. By this means, the regions of the vessel wall that are just proximal and just distal to the edges of the stent experience a sufficient dose of radiation so that the cells in that region become incapable of producing growth factor.

Inventors

  • 👤 Robert E. Fischell

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 20:05
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/95; A61F2/958; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61F2210/00; A61F2210/0095; A61N2005/1004

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 181 words
A stent delivery catheter system for placing a radioactive stent within a stenosis of a vessel in a human body, the system comprising: a flexible guide wire; a stent delivery catheter; the stent delivery catheter having a distal portion; the stent delivery catheter having an angioplasty balloon adapted for inflation by injectable inflation fluid, the balloon being located at the distal portion of the stent delivery catheter and having a proximal and a distal end; the stent delivery catheter having a radioactive stent mounted co-axially around the angioplasty balloon; the radioactive stent having a proximal end and a distal end; the stent delivery catheter also having a proximal radioactive band and a distal radioactive band; the proximal and distal radioactive bands being generally thin walled and cylindrical; the proximal radioactive band having a distal end located in proximity to the proximal end of the radioactive stent; the distal radioactive band having a proximal end located in proximity to the distal end of the radioactive stent; the proximal and distal radioactive bands adapted to be moved in apposition to the vessel wall.
Claim 2
Dependent Claim 181 words
A stent delivery catheter system for placing a radioactive stent within a stenosis of a vessel in a human body, the system comprising: a flexible guide wire; a stent delivery catheter; the stent delivery catheter having a distal portion; the stent delivery catheter having an angioplasty balloon adapted for inflation by injectable inflation fluid, the balloon being located at the distal portion of the stent delivery catheter and having a proximal and a distal end; the stent delivery catheter having a radioactive stent mounted co-axially around the angioplasty balloon; the radioactive stent having a proximal end and a distal end; the stent delivery catheter also having a proximal radioactive band and a distal radioactive band; the proximal and distal radioactive bands being generally thin walled and cylindrical; the proximal radioactive band having a distal end located in proximity to the proximal end of the radioactive stent; the distal radioactive band having a proximal end located in proximity to the distal end of the radioactive stent; the proximal and distal radioactive bands adapted to be moved in apposition to the vessel wall.
Claim 3
Dependent Claim 18 words
The system of claim 1 wherein the proximal and distal radioactive bands include a beta particle emitting radioisotope.
Claim 4
Dependent Claim 13 words
The system of claim 2 wherein the beta particle emitting isotope is phosphorous-32.
Claim 5
Dependent Claim 13 words
The system of claim 2 wherein the beta particle emitting isotope is yttrium-90.
Claim 6
Dependent Claim 18 words
The system of claim 1 wherein the proximal and distal radioactive bands include a gamma ray emitting radioisotope.
Claim 7
Dependent Claim 17 words
The system of claim 1 wherein the proximal and distal radioactive bands include an x-ray emitting radioisotope.
Claim 8
Dependent Claim 25 words
The system of claim 1 wherein the proximal and distal radioactive bands each have a radioactive activity level that lies between 1 and 100 milliCuries.
Claim 9
Dependent Claim 63 words
The system of claim 1 wherein the balloon angioplasty catheter has an inner shaft for the passage of the flexible guide wire; and located in the distal portion of the balloon angioplasty catheter a radiopaque marker band is located co-axially over the inner shaft and co-axially under the radioactive stent and is centered between the proximal and distal ends of the radioactive stent.
Claim 10
Dependent Claim 14 words
The system of claim 1 wherein the proximal and distal radioactive bands are radiopaque.
Claim 11
Dependent Claim 47 words
The system of claim 1 wherein the proximal radioactive band is adhesively joined to the proximal section of the angioplasty balloon along a narrow longitudinal line and the distal radioactive band is adhesively joined to the distal section of the angioplasty balloon along a narrow longitudinal line.
Claim 12
Dependent Claim 37 words
The system of claim 1 wherein the stent delivery catheter includes a guide wire lumen and an oxygenation guide wire is placed through the guide wire lumen to perfuse the tissue located distally to the angioplasty balloon.

References Cited (Backward Citations)

US5059166A Cited
US5484384A Cited
US5302168A Cited
US5411466A Cited
US5730698A Cited
US5879282A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-11-14 2004-05-15 2004-11-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-11-14 2008-05-15 2008-11-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-11-14 2012-05-15 2012-11-14 $7700.00 Window Closed / Lapsed

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