US6083220A
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US
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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
Assignee: CALIFORNIA UNIVERSITY OF REGENTS OF THEQ
Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.
A wire for use in the formation of an occlusion within a vascular cavity in conjunction with a microcatheter having an interior lumen, said wire comprising: a metal coil having a first shape which conforms to said microcatheter lumen when within the microcatheter, and said metal coil forming an unbiased, regular cylindrical or unbiased single regular conical envelope when disposed out of said microcatheter.
Claim 2
Dependent Claim
64 words
A wire for use in the formation of an occlusion within a vascular cavity in conjunction with a microcatheter having an interior lumen, said wire comprising: a metal coil having a first shape which conforms to said microcatheter lumen when within the microcatheter, and said metal coil forming an unbiased, regular cylindrical or unbiased single regular conical envelope when disposed out of said microcatheter.
Claim 3
Dependent Claim
10 words
The wire of claim 1 wherein the wire comprises platinum.
Claim 4
Dependent Claim
15 words
The wire of claim 1 wherein the diameter of the coil is approximately 0.001-0.005 inch.
Claim 5
Dependent Claim
15 words
The wire of claim 1 wherein the diameter of the coil is approximately 0.010-0.020 inch.
Claim 6
Dependent Claim
15 words
The wire of claim 1 wherein the diameter of the envelope is approximately 2-10 mm.
Claim 7
Dependent Claim
10 words
The wire of claim 1 wherein the envelope is conical.
Claim 8
Dependent Claim
10 words
The wire of claim 1 wherein the envelope is cylindrical.
Claim 9
Dependent Claim
16 words
The wire of claim 1 further comprising a plurality of filaments extending from said first shape.
Claim 10
Dependent Claim
10 words
The wire of claim 8 wherein the filaments comprise polyester.
Claim 11
Dependent Claim
17 words
The wire of claim 2 wherein the coil is prebiased to form said cylindrical or conical envelope.